Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(E)-3-[2-butyl-1-[2-(diethylamino)ethyl]benzimidazol-5-yl]-N-hydroxyprop-2-enamide
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 PubChem ID
CID: 49855250
Canonical SMILES
Cl.Cl.CCCCc1nc2cc(\C=C\C(=O)NO)ccc2n1CCN(CC)CC
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Compound Formula C20H32Cl2N4O2
Compound Structure
Protein Name
 Protein Info 
Polyamine deacetylase HDAC10
Protein Classification
Epigenetic regulator
>
Eraser
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Histone deacetylase
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HDAC class IIb
Uniprot ID
Q969S8
Gene Name
HDAC10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3162.28 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 82 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1584.89 nM
2 Ki = 23 nM