Brief Information of the Compound and Protein
Compound Name
(S)-1-((4-(difluoromethyl)-2′-methyl-[2,4′-bipyridin]-5-yl)oxy)-2,4-dimethylpentan-2-amine
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PubChem ID
CID: 118429629
Canonical SMILES
CC(C)C[C@](C)(N)COc1cnc(cc1C(F)F)-c1ccnc(C)c1
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Compound Formula C19H25F2N3O
Compound Structure
Protein Name
AP2-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase NAK family
Uniprot ID
Q2M2I8
Gene Name
AAK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000131 HEK293-F Homo sapiens (Human)  1
1
IC50 = 0.9 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.5 nM