Brief Information of the Compound and Protein
Compound Name
N-[[3,5-bis(trifluoromethyl)phenyl]methyl]-N-[(4-phenylpyridin-3-yl)methyl]thiophene-2-carboxamide
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PubChem ID
CID: 73350994
Canonical SMILES
FC(F)(F)c1cc(CN(Cc2cnccc2-c2ccccc2)C(=O)c2cccs2)cc(c1)C(F)(F)F
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Compound Formula C26H18F6N2OS
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 260 nM
   TI
   LI
   LO
   TS