Brief Information of the Compound and Protein
Compound Name
(1S)-1-[4-ethyl-6-(1,3-oxazol-5-yl)quinazolin-2-yl]-3-methylbutan-1-amine
    Show/Hide
Canonical SMILES
CCc1nc(nc2ccc(cc12)-c1cnco1)[C@@H](N)CC(C)C
    Show/Hide
Compound Formula C18H22N4O
Compound Structure
Protein Name
AP2-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase NAK family
Uniprot ID
Q2M2I8
Gene Name
AAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F Homo sapiens (Human)  1
1
IC50 = 49 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 30 nM