Brief Information of the Cell Line and Protein
Cell Line ID: CL000017 , HeLa
Synonyms
HELA
Hela
He La
He-La
HeLa-CCL2
Henrietta Lacks cells
Helacyton gartleri
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0030
Protein ID: PT01443 , Polyamine deacetylase HDAC10
Gene Name HDAC10
Organism Homo sapiens, Human
Protein Classification Epigenetic regulator
Uniprot ID Q969S8
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000017  Protein ID: PT01443
 
Compound ID Compound Name Compound Formula
CP0004941
N-hydroxy-4-[[3-(pyrrolidin-1-ylmethyl)indol-1-yl]methyl]benzamide
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C21H23N3O2
 1
1
IC50 = 3.981 nM
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CP0014425
4-[[3-[(dimethylamino)methyl]indol-1-yl]methyl]-N-hydroxybenzamide
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C19H21N3O2
 1
1
IC50 = 3.981 nM
   TI
   LI
   LO
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CP0014760
N-hydroxy-4-[[3-(1-methylpyrrolidin-2-yl)indol-1-yl]methyl]benzamide
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C21H23N3O2
 1
1
IC50 = 5.012 nM
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CP0008445
3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide
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C21H23N3O5
 1
1
IC50 = 7.943 nM
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CP0007846
N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]benzamide
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C20H21N3O2
 1
1
IC50 = 12.59 nM
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CP0007527
4-[[3-[(dimethylamino)methyl]indazol-1-yl]methyl]-N-hydroxybenzamide
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C18H20N4O2
 1
1
IC50 = 15.85 nM
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CP0129460
US9249087, 19
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C20H23N3O2
 1
1
IC50 = 25.12 nM
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CP0008777
JNJ-26481585
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C21H26N6O2
 1
1
IC50 = 39.81 nM
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CP0014641
N-hydroxy-4-[[3-(3-methylimidazol-4-yl)indol-1-yl]methyl]benzamide
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C20H18N4O2
 1
1
IC50 = 50.12 nM
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CP0011675
N-hydroxy-4-[(2-methyl-3,4-dihydro-1H-pyrido[3,4-b]indol-9-yl)methyl]benzamide
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C20H21N3O2
 1
1
IC50 = 158.49 nM
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CP0119682
US9249087, 2
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C16H14N2O2
 1
1
IC50 = 158.49 nM
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CP0244186
N-hydroxy-4-[[3-(2-methoxyethyl)indol-1-yl]methyl]benzamide
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C19H20N2O3
 1
1
IC50 = 199.53 nM
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CP0562872
N-hydroxy-4-[[3-(2-hydroxyethyl)indol-1-yl]methyl]benzamide
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C18H18N2O3
 1
1
IC50 = 199.53 nM
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CP0473253
tert-butyl N-[[1-[[4-(hydroxycarbamoyl)phenyl]methyl]indol-3-yl]methyl]carbamate
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C22H25N3O4
 1
1
IC50 = 251.19 nM
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CP0013041
HPOB
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C17H18N2O4
 1
1
IC50 = 316.23 nM
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CP0064131
7-(4-(3-Ethynylphenylamino)-7-methoxyquinazolin-6-yloxy)-N-hydroxyheptanamide
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C24H26N4O4
 1
1
IC50 = 398.11 nM
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CP0232823
4-(3,4-dihydro-1H-thiopyrano[4,3-b]indol-5-ylmethyl)-N-hydroxybenzamide
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C19H18N2O2S
 1
1
IC50 = 398.11 nM
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CP0057110
4-[[butyl(phenylcarbamoyl)amino]methyl]-N-hydroxybenzamide
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C19H23N3O3
 1
1
IC50 = 501.19 nM
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CP0007526
US9249087, 8
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C18H18N2O2
 1
1
IC50 = 630.96 nM
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CP0070180
tert-butyl N-[4-[3-[[7-(hydroxyamino)-7-oxoheptyl]carbamoyl]-1,2-oxazol-5-yl]phenyl]carbamate
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C22H30N4O6
 1
1
IC50 = 794.33 nM
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CP0011676
4-(3,4-dihydro-1H-pyrano[4,3-b]indol-5-ylmethyl)-N-hydroxybenzamide
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C19H18N2O3
 1
1
IC50 = 1000 nM
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CP0003832
N'-hydroxy-N-phenyloctanediamide
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C14H20N2O3
 1
1
IC50 = 1258.93 nM
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CP0004475
RICOLINOSTAT
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C24H27N5O3
 1
1
IC50 = 1584.89 nM
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CP0075287
4-[(2-acetyl-3,4-dihydro-1H-pyrido[4,3-b]indol-5-yl)methyl]-N-hydroxybenzamide
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C21H21N3O3
 1
1
IC50 = 1995.26 nM
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CP0348866
N-hydroxy-4-(1,2,3,4-tetrahydrocarbazol-9-ylmethyl)benzamide
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C20H20N2O2
 1
1
IC50 = 2511.89 nM
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CP0013235
(E)-3-[2-butyl-1-[2-(diethylamino)ethyl]benzimidazol-5-yl]-N-hydroxyprop-2-enamide
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C20H32Cl2N4O2
 1
1
IC50 = 3162.28 nM
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CP0324814
US8748451, 5
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C20H16N2O2
 1
1
IC50 = 3981.07 nM
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CP0014148
N-hydroxy-1-[(4-methoxyphenyl)methyl]indole-6-carboxamide
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C17H16N2O3
 1
1
IC50 > 10000 nM
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CP0238956
4-[(2-tert-butylindol-1-yl)methyl]-N-hydroxybenzamide
   Show/Hide
C20H22N2O2
 1
1
IC50 > 39810.72 nM
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