Brief Information of the Compound and Protein
Compound Name
3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoyl)phenoxy]ethyl}-1-benzofuran-2-carboxamide
    Show/Hide
PubChem ID
CID: 11749858
SID: 16857486
Canonical SMILES
CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO
    Show/Hide
Compound Formula C21H23N3O5
Compound Structure
Protein Name
Polyamine deacetylase HDAC10
Protein Classification
Epigenetic regulator
>
Eraser
>
Histone deacetylase
>
HDAC class IIb
Uniprot ID
Q969S8
Gene Name
HDAC10
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 7.943 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 3.981 nM
2 IC50 = 52 nM
3 Ki = 20 nM
4 Ki = 24 nM