General Information of the Compound
| Compound ID |
CP0013041
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| Compound Name |
HPOB
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| Synonyms |
PMID29671355-Compound-22
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| Structure |
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| Formula |
C17H18N2O4
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| Molecular Weight |
314.341
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| Canonical SMILES |
OCCN(C(=O)Cc1ccc(cc1)C(=O)NO)c1ccccc1
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| InChI |
InChI=1S/C17H18N2O4/c20-11-10-19(15-4-2-1-3-5-15)16(21)12-13-6-8-14(9-7-13)17(22)18-23/h1-9,20,23H,10-12H2,(H,18,22)
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| InChIKey |
RFAZNTABYJYOAR-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00991, Histone deacetylase 1
Protein ID: PT01213, Histone deacetylase 6
Protein ID: PT01443, Polyamine deacetylase HDAC10
Clinical Information about the Compound
Drug 1 ( PMID29671355-Compound-22 )
| Drug Name | PMID29671355-Compound-22 | ||
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| Company | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH BRESLOW, Ronald MARKS, Paul, A | ||
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