| Compound ID |
Compound Name |
Compound Formula |
|
CP0550222
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-chlorophenyl)pyridin-2-yl)acetamide
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|
C19H24ClN3O2
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0570130
|
(S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trifluoromethoxy)phenyl)pyridin-2-yl)carbamate
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|
C21H26F3N3O4
|
1
|
| 1 |
IC50 = 0.2 nM
|
|
|
|
CP0572846
|
(S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-4-(trifluoromethyl)-[2,4′-bipyridin]-2′-yl)carbamate
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|
C20H25F3N4O3
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0576653
|
(S)-N-(4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trifluoromethyl)phenyl)pyridin-2-yl)acetamide
Show/Hide
|
C21H26F3N3O2
|
1
|
| 1 |
IC50 = 0.4 nM
|
|
|
|
CP0576652
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-(trifluoromethoxy)phenyl)pyridin-2-yl)acetamide
Show/Hide
|
C20H24F3N3O3
|
1
|
| 1 |
IC50 = 0.45 nM
|
|
|
|
CP0545257
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-cyanophenyl)pyridin-2-yl)acetamide
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|
C20H24N4O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0569337
|
(S)-1-((2′,4-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
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|
C19H23F4N3O
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0579819
|
(S)-N-(4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(difluoromethyl)phenyl)pyridin-2-yl)acetamide
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|
C21H27F2N3O2
|
1
|
| 1 |
IC50 = 0.5 nM
|
|
|
|
CP0568346
|
(S)-N-(4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-cyanophenyl)pyridin-2-yl)acetamide
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|
C21H26N4O2
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0579170
|
(S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(difluoromethyl)phenyl)pyridin-2-yl)carbamate
Show/Hide
|
C21H27F2N3O3
|
1
|
| 1 |
IC50 = 0.6 nM
|
|
|
|
CP0570410
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-(trifluoromethyl)phenyl)pyridin-2-yl)acetamide
Show/Hide
|
C20H24F3N3O2
|
1
|
| 1 |
IC50 = 0.75 nM
|
|
|
|
CP0261910
|
(S)-1-(2-(difluoromethyl)-4-(2-methylpyridin-4-yl)phenoxy)-2,4-dimethylpentan-2-amine
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|
C20H26F2N2O
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0576583
|
methyl N-[4-[4-[(2S)-2-amino-2,4-dimethylpentoxy]-3-methylphenyl]pyridin-2-yl]carbamate
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|
C21H29N3O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0579169
|
(S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-cyanophenyl)pyridin-2-yl)carbamate
Show/Hide
|
C21H26N4O3
|
1
|
| 1 |
IC50 = 0.8 nM
|
|
|
|
CP0261912
|
(S)-1-(2-(difluoromethyl)-4-(2-(difluoromethyl)pyridin-4-yl)phenoxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C20H24F4N2O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0550190
|
(S)-1-((4-(difluoromethyl)-2′-methyl-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
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|
C19H25F2N3O
|
1
|
| 1 |
IC50 = 0.9 nM
|
|
|
|
CP0578064
|
(S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-cyclopropylphenyl)pyridin-2-yl)carbamate
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|
C23H31N3O3
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0574558
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-methylphenyl)pyridin-2-yl)acetamide
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|
C20H27N3O2
|
1
|
| 1 |
IC50 = 1.1 nM
|
|
|
|
CP0576582
|
(S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-fluorophenyl)pyridin-2-yl)carbamate
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|
C20H26FN3O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0579392
|
(S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-chloro-[2,4′-bipyridin]-2′-yl)carbamate
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|
C19H25ClN4O3
|
1
|
| 1 |
IC50 = 1.2 nM
|
|
|
|
CP0574559
|
methyl N-[4-[4-[(2S)-2-amino-2,4-dimethylpentoxy]-3-chlorophenyl]pyridin-2-yl]carbamate
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|
C20H26ClN3O3
|
1
|
| 1 |
IC50 = 1.4 nM
|
|
|
|
CP0579391
|
(S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trifluoromethyl)phenyl)pyridin-2-yl)carbamate
Show/Hide
|
C21H26F3N3O3
|
1
|
| 1 |
IC50 = 1.5 nM
|
|
|
|
CP0550224
|
(S)-N-(4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(trifluoromethoxy)phenyl)pyridin-2-yl)acetamide
Show/Hide
|
C21H26F3N3O3
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0579168
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluorophenyl)pyridin-2-yl)acetamide
Show/Hide
|
C19H24FN3O2
|
1
|
| 1 |
IC50 = 1.6 nM
|
|
|
|
CP0970190
|
(S)-1-((4-chloro-2'-methyl-[2,4'-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C18H24ClN3O
|
1
|
| 1 |
IC50 = 1.9 nM
|
|
|
|
CP0261975
|
(S)-1-((2′,6-bis(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C19H23F4N3O
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0576584
|
(S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-methyl-[2,4′-bipyridin]-2′-yl)carbamate
Show/Hide
|
C20H28N4O3
|
1
|
| 1 |
IC50 = 2.4 nM
|
|
|
|
CP0578065
|
(S)-1-((2′-chloro-4-(difluoromethyl)-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C18H22ClF2N3O
|
1
|
| 1 |
IC50 = 2.7 nM
|
|
|
|
CP0568314
|
methyl N-[4-[6-[(2S)-2-amino-2,4-dimethylpentoxy]-5-methylpyridin-3-yl]pyridin-2-yl]carbamate
Show/Hide
|
C20H28N4O3
|
1
|
| 1 |
IC50 = 3.4 nM
|
|
|
|
CP0545258
|
(S)-N-(4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-fluorophenyl)pyridin-2-yl)acetamide
Show/Hide
|
C20H26FN3O2
|
1
|
| 1 |
IC50 = 3.7 nM
|
|
|
|
CP0578755
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-methoxyphenyl)pyridin-2-yl)acetamide
Show/Hide
|
C20H27N3O3
|
1
|
| 1 |
IC50 = 3.8 nM
|
|
|
|
CP0569336
|
(S)-methyl (4-(4-((2-amino-2,4-dimethylpentyl)oxy)-3-(hydroxymethyl)phenyl)pyridin-2-yl)carbamate
Show/Hide
|
C21H29N3O4
|
1
|
| 1 |
IC50 = 3.9 nM
|
|
|
|
CP0576581
|
(S)-methyl (4-(4-((2-amino-4-methylpentyl)oxy)-3-(isoxazol-5-yl)phenyl)pyridin-2-yl)carbamate
Show/Hide
|
C22H26N4O4
|
1
|
| 1 |
IC50 = 4.1 nM
|
|
|
|
CP0579172
|
methyl N-[4-[6-[(2S)-2-amino-2,4-dimethylpentoxy]-5-chloropyridin-3-yl]pyridin-2-yl]carbamate
Show/Hide
|
C19H25ClN4O3
|
1
|
| 1 |
IC50 = 4.2 nM
|
|
|
|
CP0576580
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-fluoro-5-(trifluoromethyl)phenyl)pyridin-2-yl)acetamide
Show/Hide
|
C20H23F4N3O2
|
1
|
| 1 |
IC50 = 4.8 nM
|
|
|
|
CP0578664
|
(S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-(difluoromethyl)pyridin-4-yl)benzonitrile
Show/Hide
|
C20H23F2N3O
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0580159
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-2,5-difluorophenyl)pyridin-2-yl)acetamide
Show/Hide
|
C19H23F2N3O2
|
1
|
| 1 |
IC50 = 6.7 nM
|
|
|
|
CP0576579
|
(S)-N-(4-(4-((2-amino-4-methylpentyl)oxy)-3-chloro-5-fluorophenyl)pyridin-2-yl)acetamide
Show/Hide
|
C19H23ClFN3O2
|
1
|
| 1 |
IC50 = 6.8 nM
|
|
|
|
CP0489392
|
(2S)-1-[5-(2-chloropyridin-4-yl)-3-methylpyridin-2-yl]oxy-2,4-dimethylpentan-2-amine
Show/Hide
|
C18H24ClN3O
|
1
|
| 1 |
IC50 = 7.6 nM
|
|
|
|
CP0275628
|
(S)-1-(4-(2-(difluoromethyl)pyridin-4-yl)-2-(trifluoromethyl)phenoxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C20H23F5N2O
|
1
|
| 1 |
IC50 = 7.8 nM
|
|
|
|
CP0576578
|
N-[4-[4-[(2S)-2-amino-4-methylpentoxy]phenyl]pyridin-2-yl]acetamide
Show/Hide
|
C19H25N3O2
|
1
|
| 1 |
IC50 = 8.1 nM
|
|
|
|
CP0575064
|
(S)-1-(2-cyclopropyl-4-(2-(difluoromethyl)pyridin-4-yl)phenoxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C22H28F2N2O
|
1
|
| 1 |
IC50 = 8.5 nM
|
|
|
|
CP0575065
|
(S)-1-((2′-chloro-5-(difluoromethyl)-[3,4′-bipyridin]-6-yl)oxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C18H22ClF2N3O
|
1
|
| 1 |
IC50 = 9.1 nM
|
|
|
|
CP0578035
|
(2S)-1-[5-[2-(difluoromethyl)pyridin-4-yl]-3-methylpyridin-2-yl]oxy-2,4-dimethylpentan-2-amine
Show/Hide
|
C19H25F2N3O
|
1
|
| 1 |
IC50 = 9.2 nM
|
|
|
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CP0580012
|
methyl N-[4-[4-[(2S)-2-amino-2,4-dimethylpentoxy]-2,3-dimethylphenyl]pyridin-2-yl]carbamate
Show/Hide
|
C22H31N3O3
|
1
|
| 1 |
IC50 = 9.7 nM
|
|
|
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CP0574806
|
(S)-1-((6-(difluoromethyl)-2′-methyl-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C19H25F2N3O
|
1
|
| 1 |
IC50 = 11 nM
|
|
|
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CP0579173
|
(S)-1-((2′-(difluoromethyl)-4-methyl-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C19H25F2N3O
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
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CP0580026
|
(S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-4-methyl-[2,4′-bipyridin]-2′-yl)carbamate
Show/Hide
|
C20H28N4O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0489393
|
(S)-1-((6-chloro-2′-methyl-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C18H24ClN3O
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0578081
|
2-[(1S)-1-amino-3-methylbutyl]-6-pyridin-4-ylquinoline-4-carbonitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
IC50 = 19 nM
|
|
|
|
CP0543984
|
(S)-2-((2-amino-2,4-dimethylpentyl)oxy)-5-(2-methylpyridin-4-yl)benzonitrile
Show/Hide
|
C20H25N3O
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0261909
|
(S)-2,4-dimethyl-1-(4-(2-methylpyridin-4-yl)-2-(trifluoromethyl)phenoxy)pentan-2-amine
Show/Hide
|
C20H25F3N2O
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0261911
|
(S)-2,4-dimethyl-1-(4-(pyridin-4-yl)-2-(trifluoromethyl)phenoxy)pentan-2-amine
Show/Hide
|
C19H23F3N2O
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0579654
|
2-[(1S)-1-amino-3-methylbutyl]-6-(1,3-oxazol-5-yl)quinoline-4-carbonitrile
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|
C18H18N4O
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0580042
|
(1S)-1-[4-ethyl-7-methoxy-6-(1,3-oxazol-5-yl)quinazolin-2-yl]-3-methylbutan-1-amine
Show/Hide
|
C19H24N4O2
|
1
|
| 1 |
IC50 = 34 nM
|
|
|
|
CP0575063
|
(S)-1-(2-cyclopropyl-4-(2-methylpyridin-4-yl)phenoxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C22H30N2O
|
1
|
| 1 |
IC50 = 36 nM
|
|
|
|
CP0550932
|
(2S)-4-methyl-1-(4-pyridin-4-ylphenoxy)pentan-2-amine
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|
C17H22N2O
|
1
|
| 1 |
IC50 = 48 nM
|
|
|
|
CP0580223
|
(1S)-1-[4-ethyl-6-(1,3-oxazol-5-yl)quinazolin-2-yl]-3-methylbutan-1-amine
Show/Hide
|
C18H22N4O
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0268029
|
(2R)-2-amino-N-[3-(difluoromethoxy)-4-(1,3-oxazol-5-yl)phenyl]-4-methylpentanamide
Show/Hide
|
C16H19F2N3O3
|
1
|
| 1 |
IC50 = 51 nM
|
|
|
|
CP0572128
|
(2S)-1-[3-chloro-5-(2-methylpyridin-4-yl)pyridin-2-yl]oxy-2,4-dimethylpentan-2-amine
Show/Hide
|
C18H24ClN3O
|
1
|
| 1 |
IC50 = 80 nM
|
|
|
|
CP0549612
|
(S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-methylpyridin-4-yl)benzonitrile
Show/Hide
|
C19H23N3O
|
1
|
| 1 |
IC50 = 89 nM
|
|
|
|
CP0576663
|
2-[(1R)-1-amino-3-methylbutyl]-6-pyridin-4-ylquinoline-4-carbonitrile
Show/Hide
|
C20H20N4
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0573765
|
(S)-1-(4-(2-fluoropyridin-4-yl)-2-(trifluoromethyl)phenoxy)-2,4-dimethylpentan-2-amine
Show/Hide
|
C19H22F4N2O
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0543983
|
(S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-(trifluoromethyl)pyridin-4-yl)benzonitrile
Show/Hide
|
C19H20F3N3O
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
|
CP0572127
|
(S)-2-((2-amino-4-methylpentyl)oxy)-5-(2-methoxypyridin-4-yl)benzonitrile
Show/Hide
|
C19H23N3O2
|
1
|
| 1 |
IC50 > 100 nM
|
|
|
