Brief Information of the Compound and Protein
Compound Name
[(4R)-3-[[5-chloro-2-(trifluoromethyl)phenyl]methyl]-1,3-thiazolidin-4-yl]-(4-cyclopropyl-2,3-dihydroquinoxalin-1-yl)methanone
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PubChem ID
CID: 145971348
Canonical SMILES
FC(F)(F)c1ccc(Cl)cc1CN1CSC[C@H]1C(=O)N1CCN(C2CC2)c2ccccc12
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Compound Formula C23H23ClF3N3OS
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Lipid-like ligand receptor (family A GPCR)
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Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 39.81 nM
   TI
   LI
   LO
   TS