Brief Information of the Compound and Protein
Compound Name
4-(2,5-dichlorophenoxy)-N-ethyl-N-(2-methylphenyl)pyrimidine-5-carboxamide
    Show/Hide
PubChem ID
CID: 71457417
SID: 163530216
Canonical SMILES
CCN(C(=O)c1cncnc1Oc1cc(Cl)ccc1Cl)c1ccccc1C
    Show/Hide
Compound Formula C20H17Cl2N3O2
Compound Structure
Protein Name
G-protein coupled bile acid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Steroid-like ligand receptor
Uniprot ID
Q8TDU6
Gene Name
GPBAR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
EC50 = 4886 nM
   TI
   LI
   LO
   TS