| Compound ID |
Compound Name |
Compound Formula |
|
CP0372671
|
6-methyl-1-[1-(1-methyl-4-propoxycyclohexyl)piperidin-4-yl]-3H-indol-2-one
Show/Hide
|
C24H36N2O2
|
1
|
| 1 |
EC50 = 63.1 nM
|
|
|
|
CP0388123
|
6-fluoro-5-methyl-3-[1-(1-methyl-4-propoxycyclohexyl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C23H34FN3O2
|
1
|
| 1 |
EC50 = 79.43 nM
|
|
|
|
CP0049755
|
(R)-1-Aza-bicyclo[2.2.2]oct-3-yl-[(Z)-methoxyimino]-acetonitrile
Show/Hide
|
C10H15N3O
|
1
|
| 1 |
EC50 = 117 nM
|
|
|
|
CP0416347
|
CHEMBL1223804
Show/Hide
|
C23H34N2O2
|
1
|
| 1 |
EC50 = 125.89 nM
|
|
|
|
CP0000324
|
2-acetoxyethyl(trimethyl)ammonium;bromide
Show/Hide
|
C7H16NO2+
|
2
|
| 1 |
EC50 = 205 nM
|
|
|
| 2 |
Ki = 7079.46 nM
|
|
|
|
CP0372673
|
CHEMBL1223805
Show/Hide
|
C22H32N2O2
|
1
|
| 1 |
EC50 = 316.23 nM
|
|
|
|
CP0374546
|
CHEMBL1223938
Show/Hide
|
C23H34N2O5S
|
1
|
| 1 |
EC50 = 398.11 nM
|
|
|
|
CP0406096
|
CHEMBL1223940
Show/Hide
|
C23H34N2O4
|
1
|
| 1 |
EC50 = 630.96 nM
|
|
|
|
CP0315086
|
3-chloro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H18ClN3
|
1
|
| 1 |
EC50 = 640 nM
|
|
|
|
CP0128076
|
8-Chloro-11-piperazin-1-yl-5H-dibenzo[b,e][1,4]diazepine
Show/Hide
|
C17H17ClN4
|
1
|
| 1 |
EC50 = 670 nM
|
|
|
|
CP0388126
|
3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-6-fluoro-5-methyl-1,3-benzoxazol-2-one
Show/Hide
|
C22H31FN2O3
|
1
|
| 1 |
EC50 = 794.33 nM
|
|
|
|
CP0374545
|
3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-5-methylsulfonyl-1,3-benzoxazol-2-one
Show/Hide
|
C22H32N2O5S
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
|
CP0372676
|
CHEMBL1223862
Show/Hide
|
C22H32N2O4
|
1
|
| 1 |
EC50 = 1584.89 nM
|
|
|
|
CP0372675
|
CHEMBL1223861
Show/Hide
|
C22H31FN2O3
|
1
|
| 1 |
EC50 = 1995.26 nM
|
|
|
|
CP0388124
|
3-[1-(4-methoxy-1-methylcyclohexyl)piperidin-4-yl]-5-methyl-1,3-benzoxazol-2-one
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
EC50 = 1995.26 nM
|
|
|
|
CP0240069
|
N-ethyl-1-(1H-indazol-5-ylsulfonyl)-N-[[2-(trifluoromethyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
|
C23H25F3N4O3S
|
1
|
| 1 |
EC50 = 2100 nM
|
|
|
|
CP0388743
|
7-chloro-1-(4-(trifluoromethyl)benzyl)indoline-2,3-dione
Show/Hide
|
C16H9ClF3NO2
|
2
|
| 1 |
EC50 = 2200 nM
|
|
|
| 2 |
EC50 = 2220 nM
|
|
|
|
CP0316264
|
6-fluoro-5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C18H24FN3O2
|
1
|
| 1 |
EC50 = 2511.89 nM
|
|
|
|
CP0374543
|
3-[1-(4-ethoxy-1-methylcyclohexyl)piperidin-4-yl]-2-oxo-1,3-benzoxazole-5-carbonitrile
Show/Hide
|
C22H29N3O3
|
1
|
| 1 |
EC50 = 2511.89 nM
|
|
|
|
CP0384743
|
Talsaclidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
EC50 = 2696 nM
|
|
|
|
CP0514870
|
CHEMBL1223939
Show/Hide
|
C23H34N2O5S
|
1
|
| 1 |
EC50 = 3162.28 nM
|
|
|
|
CP0374547
|
3-[1-[4-(2-methoxyethoxy)-1-methylcyclohexyl]piperidin-4-yl]-2-oxo-1,3-benzoxazole-5-carbonitrile
Show/Hide
|
C23H31N3O4
|
1
|
| 1 |
EC50 = 3981.07 nM
|
|
|
|
CP0045829
|
3-(1-cyclohexylpiperidin-4-yl)-1H-benzimidazol-2-one
Show/Hide
|
C18H25N3O
|
1
|
| 1 |
EC50 = 3981.07 nM
|
|
|
|
CP0186462
|
5-methyl-3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C18H25N3O2
|
1
|
| 1 |
EC50 = 3981.07 nM
|
|
|
|
CP0113928
|
1-(4-bromobenzyl)indoline-2,3-dione
Show/Hide
|
C15H10BrNO2
|
2
|
| 1 |
EC50 = 6380 nM
|
|
|
| 2 |
EC50 = 6400 nM
|
|
|
|
CP0400206
|
2-(4-chloro-1,3-thiazol-2-yl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C16H18ClN3OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0045827
|
3-[1-(oxan-4-yl)piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C17H23N3O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0405616
|
2-[(3R,4S)-3-hydroxyoxan-4-yl]-5-methyl-6-[[4-(1,3-oxazol-4-yl)phenyl]methyl]-3H-isoindol-1-one
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0500365
|
5-[[2,6-difluoro-4-(2-methylindazol-4-yl)phenyl]methyl]-1-(oxolan-2-ylmethyl)-4H-pyrrolo[3,4-c]pyrazol-6-one
Show/Hide
|
C25H23F2N5O2
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0557965
|
5-[[2-fluoro-4-(2-methylindazol-5-yl)phenyl]methyl]-4H-pyrrolo[3,4-d][1,3]thiazol-6-one
Show/Hide
|
C20H15FN4OS
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0025667
|
2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl-2,3-dihydro-indol-1-yl)-ethanone
Show/Hide
|
C18H19ClN4
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0189250
|
3-chloro-8-fluoro-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H17ClFN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0450960
|
8-fluoro-3-methyl-6-(1,2,3,6-tetrahydropyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C19H18FN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0533787
|
8-fluoro-3-methyl-6-(1-methyl-3,6-dihydro-2H-pyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C20H20FN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0551894
|
3-chloro-8-fluoro-6-(1,2,3,6-tetrahydropyridin-4-yl)-11H-benzo[b][1,4]benzodiazepine
Show/Hide
|
C18H15ClFN3
|
1
|
| 1 |
EC50 > 10000 nM
|
|
|
|
CP0423460
|
1-[N'-[3-(2-amino-4-methyl-1,3-thiazol-5-yl)propyl]carbamimidoyl]-3-pentylurea
Show/Hide
|
C14H26N6OS
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.12 nM
|
|
|
|
CP0543296
|
1-[(1R)-1-phenylethyl]-3-[N'-[3-(1H-1,2,4-triazol-5-yl)propyl]carbamimidoyl]urea;dihydrochloride
Show/Hide
|
C15H23Cl2N7O
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.12 nM
|
|
|
|
CP0543300
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-benzylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C18H21F6N7O5S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.12 nM
|
|
|
|
CP0551746
|
1-[N'-[3-(5-amino-1,3,4-thiadiazol-2-yl)propyl]carbamimidoyl]-3-pentylurea;2,2,2-trifluoroacetic acid
Show/Hide
|
C16H25F6N7O5S
|
2
|
| 1 |
EC50 > 10000 nM
|
|
|
| 2 |
Kd = 0.12 nM
|
|
|
|
CP0388125
|
CHEMBL1223807
Show/Hide
|
C21H30N2O3
|
1
|
| 1 |
EC50 > 15848.93 nM
|
|
|
|
CP0085573
|
3-[1-[3-(4-fluorophenoxy)propyl]piperidin-4-yl]-1H-benzimidazol-2-one
Show/Hide
|
C21H24FN3O2
|
1
|
| 1 |
EC50 > 25118.86 nM
|
|
|
|
CP0059332
|
1-(4-methoxybenzyl)-5-(trifluoromethoxy)indoline-2,3-dione
Show/Hide
|
C17H12F3NO4
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0168609
|
ethyl 4-[(3R)-3-[(2-methylbenzoyl)amino]piperidin-1-yl]piperidine-1-carboxylate
Show/Hide
|
C21H31N3O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0392295
|
4-[2-(o-toluoylamino)ethylamino]piperidine-1-carboxylic acid ethyl ester;hydrochloride
Show/Hide
|
C18H27N3O3
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0305211
|
1-(1'-(2-methylbenzyl)-1,4'-bipiperidin-4-yl)-1H-benzo[d]imidazol-2(3H)-one
Show/Hide
|
C25H32N4O
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0413445
|
N-benzyl-1-(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)-N-ethylpiperidine-4-carboxamide
Show/Hide
|
C23H28N2O5S
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0412637
|
1-methyl-4-[[6-(1-methylpyrazol-4-yl)pyridin-3-yl]methyl]-N-(oxan-4-yl)pyrrolo[2,3-b]pyridine-6-carboxamide
Show/Hide
|
C24H26N6O2
|
1
|
| 1 |
EC50 > 30000 nM
|
|
|
|
CP0673968
|
SID50106181
Show/Hide
|
C21H26INO2
|
5
|
| 1 |
IC50 = 0.31 nM
|
|
|
| 2 |
IC50 = 0.41 nM
|
|
|
| 3 |
Ki = 0.22 nM
|
|
|
| 4 |
Ki = 0.44 nM
|
|
|
| 5 |
Ki = 0.68 nM
|
|
|
|
CP0918646
|
8,8-dimethyl-3-(thiophen-3-yl-thiophen-3-ylmethyl-carbamoyloxy)-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C19H25BrN2O2S2
|
1
|
| 1 |
IC50 = 1 nM
|
|
|
|
CP0040500
|
3-Hydroxy-2-phenyl-propionic acid 9-methyl-3-oxa-9-aza-tricyclo[3.3.1.0*2,4*]non-7-yl ester
Show/Hide
|
C18H24NO4+
|
2
|
| 1 |
IC50 = 1.1 nM
|
|
|
| 2 |
Ki = 0.1349 nM
|
|
|
|
CP0891440
|
(3S)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-fluorobenzyl)-1-methylpiperidinium
Show/Hide
|
C32H38FIN4O5
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0467374
|
1-[2-(3-chlorophenyl)phenyl]-3-piperidin-4-ylpropan-1-ol
Show/Hide
|
C20H24ClNO
|
1
|
| 1 |
IC50 = 1.995 nM
|
|
|
|
CP0913088
|
3-(benzyl-thiophen-3-yl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C21H27BrN2O2S
|
1
|
| 1 |
IC50 = 2 nM
|
|
|
|
CP0917877
|
8,8-dimethyl-3-(phenyl-thiophen-2-ylmethyl-carbamoyloxy)-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C21H27BrN2O2S
|
1
|
| 1 |
IC50 = 2.3 nM
|
|
|
|
CP0880755
|
8,8-dimethyl-3-(phenyl-thiophen-3-ylmethyl-carbamoyloxy)-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C21H27BrN2O2S
|
1
|
| 1 |
IC50 = 2.8 nM
|
|
|
|
CP0879643
|
3-(benzyl-thiophen-2-yl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C21H27BrN2O2S
|
1
|
| 1 |
IC50 = 3 nM
|
|
|
|
CP0481466
|
3-[(4-methylpiperazin-1-yl)methyl]-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C31H39N5O
|
1
|
| 1 |
IC50 = 3.981 nM
|
|
|
|
CP0854409
|
3-(benzyl-phenyl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C23H29BrN2O2
|
1
|
| 1 |
IC50 = 4.6 nM
|
|
|
|
CP0391914
|
propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-(1,2,3,4-tetrahydronaphthalen-2-ylmethyl)piperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C42H48ClN4O5+
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0391915
|
(4-chlorophenyl)methyl-[3-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]-2,2-dimethylpropyl]-dimethylazanium
Show/Hide
|
C34H44ClN4O5+
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0395561
|
propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[4-methyl-4-(2-phenylethyl)piperazin-4-ium-1-yl]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C33H41N4O5+
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0414826
|
propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-(cyclohexylmethyl)piperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C38H48ClN4O5+
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0848260
|
(S)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-3,7-dimethyl-7H-imidazo[2,1-b]thiazol-4-ium
Show/Hide
|
C28H32N5O5S+
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0856414
|
(S)-7-(4-chlorobenzyl)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-3-methyl-7H-imidazo[2,1-b]thiazol-4-ium
Show/Hide
|
C34H35ClN5O5S+
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0935330
|
(S)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-2,7-dimethyl-7H-imidazo[2,1-b]thiazol-4-ium
Show/Hide
|
C28H32N5O5S+
|
1
|
| 1 |
IC50 < 5 nM
|
|
|
|
CP0398626
|
propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0399963
|
N-[[3-[3-[[(3S)-3-methylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
IC50 = 5.012 nM
|
|
|
|
CP0408782
|
1-adamantyl-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]-dimethylazanium
Show/Hide
|
C34H47N4O5+
|
1
|
| 1 |
IC50 = 6.1 nM
|
|
|
|
CP0440676
|
ethyl 4-[[(2S)-1-[[1-[(3-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H33N5O5
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0891438
|
(3S)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-hydroxybenzyl)-1-methylpyrrolidinium
Show/Hide
|
C31H37IN4O6
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0894403
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C32H37IN4O7
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0916599
|
(3S)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-fluorobenzyl)-1-methylpyrrolidinium
Show/Hide
|
C31H36FIN4O5
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0455293
|
N-[[4-fluoro-3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C26H26FN3O3
|
1
|
| 1 |
IC50 = 6.31 nM
|
|
|
|
CP0844749
|
8,8-dimethyl-3-[(3-methyl-thiophen-2-ylmethyl)-phenyl-carbamoyloxy]-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C22H29BrN2O2S
|
1
|
| 1 |
IC50 = 6.4 nM
|
|
|
|
CP0854410
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl thiophen-3-yl(thiophen-3-ylmethyl)carbamate
Show/Hide
|
C18H22N2O2S2
|
1
|
| 1 |
IC50 = 7.2 nM
|
|
|
|
CP0493289
|
ethyl 4-[[(2S)-1-[[1-[(3-chlorophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H33ClN4O5
|
1
|
| 1 |
IC50 = 7.943 nM
|
|
|
|
CP0928833
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(3-chlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
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C32H36ClIN4O6
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1
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| 1 |
IC50 = 7.943 nM
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CP0481463
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propyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
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C31H36N4O6
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1
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| 1 |
IC50 = 10 nM
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CP0904301
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-chlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
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C32H36ClIN4O6
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1
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| 1 |
IC50 = 10 nM
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CP0399235
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N-[[3-[3-[(3-methylpiperazin-1-yl)methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
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C27H29N3O3
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1
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| 1 |
IC50 = 10 nM
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CP0399241
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3-ethoxy-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
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C27H31N3O2
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1
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| 1 |
IC50 = 10 nM
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CP0528346
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3-acetyl-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
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C27H29N3O2
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1
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| 1 |
IC50 = 10 nM
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CP0847624
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2-(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1,1-diphenylethanol
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C22H27NO
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 2.512 nM
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| 3 |
Ki = 1.995 nM
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CP0858919
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(3-endo)-3-(3-Hydroxy-2,2-diphenylpropyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
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C24H32BrNO
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4
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 3.162 nM
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| 3 |
Kd = 3.981 nM
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| 4 |
Ki = 2.512 nM
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CP0858933
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3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropanenitrile
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C23H26N2
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4
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.0631 nM
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| 3 |
Kd = 0.3162 nM
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| 4 |
Ki = 0.1585 nM
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CP0867929
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(3-endo)-3-(2-Cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
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C24H29BrN2
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4
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.01995 nM
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| 3 |
Ki = 0.06 nM
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| 4 |
Ki = 0.0631 nM
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CP0870156
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3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenyl-1-propanol
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C23H29NO
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 3.981 nM
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| 3 |
Ki = 2.512 nM
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CP0906476
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endo-3-(2-hydroxy-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
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C23H30BrNO
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.5012 nM
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| 3 |
Ki = 3.162 nM
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CP0845829
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(3-endo)-3-(2-Hydroxy-2,2-diphenylethyl)-9,9-dimethyl-9-azoniabicyclo[3.3.1]nonane Bromide
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C24H32BrNO
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 1.585 nM
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CP0846160
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(3-endo)-3-(2-Carbamoyl-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Iodide
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C24H31IN2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.1259 nM
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CP0894658
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(3-endo)-3-(2,2-Di-2-thienylethenyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
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C19H24BrNS2
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.1 nM
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| 3 |
Ki = 0.45 nM
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CP0903853
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3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropanamide
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C23H28N2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.1 nM
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CP0906475
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endo-3-(2,2-diphenylvinyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
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C23H28BrN
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 5.012 nM
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CP0906708
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2-(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1,1-di(thiophen-2-yl)ethanol
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C18H23NOS2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 2.512 nM
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CP0906847
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(3-endo)-3-(2,2-Di-2-thienylethenyl)-9,9-dimethyl-9-azoniabicyclo[3.3.1]nonane Bromide
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C20H26BrNS2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 1 nM
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CP0911928
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(3-endo)-3-[2-Hydroxy-2,2-bis(2-methylphenyl)ethyl]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
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C25H34BrNO
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2
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| 1 |
IC50 = 10 nM
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| 2 |
Kd = 5.012 nM
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CP0911929
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(3-endo)-3-[2,2-Bis(2-methylphenyl)ethenyl]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
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C25H32BrN
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.1 nM
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CP0917537
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(3-endo)-3-(2-Hydroxy-2,2-di-2-thienylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
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C19H26BrNOS2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 2.512 nM
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CP0919893
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(3-endo)-3-(2-Hydroxy-2,2-di-2-thienylethyl)-9,9-dimethyl-9-azoniabicyclo[3.3.1]nonane Iodide
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C20H28INOS2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 1.995 nM
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CP0459259
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3-(8-hex-5-enyl-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl)-2,2-diphenylpropanenitrile
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C29H37N2+
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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CP0871809
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3-(2-cyano-2,2-diphenylethyl)-8-(3-cyanopropyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C27H32BrN3
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.1585 nM
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CP0873402
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3-(2-cyano-2,2-diphenylethyl)-8-ethyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C25H31BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.05012 nM
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CP0873403
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N-Endo-8-(3-(benzyloxy)propyl)-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C33H39BrN2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.03981 nM
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CP0873786
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3-(2-cyano-2,2-diphenylethyl)-8-(2-methoxyethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C26H33BrN2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.5012 nM
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CP0873788
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-octyl-8-azoniabicyclo[3.2.1]octane bromide
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C31H43BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.07943 nM
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CP0882308
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-(3-phenoxypropyl)-8-azoniabicyclo[3.2.1]octane bromide
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C32H37BrN2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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CP0885279
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3-(2-cyano-2,2-diphenylethyl)-8-(cyclopropylmethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C27H33BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.05012 nM
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CP0885280
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8-allyl-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane iodide
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C26H31IN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 1.259 nM
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CP0887432
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-(2-phenoxyethyl)-8-azoniabicyclo[3.2.1]octane bromide
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C31H35BrN2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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CP0894256
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3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-propyl-8-azoniabicyclo[3.2.1]octane bromide
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C26H33BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.05012 nM
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CP0895524
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N-Endo-8-butyl-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C27H35BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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CP0895525
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3-(2-cyano-2,2-diphenylethyl)-8-(2-hydroxyethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C25H31BrN2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.1585 nM
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CP0895526
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N-Endo-8-(2-(benzyloxy)ethyl)-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane iodide
Show/Hide
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C32H37IN2O
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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CP0895527
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-hexyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C29H39BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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CP0895929
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-(cyclopropylmethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C27H33BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.02512 nM
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CP0895932
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-(hex-5-enyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C29H37BrN2
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3
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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| 3 |
Ki = 0.16 nM
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CP0913688
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3-(2-cyano-2,2-diphenylethyl)-8-(2-(2-methoxyethoxy)ethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
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C28H37BrN2O2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd = 0.631 nM
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CP0935242
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N-Endo-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-(3-phenylpropyl)-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
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C32H37BrN2
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2
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| 1 |
IC50 < 10 nM
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| 2 |
Kd < 0.01 nM
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CP0423461
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propan-2-yl 4-[[(2S)-1-[4-(1,3-benzodioxol-5-ylmethyl)-4-methylpiperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C33H39N4O7+
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1
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| 1 |
IC50 = 10.2 nM
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CP0879640
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thiophen-3-yl)carbamate
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C20H24N2O2S
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1
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| 1 |
IC50 = 10.9 nM
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CP0903851
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(3-endo)-1,1-Bis-(3-fluorophenyl)-2-(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl)ethanol Iodide
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|
C23H28F2INO
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2
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| 1 |
IC50 = 11 nM
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| 2 |
Kd = 10 nM
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CP0913094
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3-(cyclohexylmethyl-thiophen-3-yl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
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C21H33BrN2O2S
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1
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| 1 |
IC50 = 11.3 nM
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CP0858371
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-bromophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C32H36BrIN4O6
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1
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| 1 |
IC50 = 12.59 nM
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CP0914882
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-benzoylphenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C39H41IN4O7
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1
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| 1 |
IC50 = 12.59 nM
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CP0405983
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4-[(E)-3-[2-(3-chlorophenyl)phenyl]prop-2-enyl]piperidine
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C20H22ClN
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1
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| 1 |
IC50 = 12.59 nM
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CP0452476
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(4-chlorophenyl)methyl-[(3R)-1-[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]piperidin-3-yl]-dimethylazanium
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C34H42ClN4O5+
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1
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| 1 |
IC50 = 13.3 nM
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CP0388598
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[(3S)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O6
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1
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| 1 |
IC50 = 15.85 nM
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CP0440679
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ethyl 4-[[(2S)-1-[(1-benzylpyrrolidin-3-yl)amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O5
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1
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| 1 |
IC50 = 15.85 nM
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CP0503050
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-oxo-1-[[1-[[3-(trifluoromethyl)phenyl]methyl]pyrrolidin-3-yl]amino]propan-2-yl]carbamoylamino]benzoate
Show/Hide
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C31H33F3N4O5
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1
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| 1 |
IC50 = 15.85 nM
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CP0867851
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-fluorophenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
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C32H36FIN4O6
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1
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| 1 |
IC50 = 15.85 nM
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CP0867852
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-p-tolylpropanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H39IN4O6
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1
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| 1 |
IC50 = 15.85 nM
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CP0894395
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(3S)-3-((S)-3-(4-aminophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-1-methylpyrrolidinium
Show/Hide
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C32H38IN5O6
|
1
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| 1 |
IC50 = 15.85 nM
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CP0919122
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(biphenyl-4-yl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C38H41IN4O6
|
1
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| 1 |
IC50 = 15.85 nM
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CP0913085
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3-(furan-3-ylmethyl-phenyl-carbamoyloxy)-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
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|
C21H27BrN2O3
|
1
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| 1 |
IC50 = 16 nM
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CP0920112
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(3-endo)-1,1-Bis-(3-thienyl)-2-(8,8-dimethyl-8-azoniabicyclo-[3.2.1]oct-3-yl)ethanol Iodide
Show/Hide
|
C19H26INOS2
|
1
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| 1 |
IC50 = 17 nM
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CP0941534
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2-(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1-phenyl-1-(pyridin-2-yl)ethanol
Show/Hide
|
C21H26N2O
|
1
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| 1 |
IC50 = 19 nM
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CP0440677
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
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| 1 |
IC50 = 19.95 nM
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CP0522818
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(3-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O6
|
1
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| 1 |
IC50 = 19.95 nM
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CP0858376
|
Ethyl 4-[({[(1S)-1-[(4-hydroxyphenyl)methyl]-2-({1-[(4-hydroxyphenyl)methyl]-3-pyrrolidinyl}amino)-2-oxoethyl]amino}carbonyl)amino]benzoate
Show/Hide
|
C30H34N4O6
|
1
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| 1 |
IC50 = 19.95 nM
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CP0503065
|
methyl 3-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methylcarbamoyl]benzoate
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0525997
|
3-methylsulfonyl-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H29N3O3S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0417830
|
4-[2-[2-(3-chlorophenyl)phenyl]sulfonylethyl]piperidine
Show/Hide
|
C19H22ClNO2S
|
1
|
| 1 |
IC50 = 19.95 nM
|
|
|
|
CP0879642
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl phenyl(thiophen-2-ylmethyl)carbamate
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
IC50 = 20.3 nM
|
|
|
|
CP0920181
|
8,8-dimethyl-3-[(5-methyl-thiophen-2-ylmethyl)-phenyl-carbamoyloxy]-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C22H29BrN2O2S
|
1
|
| 1 |
IC50 = 21.2 nM
|
|
|
|
CP0918645
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(thiophen-2-yl)carbamate
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
IC50 = 22.9 nM
|
|
|
|
CP0894657
|
(3-endo)-3-[2-Hydroxy-2,2-bis(2-methylphenyl)ethyl]-9,9-dimethyl-9-azoniabicyclo[3.3.1]nonane Iodide
Show/Hide
|
C26H36INO
|
1
|
| 1 |
IC50 = 23 nM
|
|
|
|
CP0907717
|
(3-endo)-3-[2,2-Bis(3-chlorophenyl)-2-hydroxyethyl]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Iodide
Show/Hide
|
C23H28Cl2INO
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0474371
|
methyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C29H32N4O6
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0493287
|
ethyl 4-[[(2S)-1-[[1-(cyclopropylmethyl)pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C27H34N4O5
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0503049
|
ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(3-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0858375
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(3,4-dichlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C32H35Cl2IN4O6
|
1
|
| 1 |
IC50 = 25.12 nM
|
|
|
|
CP0857826
|
1-Cyclohexyl-1-phenyl-3-piperidin-1-yl-propan-1-ol hydrochloride
Show/Hide
|
C20H32ClNO
|
1
|
| 1 |
IC50 = 26.3 nM
|
|
|
|
CP0461369
|
3-[8-(cyclopropylmethyl)-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl]-2,2-diphenylpropanenitrile
Show/Hide
|
C27H33N2+
|
1
|
| 1 |
IC50 = 26.3 nM
|
|
|
|
CP0920525
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl phenyl(thiophen-3-ylmethyl)carbamate
Show/Hide
|
C20H24N2O2S
|
1
|
| 1 |
IC50 = 27.5 nM
|
|
|
|
CP0423465
|
propan-2-yl 4-[[(2S)-1-[4-[(4-chlorophenyl)methyl]-4-propan-2-ylpiperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C34H42ClN4O5+
|
1
|
| 1 |
IC50 = 27.5 nM
|
|
|
|
CP0484598
|
N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C26H27N3O3
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0417386
|
ethyl 4-[[(2S)-1-[[1-(1,3-benzodioxol-5-ylmethyl)pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H34N4O7
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0914881
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-(trifluoromethyl)phenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H36F3IN4O6
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0532028
|
N-[[4-methoxy-3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H29N3O4
|
1
|
| 1 |
IC50 = 31.62 nM
|
|
|
|
CP0513453
|
3-(8-hex-5-enyl-8-methyl-8-azoniabicyclo[3.2.1]octan-3-yl)-2,2-diphenylpropanenitrile
Show/Hide
|
C29H37N2+
|
1
|
| 1 |
IC50 = 32 nM
|
|
|
|
CP0399182
|
propan-2-yl 4-[[(2S)-1-[2-[1-[(4-chlorophenyl)methyl]piperidin-1-ium-1-yl]ethylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C34H42ClN4O5+
|
1
|
| 1 |
IC50 = 33.4 nM
|
|
|
|
CP0919891
|
(3-endo)-1,1-Bis(5-fluoro-2-methylphenyl)-2-(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl)ethanol Bromide
Show/Hide
|
C25H32BrF2NO
|
1
|
| 1 |
IC50 = 37 nM
|
|
|
|
CP0869979
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)-3-(4-methoxyphenyl)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H39IN4O7
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0891032
|
(S)-N-(3-(6-((3-methylpiperazin-1-yl)methyl)pyridin-2-yl)benzyl)benzo[d][1,3]dioxole-5-carboxamide
Show/Hide
|
C26H28N4O3
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0405990
|
2-(3-chlorophenyl)-6-fluoro-N-[[(3R,4S)-3-methylpiperidin-4-yl]methyl]benzamide
Show/Hide
|
C20H22ClFN2O
|
1
|
| 1 |
IC50 = 39.81 nM
|
|
|
|
CP0854268
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
|
C22H29NO6
|
1
|
| 1 |
IC50 = 40.8 nM
|
|
|
|
CP0913098
|
8,8-dimethyl-3-[(3-methyl-furan-2-ylmethyl)-phenyl-carbamoyloxy]-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C22H29BrN2O3
|
1
|
| 1 |
IC50 = 42.3 nM
|
|
|
|
CP0499985
|
propan-2-yl 4-[[(2S)-1-[2-[1-[(4-chlorophenyl)methyl]pyrrolidin-1-ium-1-yl]ethylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C33H40ClN4O5+
|
1
|
| 1 |
IC50 = 44.9 nM
|
|
|
|
CP0430238
|
(4-chlorophenyl)methyl-[(3S)-1-[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]piperidin-3-yl]-dimethylazanium
Show/Hide
|
C34H42ClN4O5+
|
1
|
| 1 |
IC50 = 45.3 nM
|
|
|
|
CP0493290
|
ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(2-methoxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H36N4O6
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0858370
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(4-cyanophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C33H36IN5O6
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0460424
|
N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-3-(trifluoromethyl)benzamide
Show/Hide
|
C26H26F3N3O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0503062
|
3-cyano-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H26N4O
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0529517
|
N-[[3-[3-[[(3R)-3-methylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
IC50 = 50.12 nM
|
|
|
|
CP0395563
|
propan-2-yl 4-[[(2S)-1-[4-(cyclohexylmethyl)-4-methylpiperazin-4-ium-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C32H45N4O5+
|
1
|
| 1 |
IC50 = 50.2 nM
|
|
|
|
CP0480882
|
propan-2-yl 4-[[(2S)-1-[[1,3-bis[(4-chlorophenyl)methyl]imidazol-1-ium-2-yl]methylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C38H38Cl2N5O5+
|
1
|
| 1 |
IC50 = 51.9 nM
|
|
|
|
CP0873209
|
3-[(4-bromo-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C23H28Br2N2O2
|
1
|
| 1 |
IC50 = 56.6 nM
|
|
|
|
CP0916155
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl furan-3-ylmethyl(phenyl)carbamate
Show/Hide
|
C20H24N2O3
|
1
|
| 1 |
IC50 = 57.3 nM
|
|
|
|
CP0873800
|
3-(2-cyano-2,2-diphenylethyl)-8-dodecyl-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
|
C35H51BrN2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0894656
|
(3-endo)-1,1-Bis(3-fluoro-2-methylphenyl)-2-(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl)ethanol Bromide
Show/Hide
|
C25H32BrF2NO
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0909066
|
(3-endo)-3-[2-Hydroxy-2,2-bis(4-methyl-3-thienyl)ethyl]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
Show/Hide
|
C21H30BrNOS2
|
1
|
| 1 |
IC50 = 65 nM
|
|
|
|
CP0391917
|
propan-2-yl 4-[[(2S)-1-[4-[1-[(4-chlorophenyl)methyl]pyrrolidin-1-ium-1-yl]piperidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C36H44ClN4O5+
|
1
|
| 1 |
IC50 = 68.9 nM
|
|
|
|
CP0523854
|
bis[(4-chlorophenyl)methyl]-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]-methylazanium
Show/Hide
|
C37H41Cl2N4O5+
|
1
|
| 1 |
IC50 = 70.4 nM
|
|
|
|
CP0903852
|
(3-endo)-1,1-Bis-(4-chlorophenyl)-2-(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl)ethanol Iodide
Show/Hide
|
C23H28Cl2INO
|
1
|
| 1 |
IC50 = 74 nM
|
|
|
|
CP0854413
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl benzyl(phenyl)carbamate
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
IC50 = 74.5 nM
|
|
|
|
CP0464265
|
N-[[3-[3-[[(1S,4S)-2,5-diazabicyclo[2.2.1]heptan-2-yl]methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H27N3O3
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0503063
|
4-cyano-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H26N4O
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0503064
|
3-methoxy-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H29N3O2
|
1
|
| 1 |
IC50 = 79.43 nM
|
|
|
|
CP0423458
|
2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl-methyl-bis(naphthalen-2-ylmethyl)azanium
Show/Hide
|
C45H47N4O5+
|
1
|
| 1 |
IC50 = 82.2 nM
|
|
|
|
CP0935241
|
3-(2-cyano-2,2-diphenylethyl)-8-(hex-5-enyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
|
C29H37BrN2
|
1
|
| 1 |
IC50 = 85.2 nM
|
|
|
|
CP0850038
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid octyl ester oxalic acid
Show/Hide
|
C24H35NO6
|
1
|
| 1 |
IC50 = 86.5 nM
|
|
|
|
CP0847735
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-p-tolyl-ethyl ester oxalic acid
Show/Hide
|
C25H29NO6
|
1
|
| 1 |
IC50 = 88.3 nM
|
|
|
|
CP0873787
|
3-(2-cyano-2,2-diphenylethyl)-8-(cyclohexylmethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
|
C30H39BrN2
|
1
|
| 1 |
IC50 = 89.6 nM
|
|
|
|
CP0422304
|
cyclopropylmethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C32H36N4O6
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0459567
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-propan-2-ylbenzamide
Show/Hide
|
C32H36N6O4
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0486398
|
3-chloro-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C25H26ClN3O
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0847169
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
|
C24H27NO6
|
1
|
| 1 |
IC50 = 100.7 nM
|
|
|
|
CP0881236
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (3-methylthiophen-2-yl)methyl(phenyl)carbamate
Show/Hide
|
C21H26N2O2S
|
1
|
| 1 |
IC50 = 108 nM
|
|
|
|
CP0844748
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl cyclohexylmethyl(thiophen-3-yl)carbamate
Show/Hide
|
C20H30N2O2S
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0938998
|
3-(2-cyano-2,2-diphenylethyl)-8-(2-cyclohexylethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
|
C31H41BrN2
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0860558
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid cyclohexylmethyl ester oxalic acid
Show/Hide
|
C23H31NO6
|
1
|
| 1 |
IC50 = 109.6 nM
|
|
|
|
CP0919892
|
(3-endo)-3-[2,2-Bis(3,5-difluorophenyl)-2-hydroxyethyl]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
Show/Hide
|
C23H26BrF4NO
|
1
|
| 1 |
IC50 = 112 nM
|
|
|
|
CP0869657
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-cyclohexyl-ethyl ester oxalic acid
Show/Hide
|
C24H33NO6
|
1
|
| 1 |
IC50 = 114.7 nM
|
|
|
|
CP0914880
|
(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(2-chlorophenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
|
C32H36ClIN4O6
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0405985
|
2-[2-(3-chlorophenyl)phenyl]-N-piperidin-4-ylacetamide
Show/Hide
|
C19H21ClN2O
|
1
|
| 1 |
IC50 = 125.89 nM
|
|
|
|
CP0935632
|
3-(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-1,1-diphenylpropan-1-ol
Show/Hide
|
C23H29NO
|
1
|
| 1 |
IC50 = 134 nM
|
|
|
|
CP0920239
|
1-(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-2-phenylbutan-2-ol
Show/Hide
|
C18H27NO
|
1
|
| 1 |
IC50 = 135 nM
|
|
|
|
CP0896081
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-cyanobenzyl(thiophen-3-yl)carbamate
Show/Hide
|
C21H23N3O2S
|
1
|
| 1 |
IC50 = 136.9 nM
|
|
|
|
CP0854414
|
3-[(3-cyano-benzyl)-thiophen-3-yl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C22H26BrN3O2S
|
1
|
| 1 |
IC50 = 137.4 nM
|
|
|
|
CP0447892
|
(4-chlorophenyl)methyl-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]-dimethylazanium
Show/Hide
|
C31H38ClN4O5+
|
1
|
| 1 |
IC50 = 142.6 nM
|
|
|
|
CP0896083
|
3-[(4-methoxy-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C24H31BrN2O3
|
1
|
| 1 |
IC50 = 154.4 nM
|
|
|
|
CP0845078
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid cyclohexylmethyl ester oxalic acid
Show/Hide
|
C23H31NO6
|
1
|
| 1 |
IC50 = 155.8 nM
|
|
|
|
CP0459569
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-(cyclopropylmethyl)benzamide
Show/Hide
|
C33H36N6O4
|
1
|
| 1 |
IC50 = 158.49 nM
|
|
|
|
CP0430242
|
propan-2-yl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[2-(1-methylazepan-1-ium-1-yl)ethylamino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C29H41N4O5+
|
1
|
| 1 |
IC50 = 158.9 nM
|
|
|
|
CP0886216
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid heptyl ester oxalic acid
Show/Hide
|
C23H33NO6
|
1
|
| 1 |
IC50 = 162.5 nM
|
|
|
|
CP0391918
|
(4-chlorophenyl)methyl-[3-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]propyl]-dimethylazanium
Show/Hide
|
C32H40ClN4O5+
|
1
|
| 1 |
IC50 = 197.3 nM
|
|
|
|
CP0388481
|
3-acetamido-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0399236
|
N-[[3-[4-fluoro-3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C26H26FN3O3
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0525998
|
3-(dimethylamino)-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C27H32N4O
|
1
|
| 1 |
IC50 = 199.53 nM
|
|
|
|
CP0404712
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester
Show/Hide
|
C23H35NO2
|
1
|
| 1 |
IC50 = 201.6 nM
|
|
|
|
CP0920358
|
(3-endo)-8-Methyl-3-(2,2,2-triphenylethyl)-8-azabicyclo[3.2.1]-octane
Show/Hide
|
C28H31N
|
1
|
| 1 |
IC50 = 206 nM
|
|
|
|
CP0854470
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid benzyl ester hydrochloride
Show/Hide
|
C21H24ClNO2
|
1
|
| 1 |
IC50 = 211.3 nM
|
|
|
|
CP0878820
|
(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
|
C22H33NO6
|
1
|
| 1 |
IC50 = 220.3 nM
|
|
|
|
CP0408783
|
(4-chlorophenyl)methyl-diethyl-[2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl]azanium
Show/Hide
|
C33H42ClN4O5+
|
1
|
| 1 |
IC50 = 223.2 nM
|
|
|
|
CP0376700
|
2-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl-methyl-di(propan-2-yl)azanium
Show/Hide
|
C29H43N4O5+
|
1
|
| 1 |
IC50 = 237 nM
|
|
|
|
CP0398628
|
2-methylpropyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C32H38N4O6
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0399237
|
N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-sulfonamide
Show/Hide
|
C25H27N3O4S
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0417589
|
N-[[2-fluoro-5-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C26H26FN3O3
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0460426
|
3-methyl-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H29N3O
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0473116
|
2-(3-chloro-4-methylphenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C20H23ClN2O
|
1
|
| 1 |
IC50 = 251.19 nM
|
|
|
|
CP0847343
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid isobutyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 257.5 nM
|
|
|
|
CP0913092
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (5-methylthiophen-2-yl)methyl(phenyl)carbamate
Show/Hide
|
C21H26N2O2S
|
1
|
| 1 |
IC50 = 261.6 nM
|
|
|
|
CP0849749
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid butyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0907718
|
(3-endo)-1,1-Bis(3,4-difluorophenyl)-2-(8,8-dimethyl-8-azoniabicyclo[3.2.1]oct-3-yl)ethanol Bromide
Show/Hide
|
C23H26BrF4NO
|
1
|
| 1 |
IC50 = 290 nM
|
|
|
|
CP0849760
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
|
C22H29NO6
|
1
|
| 1 |
IC50 = 299.3 nM
|
|
|
|
CP0861085
|
1-Ethyl-4-phenyl-piperidine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
|
C24H29NO6
|
1
|
| 1 |
IC50 = 315.4 nM
|
|
|
|
CP0474370
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-ethylbenzamide
Show/Hide
|
C31H34N6O4
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0460423
|
2-cyano-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H26N4O
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0503061
|
N-[[3-[4-methoxy-3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H29N3O4
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0503066
|
3-ethyl-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C27H31N3O
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0526769
|
N-[[3-[3-(1,4-diazepan-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0528345
|
4-chloro-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C25H26ClN3O
|
1
|
| 1 |
IC50 = 316.23 nM
|
|
|
|
CP0875555
|
8-benzyl-3-(2-cyano-2,2-diphenylethyl)-8-methyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
|
C30H33BrN2
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0054849
|
(3S,3aR,4R,4aS,8aR,9aS)-3-Methyl-4-[2-((R)-1-methyl-6-(S)-methyl-piperidin-2-yl)-vinyl]-decahydro-naphtho[2,3-c]furan-1-one
Show/Hide
|
C22H35NO2
|
2
|
| 1 |
IC50 = 333.6 nM
|
|
|
| 2 |
Ki = 93.33 nM
|
|
|
|
CP0913086
|
3-[(3-bromo-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C23H28Br2N2O2
|
1
|
| 1 |
IC50 = 342.1 nM
|
|
|
|
CP0878826
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
|
C22H31NO6
|
1
|
| 1 |
IC50 = 349 nM
|
|
|
|
CP0860587
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid pentyl ester oxalic acid
Show/Hide
|
C21H29NO6
|
1
|
| 1 |
IC50 = 356.9 nM
|
|
|
|
CP0389549
|
[1-[6-(4-chlorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C25H25ClN4O2
|
1
|
| 1 |
IC50 = 365 nM
|
|
|
|
CP0389547
|
[1-[6-(2,4-difluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(3,4-dihydro-1H-isoquinolin-2-yl)methanone
Show/Hide
|
C25H24F2N4O2
|
1
|
| 1 |
IC50 = 380 nM
|
|
|
|
CP0499982
|
propan-2-yl 4-[[(2S)-1-[[1-[(4-chlorophenyl)methyl]-3-methylimidazol-3-ium-2-yl]methyl-methylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C33H37ClN5O5+
|
1
|
| 1 |
IC50 = 392.4 nM
|
|
|
|
CP0455901
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N,N-diethylbenzamide
Show/Hide
|
C33H38N6O4
|
1
|
| 1 |
IC50 = 398.11 nM
|
|
|
|
CP0392493
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid decyl ester
Show/Hide
|
C24H37NO2
|
1
|
| 1 |
IC50 = 399.5 nM
|
|
|
|
CP0870135
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid benzyl ester hydrochloride
Show/Hide
|
C21H24ClNO2
|
1
|
| 1 |
IC50 = 403.6 nM
|
|
|
|
CP0389544
|
3,4-dihydro-1H-isoquinolin-2-yl-[1-[6-(2-fluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]methanone
Show/Hide
|
C25H25FN4O2
|
1
|
| 1 |
IC50 = 404 nM
|
|
|
|
CP0854411
|
3-[(2-bromo-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C23H28Br2N2O2
|
1
|
| 1 |
IC50 = 407.2 nM
|
|
|
|
CP0391919
|
3-[[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]propyl-dimethyl-(naphthalen-2-ylmethyl)azanium
Show/Hide
|
C36H43N4O5+
|
1
|
| 1 |
IC50 = 417.1 nM
|
|
|
|
CP0896082
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl (3-methylfuran-2-yl)methyl(phenyl)carbamate
Show/Hide
|
C21H26N2O3
|
1
|
| 1 |
IC50 = 428.3 nM
|
|
|
|
CP0845389
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 5-phenyl-pentyl ester oxalic acid
Show/Hide
|
C27H33NO6
|
1
|
| 1 |
IC50 = 447.9 nM
|
|
|
|
CP0398625
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-phenylbenzamide
Show/Hide
|
C35H34N6O4
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0493286
|
4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-propylbenzamide
Show/Hide
|
C32H36N6O4
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0399240
|
N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-3-(trifluoromethoxy)benzamide
Show/Hide
|
C26H26F3N3O2
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0399961
|
N-[[3-[3-[(4-methylpiperazin-1-yl)methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0506336
|
4-methoxy-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H29N3O2
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0529518
|
2-methoxy-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C26H29N3O2
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0867928
|
(S)-N-(3-(5-((3-methylpiperazin-1-yl)methyl)thiophen-2-yl)benzyl)benzo[d][1,3]dioxole-5-carboxamide
Show/Hide
|
C25H27N3O3S
|
1
|
| 1 |
IC50 = 501.19 nM
|
|
|
|
CP0859753
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-cyclohexyl-ethyl ester oxalic acid
Show/Hide
|
C24H33NO6
|
1
|
| 1 |
IC50 = 529.6 nM
|
|
|
|
CP0869546
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid butyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 535.5 nM
|
|
|
|
CP0395558
|
propan-2-yl 4-[[(2S)-1-[4-(1-ethylpyrrolidin-1-ium-1-yl)piperidin-1-yl]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C31H43N4O5+
|
1
|
| 1 |
IC50 = 579.3 nM
|
|
|
|
CP0399239
|
N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-4-(trifluoromethyl)benzamide
Show/Hide
|
C26H26F3N3O
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0526770
|
N-[[3-[3-[(4-methyl-1,4-diazepan-1-yl)methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C28H31N3O3
|
1
|
| 1 |
IC50 = 630.96 nM
|
|
|
|
CP0356645
|
[1-[6-(2,4-difluorophenoxy)pyrimidin-4-yl]piperidin-4-yl]-(1,3-dihydroisoindol-2-yl)methanone
Show/Hide
|
C24H22F2N4O2
|
1
|
| 1 |
IC50 = 660 nM
|
|
|
|
CP0914612
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid octyl ester oxalic acid
Show/Hide
|
C24H35NO6
|
1
|
| 1 |
IC50 = 675.6 nM
|
|
|
|
CP0889381
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid propyl ester oxalic acid
Show/Hide
|
C19H25NO6
|
1
|
| 1 |
IC50 = 684 nM
|
|
|
|
CP0903854
|
3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropanoic Acid
Show/Hide
|
C23H27NO2
|
1
|
| 1 |
IC50 = 687 nM
|
|
|
|
CP0854408
|
3-[(4-cyano-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C24H28BrN3O2
|
1
|
| 1 |
IC50 = 713.9 nM
|
|
|
|
CP0873200
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-bromobenzyl(phenyl)carbamate
Show/Hide
|
C22H25BrN2O2
|
1
|
| 1 |
IC50 = 720.7 nM
|
|
|
|
CP0853934
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 3-phenyl-propyl ester hydrochloride
Show/Hide
|
C23H28ClNO2
|
1
|
| 1 |
IC50 = 749.3 nM
|
|
|
|
CP0913087
|
8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-methoxybenzyl(phenyl)carbamate
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
IC50 = 776.3 nM
|
|
|
|
CP0456704
|
4-[4-[6-(3,3-dimethylpiperidin-1-yl)pyridazin-3-yl]piperazin-1-yl]sulfonyl-3,5-dimethyl-1,2-oxazole
Show/Hide
|
C20H30N6O3S
|
1
|
| 1 |
IC50 = 782 nM
|
|
|
|
CP0493288
|
ethyl 4-[[(2S)-1-[(1-ethylpyrrolidin-3-yl)amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C25H32N4O5
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0460425
|
3-fluoro-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
|
C25H26FN3O
|
1
|
| 1 |
IC50 = 794.33 nM
|
|
|
|
CP0858934
|
3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenyl-N-(phenylmethyl)propanamide
Show/Hide
|
C30H34N2O
|
1
|
| 1 |
IC50 = 839 nM
|
|
|
|
CP0863347
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid isobutyl ester oxalic acid
Show/Hide
|
C20H27NO6
|
1
|
| 1 |
IC50 = 844.6 nM
|
|
|
|
CP0886217
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2,2-diphenyl-ethyl ester oxalic acid
Show/Hide
|
C30H31NO6
|
1
|
| 1 |
IC50 = 871.1 nM
|
|
|
|
CP0635477
|
(2-Carbamoyloxy-ethyl)-trimethyl-ammonium chloride
Show/Hide
|
C6H15ClN2O2
|
2
|
| 1 |
IC50 = 880 nM
|
|
|
| 2 |
Ki = 43651.58 nM
|
|
|
|
CP0854465
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid pentyl ester oxalic acid
Show/Hide
|
C21H29NO6
|
1
|
| 1 |
IC50 = 918 nM
|
|
|
|
CP0139207
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C23H24N2O4
|
2
|
| 1 |
IC50 = 950 nM
|
|
|
| 2 |
Ki = 257.04 nM
|
|
|
|
CP0056034
|
11-[(4-methylpiperazin-1-yl)acetyl]-5,11-dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-one
Show/Hide
|
C19H21N5O2
|
1
|
| 1 |
IC50 = 955.6 nM
|
|
|
|
CP0844751
|
3-[(3-methoxy-benzyl)-phenyl-carbamoyloxy]-8,8-dimethyl-8-azonia-bicyclo[3.2.1]octane bromide
Show/Hide
|
C24H31BrN2O3
|
1
|
| 1 |
IC50 = 971.7 nM
|
|
|
|
CP0392206
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid decyl ester
Show/Hide
|
C24H37NO2
|
1
|
| 1 |
IC50 = 983 nM
|
|
|
|
CP0495636
|
(2S)-N-[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]-3-(4-hydroxyphenyl)-2-[[4-(morpholine-4-carbonyl)phenyl]carbamoylamino]propanamide
Show/Hide
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C33H36N6O5
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1
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| 1 |
IC50 = 1000 nM
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CP0506337
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2-chloro-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
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C25H26ClN3O
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1
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| 1 |
IC50 = 1000 nM
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CP0406059
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2-(5-chloro-2-fluorophenyl)-N-(piperidin-4-ylmethyl)benzamide
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C19H20ClFN2O
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1
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| 1 |
IC50 = 1000 nM
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CP0846159
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N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}benzenesulfonamide
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C29H34N2O2S
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1
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| 1 |
IC50 = 1059 nM
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CP0850036
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid heptyl ester oxalic acid
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C23H33NO6
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1
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| 1 |
IC50 = 1095.5 nM
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CP0854412
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 2-bromobenzyl(phenyl)carbamate
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C22H25BrN2O2
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1
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| 1 |
IC50 = 1143.6 nM
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CP0873205
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 4-cyanobenzyl(phenyl)carbamate
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C23H25N3O2
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1
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| 1 |
IC50 = 1161.3 nM
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CP0861083
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-(4-methoxy-phenyl)-ethyl ester oxalic acid
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C25H29NO7
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1
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| 1 |
IC50 = 1218.7 nM
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CP0914385
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 3-phenyl-propyl ester hydrochloride
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C23H28ClNO2
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1
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| 1 |
IC50 = 1244.3 nM
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CP0894397
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(3S)-1-(benzo[d][1,3]dioxol-5-ylmethyl)-3-((S)-3-(3,4-dimethoxyphenyl)-2-(3-(4-(ethoxycarbonyl)phenyl)ureido)propanamido)-1-methylpyrrolidinium
Show/Hide
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C34H41IN4O8
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1
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| 1 |
IC50 = 1258.93 nM
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CP0503060
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N-[[3-[2-methoxy-5-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C27H29N3O4
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1
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| 1 |
IC50 = 1258.93 nM
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CP0517507
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3-phenoxy-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
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C31H31N3O2
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1
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| 1 |
IC50 = 1258.93 nM
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CP0405989
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2-(3-chlorophenyl)-6-fluoro-N-[(4-fluoropiperidin-4-yl)methyl]benzamide
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C19H19ClF2N2O
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1
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| 1 |
IC50 = 1258.93 nM
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CP0471047
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2-(2,5-dichlorophenyl)-6-fluoro-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H19Cl2FN2O
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1
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| 1 |
IC50 = 1258.93 nM
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CP0416360
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2-(3-chlorophenyl)-N-[(3-methylpiperidin-4-yl)methyl]benzamide
Show/Hide
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C20H23ClN2O
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1
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| 1 |
IC50 = 1258.93 nM
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CP0861075
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid hexyl ester oxalic acid
Show/Hide
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C22H31NO6
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1
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| 1 |
IC50 = 1308 nM
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CP0846158
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N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}-N'-(phenylmethyl)urea
Show/Hide
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C31H37N3O
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1
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| 1 |
IC50 = 1338 nM
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CP0383656
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9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid propyl ester
Show/Hide
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C24H26N2O4
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1
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| 1 |
IC50 = 1482.3 nM
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CP0860615
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 2-p-tolyl-ethyl ester oxalic acid
Show/Hide
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C25H29NO6
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1
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| 1 |
IC50 = 1491 nM
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CP0917536
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(endo-8-methyl-8-azabicyclo[3.2.1]octan-3-yl)diphenylmethanol
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C21H25NO
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1
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| 1 |
IC50 = 1498 nM
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CP0417390
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N-benzyl-4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzamide
Show/Hide
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C36H36N6O4
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1
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| 1 |
IC50 = 1584.89 nM
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CP0399234
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N-[[3-[3-[(4-ethylpiperazin-1-yl)methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C28H31N3O3
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1
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| 1 |
IC50 = 1584.89 nM
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CP0468406
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ethyl 4-[[(2S)-3-(4-hydroxyphenyl)-1-[[(3R)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C30H34N4O6
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1
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| 1 |
IC50 = 1584.89 nM
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CP0376534
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1-Methyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine; oxalic acid
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C9H13N3S2
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1
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| 1 |
IC50 = 1600 nM
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CP0381434
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid nonyl ester
Show/Hide
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C23H35NO2
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1
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| 1 |
IC50 = 1600.8 nM
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CP0458944
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8,9-Dimethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C24H26N2O5
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1
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| 1 |
IC50 = 1616.4 nM
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CP0914469
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
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C24H27NO6
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1
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| 1 |
IC50 = 1653.8 nM
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CP0859752
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester oxalic acid
Show/Hide
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C18H23NO6
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1
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| 1 |
IC50 = 1689.3 nM
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CP0849717
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 4-phenyl-butyl ester oxalic acid
Show/Hide
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C26H31NO6
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1
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| 1 |
IC50 = 1842 nM
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CP0862779
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1-Ethyl-5-(3-pentyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-1,2,3,6-tetrahydro-pyridine oxalic acid
Show/Hide
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C22H29N3O5
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1
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| 1 |
IC50 = 1927.8 nM
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CP0875271
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N-Ethyl-N'-{3-[(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}urea
Show/Hide
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C26H35N3O
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1
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| 1 |
IC50 = 1939 nM
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CP0388327
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3-hydroxy-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
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C25H27N3O2
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1
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| 1 |
IC50 = 1995.26 nM
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CP0464268
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3-amino-N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]benzamide
Show/Hide
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C25H28N4O
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1
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| 1 |
IC50 = 1995.26 nM
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CP0400209
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N-[[2-(3-chlorophenyl)phenyl]methyl]piperidine-4-carboxamide
Show/Hide
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C19H21ClN2O
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1
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| 1 |
IC50 = 1995.26 nM
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CP0847170
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 5-phenyl-pentyl ester oxalic acid
Show/Hide
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C27H33NO6
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1
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| 1 |
IC50 = 2046.8 nM
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CP0913099
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 3-methoxybenzyl(phenyl)carbamate
Show/Hide
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C23H28N2O3
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1
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| 1 |
IC50 = 2135.4 nM
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CP0844752
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8-methyl-8-aza-bicyclo[3.2.1]octan-3-yl 3-bromobenzyl(phenyl)carbamate
Show/Hide
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C22H25BrN2O2
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1
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| 1 |
IC50 = 2310.7 nM
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CP0910088
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid propyl ester oxalic acid
Show/Hide
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C19H25NO6
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1
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| 1 |
IC50 = 2312.2 nM
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CP0455902
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4-[[(2S)-1-[[1-[(4-cyanophenyl)methyl]pyrrolidin-3-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]-N-methylbenzamide
Show/Hide
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C30H32N6O4
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1
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| 1 |
IC50 = 2511.89 nM
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CP0464267
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N-[[2-fluoro-3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C26H26FN3O3
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1
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| 1 |
IC50 = 2511.89 nM
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CP0857645
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4-((3'-((benzo[d][1,3]dioxole-5-carboxamido)methyl)biphenyl-3-yl)methyl)-1,1-dimethylpiperazin-1-ium
Show/Hide
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C28H32IN3O3
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1
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| 1 |
IC50 = 2511.89 nM
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CP0506411
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2-(3-chlorophenyl)-6-fluoro-N-[[(3R,4R)-3-methylpiperidin-4-yl]methyl]benzamide
Show/Hide
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C20H22ClFN2O
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1
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| 1 |
IC50 = 2511.89 nM
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CP0393182
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(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid cyclohexyl ester
Show/Hide
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C20H29NO2
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1
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| 1 |
IC50 = 2551.1 nM
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CP0448197
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9-Ethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C24H26N2O4
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1
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| 1 |
IC50 = 2629 nM
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CP0451231
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2,9-Dimethyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O3
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1
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| 1 |
IC50 = 2720.9 nM
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CP0875270
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N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}methanesulfonamide
Show/Hide
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C24H32N2O2S
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1
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| 1 |
IC50 = 2732 nM
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CP0863310
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 3-cyclohexyl-propyl ester oxalic acid
Show/Hide
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C25H35NO6
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1
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| 1 |
IC50 = 2801.3 nM
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CP0404668
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9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid isopropyl ester
Show/Hide
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C24H26N2O4
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1
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| 1 |
IC50 = 2817 nM
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CP0500468
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2,7-Dimethyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C23H24N2O3
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1
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| 1 |
IC50 = 2827.7 nM
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CP0920244
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N-{3-[(3-endo)-8-Methyl-8-azabicyclo[3.2.1]oct-3-yl]-2,2-diphenylpropyl}acetamide
Show/Hide
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C25H32N2O
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1
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| 1 |
IC50 = 2895 nM
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CP0453286
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2-Methyl-9-phenoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C28H26N2O4
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1
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| 1 |
IC50 = 3067.8 nM
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CP0464266
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N-[[2-methyl-5-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C27H29N3O3
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1
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| 1 |
IC50 = 3162.28 nM
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CP0474094
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ethyl 4-[[(2R)-3-(4-hydroxyphenyl)-1-[[(3S)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
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C30H34N4O6
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1
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| 1 |
IC50 = 3162.28 nM
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CP0400210
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2-(3-chlorophenyl)-6-fluoro-N-(1,2,3,6-tetrahydropyridin-4-ylmethyl)benzamide
Show/Hide
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C19H18ClFN2O
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1
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| 1 |
IC50 = 3162.28 nM
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CP0880188
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(3R,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid phenethyl ester oxalic acid
Show/Hide
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C24H29NO6
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1
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| 1 |
IC50 = 3175.4 nM
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CP0408846
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9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid methyl ester
Show/Hide
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C22H22N2O4
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1
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| 1 |
IC50 = 3394 nM
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CP0448414
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9-Methoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C22H22N2O4
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1
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| 1 |
IC50 = 3704.2 nM
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CP0397100
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N-[[3-[3-[(4-acetylpiperazin-1-yl)methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C28H29N3O4
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1
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| 1 |
IC50 = 3981.07 nM
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CP0399238
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N-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-2-(trifluoromethyl)benzamide
Show/Hide
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C26H26F3N3O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0405987
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5-[2-(2,5-dichlorophenyl)-6-fluorophenyl]-3-piperidin-4-yl-1,2,4-oxadiazole
Show/Hide
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C19H16Cl2FN3O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0386486
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2-(3-chlorophenyl)-N-(piperidin-4-ylmethyl)benzamide
Show/Hide
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C19H21ClN2O
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1
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| 1 |
IC50 = 3981.07 nM
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CP0846965
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid phenyl ester oxalic acid
Show/Hide
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C22H23NO6
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1
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| 1 |
IC50 = 4069.7 nM
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CP0860591
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(3S,4R)-1-Ethyl-4-phenyl-piperidine-3-carboxylic acid cyclohexyl ester oxalic acid
Show/Hide
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C22H31NO6
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1
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| 1 |
IC50 = 4514.2 nM
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CP0506335
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N-[[3-[3-(piperazine-1-carbonyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C26H25N3O4
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1
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| 1 |
IC50 = 5011.87 nM
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CP0400212
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2-(3-chlorophenyl)-6-fluoro-N-[[(3S,4R)-4-fluoro-3-methylpiperidin-4-yl]methyl]benzamide
Show/Hide
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C20H21ClF2N2O
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1
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| 1 |
IC50 = 5011.87 nM
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CP0854016
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2,2-diphenyl-ethyl ester oxalic acid
Show/Hide
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C30H31NO6
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1
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| 1 |
IC50 = 5051.5 nM
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CP0510618
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2-Methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
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C22H22N2O3
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1
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| 1 |
IC50 = 5493.9 nM
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CP0860435
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1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid methyl ester oxalic acid
Show/Hide
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C17H21NO6
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1
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| 1 |
IC50 = 5523.7 nM
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CP0474066
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N-[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C25H25N3O3
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1
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| 1 |
IC50 = 6309.57 nM
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CP0506334
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N-[[3-[3-(piperidin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
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C27H28N2O3
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1
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| 1 |
IC50 = 6309.57 nM
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CP0858937
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endo-1-(3-(8-methyl-8-azabicyclo[3.2.1]octan-3-yl)-2,2-diphenylpropyl)urea
Show/Hide
|
C24H31N3O
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1
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| 1 |
IC50 = 6399 nM
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CP0855705
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1-Ethyl-3-(3-pentyl-[1,2,4]oxadiazol-5-yl)-4-phenyl-1,2,3,6-tetrahydro-pyridine oxalic acid
Show/Hide
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C22H29N3O5
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1
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| 1 |
IC50 = 6712.1 nM
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CP0850116
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1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid ethyl ester oxalic acid
Show/Hide
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C18H23NO6
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1
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| 1 |
IC50 = 6874.7 nM
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CP0249049
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3-[4-(2-chlorophenyl)sulfonylpiperazin-1-yl]-6-[(2S)-2-methylpiperidin-1-yl]pyridazine
Show/Hide
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C20H26ClN5O2S
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1
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| 1 |
IC50 = 7000 nM
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CP0532030
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1-(1,3-benzodioxol-5-yl)-3-[[3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]urea
Show/Hide
|
C26H28N4O3
|
1
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| 1 |
IC50 = 7943.28 nM
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CP0850323
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4-[Hydroxy(diphenyl)methyl]-1-[4-(phenyloxy)butyl]-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C30H36BrNO2
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2
|
| 1 |
IC50 = 9500 nM
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| 2 |
Kd = 10 nM
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CP0457513
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8-Methyl-6,7,8,9-tetrahydro-5H-2,4-dithia-1,3,8-triaza-cyclopenta[a]naphthalene
Show/Hide
|
C9H11N3S2
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1
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| 1 |
IC50 = 9700 nM
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CP0399962
|
N-[[3-[3-[(3-oxopiperazin-1-yl)methyl]phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C26H25N3O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0463268
|
N-[[3-[3-(morpholin-4-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C26H26N2O4
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0532029
|
N-[[2-methyl-3-[3-(piperazin-1-ylmethyl)phenyl]phenyl]methyl]-1,3-benzodioxole-5-carboxamide
Show/Hide
|
C27H29N3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0907468
|
1-((3'-((benzo[d][1,3]dioxole-5-carboxamido)methyl)biphenyl-3-yl)methyl)-1-methylpiperazin-1-ium
Show/Hide
|
C27H30IN3O3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0405988
|
2-(3-chlorophenyl)-6-fluoro-N-[[(3S,4R)-3-fluoropiperidin-4-yl]methyl]benzamide
Show/Hide
|
C19H19ClF2N2O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0406800
|
2-(3-chlorophenyl)-N-[[(3R,4S)-3-ethylpiperidin-4-yl]methyl]-6-fluorobenzamide
Show/Hide
|
C21H24ClFN2O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0493270
|
3-chloro-6-(3-chlorophenyl)-2-fluoro-N-[(5-fluoro-1,2,3,6-tetrahydropyridin-4-yl)methyl]benzamide
Show/Hide
|
C19H16Cl2F2N2O
|
1
|
| 1 |
IC50 = 10000 nM
|
|
|
|
CP0795225
|
1-(3-Thiophen-2-yl-phenyl)-ethanone, O-(phenylaminocarbonyl)oxime
Show/Hide
|
C19H16N2O2S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0846156
|
(3-endo)-3-{2-Hydroxy-2,2-bis[2-(methyloxy)phenyl]ethyl}-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
Show/Hide
|
C25H34BrNO3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0919884
|
(3-endo)-3-{2-Hydroxy-2,2-bis[4-(methyloxy)phenyl]ethyl}-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane bromide
Show/Hide
|
C25H34BrNO3
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0447292
|
(9bS)-9b-(4-chloro-3-methylphenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C24H17ClF2N2O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0576561
|
(3R,4S)-1-(2,3-dihydro-1-benzofuran-5-ylsulfonyl)-3-fluoro-4-[(1-methylimidazol-2-yl)sulfanylmethyl]piperidine
Show/Hide
|
C18H22FN3O3S2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0404049
|
8,9-Dimethoxy-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C23H24N2O5
|
1
|
| 1 |
IC50 = 10315.1 nM
|
|
|
|
CP0454447
|
8-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid ethyl ester
Show/Hide
|
C23H24N2O4
|
1
|
| 1 |
IC50 = 10804.1 nM
|
|
|
|
CP0910896
|
4-{Hydroxy[bis(4-methylphenyl)]methyl}-1-{2-[(phenylmethyl)oxy]ethyl}-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C31H38BrNO2
|
1
|
| 1 |
IC50 = 12000 nM
|
|
|
|
CP0448496
|
2-Methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene-1-carboxylic acid methyl ester
Show/Hide
|
C21H20N2O3
|
1
|
| 1 |
IC50 = 12612.2 nM
|
|
|
|
CP0919440
|
4-[Hydroxy(diphenyl)methyl]-1-(2-{[(2-methylphenyl)methyl]oxy}ethyl)-1-azoniabicyclo[2.2.2]octane
Show/Hide
|
C30H36BrNO2
|
2
|
| 1 |
IC50 = 13000 nM
|
|
|
| 2 |
Kd = 3.981 nM
|
|
|
|
CP0853885
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 4-phenyl-butyl ester oxalic acid
Show/Hide
|
C26H31NO6
|
1
|
| 1 |
IC50 = 14309.6 nM
|
|
|
|
CP0403792
|
9-Methoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene
Show/Hide
|
C20H20N2O2
|
1
|
| 1 |
IC50 = 15293.8 nM
|
|
|
|
CP0854472
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid phenyl ester oxalic acid
Show/Hide
|
C22H23NO6
|
1
|
| 1 |
IC50 = 16753.5 nM
|
|
|
|
CP0037621
|
(oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
Show/Hide
|
C12H18N2O
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0910895
|
4-(Hydroxy{bis[3-(methyloxy)phenyl]}methyl)-1-{2-[(phenylmethyl)oxy]ethyl}-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C31H38BrNO4
|
1
|
| 1 |
IC50 = 17000 nM
|
|
|
|
CP0457637
|
ethyl 4-[[(2R)-3-(4-hydroxyphenyl)-1-[[(3R)-1-[(4-hydroxyphenyl)methyl]pyrrolidin-3-yl]amino]-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C30H34N4O6
|
1
|
| 1 |
IC50 = 19952.62 nM
|
|
|
|
CP0904249
|
1-(2-{[(2-Bromophenyl)methyl]oxy}ethyl)-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C29H33Br2NO2
|
2
|
| 1 |
IC50 = 22000 nM
|
|
|
| 2 |
Kd = 3.162 nM
|
|
|
|
CP0880203
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid 3-cyclohexyl-propyl ester oxalic acid
Show/Hide
|
C25H35NO6
|
1
|
| 1 |
IC50 = 24861.7 nM
|
|
|
|
CP0910907
|
4-[Hydroxy(diphenyl)methyl]-1-[2-(methyloxy)ethyl]-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C23H30BrNO2
|
1
|
| 1 |
IC50 = 30000 nM
|
|
|
|
CP0393505
|
N-[3-oxo-3-(4-pyridin-4-ylpiperazin-1-yl)propyl]quinoline-5-sulfonamide
Show/Hide
|
C21H23N5O3S
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0317131
|
(9bS)-9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H15ClF2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0381562
|
9b-(4-chlorophenyl)-1-(3,4-difluorobenzoyl)-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H15ClF2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0381587
|
1-(3,4-difluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H16F2N2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0381598
|
1-(4-fluorobenzoyl)-9b-phenyl-2,3-dihydroimidazo[2,1-a]isoindol-5-one
Show/Hide
|
C23H17FN2O2
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0550227
|
5-[(3-acetylphenoxy)methyl]-N-methyl-N-[(1S)-1-pyridin-2-ylethyl]-1,2-oxazole-3-carboxamide
Show/Hide
|
C21H21N3O4
|
1
|
| 1 |
IC50 > 30000 nM
|
|
|
|
CP0448346
|
8,9-Dimethoxy-2-methyl-11,12-dihydro-3H,6aH,13H-6-oxa-3,12a-diaza-benzo[a]cyclopenta[h]anthracene
Show/Hide
|
C21H22N2O3
|
1
|
| 1 |
IC50 = 32589.6 nM
|
|
|
|
CP0904250
|
4-(Hydroxy{bis[4-(methyloxy)phenyl]}methyl)-1-{2-[(phenylmethyl)oxy]ethyl}-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C31H38BrNO4
|
1
|
| 1 |
IC50 = 36000 nM
|
|
|
|
CP0867807
|
1-[2-({[4-(1,1-Dimethylethyl)phenyl]methyl}oxy)ethyl]-4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C33H42BrNO2
|
1
|
| 1 |
IC50 = 39000 nM
|
|
|
|
CP0861084
|
1-Ethyl-4-phenyl-1,2,5,6-tetrahydro-pyridine-3-carboxylic acid 2-(4-methoxy-phenyl)-ethyl ester oxalic acid
Show/Hide
|
C25H29NO7
|
1
|
| 1 |
IC50 = 52495.5 nM
|
|
|
|
CP0018455
|
1-methyl-3,6-dihydro-2H-pyridine-5-carboxylic acid methyl ester;hydrobromide
Show/Hide
|
C8H13NO2
|
2
|
| 1 |
IC50 = 58000 nM
|
|
|
| 2 |
Ki = 5700 nM
|
|
|
|
CP0915807
|
4-[Hydroxy(diphenyl)methyl]-1-(2-phenylethyl)-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C28H32BrNO
|
1
|
| 1 |
IC50 = 87000 nM
|
|
|
|
CP0847050
|
1-Ethyl-4-phenyl-1,2,3,6-tetrahydro-pyridine-3-carboxylic acid methyl ester oxalic acid
Show/Hide
|
C17H21NO6
|
1
|
| 1 |
IC50 = 88401.3 nM
|
|
|
|
CP0382980
|
6,7,8,9-Tetrahydro-2-thia-1,3,8-triaza-cyclopenta[a]naphthalene
Show/Hide
|
C9H9N3S
|
1
|
| 1 |
IC50 = 100000 nM
|
|
|
|
CP0421075
|
1,4-Dimethyl-5-(4-methylsulfanyl-[1,2,5]thiadiazol-3-yl)-1,2,3,6-tetrahydro-pyridine
Show/Hide
|
C10H15N3S2
|
1
|
| 1 |
IC50 > 100000 nM
|
|
|
|
CP0218742
|
3,4-dihydro-1H-isoquinolin-2-yl-[1-[6-(4-ethylphenoxy)pyrimidin-4-yl]piperidin-4-yl]methanone
Show/Hide
|
C27H30N4O2
|
1
|
| 1 |
IC50 < 1500 nM
|
|
|
|
CP0391916
|
2-[benzyl-[(2S)-3-(4-hydroxyphenyl)-2-[(4-propan-2-yloxycarbonylphenyl)carbamoylamino]propanoyl]amino]ethyl-trimethylazanium
Show/Hide
|
C32H41N4O5+
|
1
|
| 1 |
IC50 > 3300 nM
|
|
|
|
CP0499983
|
propan-2-yl 4-[[(2S)-1-[(1,3-dimethylimidazol-1-ium-2-yl)methyl-methylamino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]carbamoylamino]benzoate
Show/Hide
|
C27H34N5O5+
|
1
|
| 1 |
IC50 > 3300 nM
|
|
|
|
CP0374165
|
2,2-diphenyl-2-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.1]heptan-4-yl]acetonitrile;bromide
Show/Hide
|
C29H31N2O+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.5012 nM
|
|
|
|
CP0374166
|
diphenyl-[1-(4-phenylbutyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol;bromide
Show/Hide
|
C30H36NO+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.5012 nM
|
|
|
|
CP0417321
|
[1-(2-phenoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C28H32NO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.7943 nM
|
|
|
|
CP0417323
|
2,2-diphenyl-2-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]acetonitrile;bromide
Show/Hide
|
C30H33N2O+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 3.162 nM
|
|
|
|
CP0433866
|
[1-[2-[(3-bromophenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C29H33BrNO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.1259 nM
|
|
|
|
CP0474223
|
[1-[2-[(4-chlorophenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C29H33ClNO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.0631 nM
|
|
|
|
CP0474224
|
[1-[2-[(3-methylphenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C30H36NO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.1 nM
|
|
|
|
CP0474225
|
bis(4-fluorophenyl)-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol;bromide
Show/Hide
|
C29H32F2NO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.0631 nM
|
|
|
|
CP0474226
|
[1-[2-[(4-methylphenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C30H36NO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.03981 nM
|
|
|
|
CP0474227
|
[1-[2-[(2-fluorophenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C29H33BrFNO2
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.03981 nM
|
|
|
|
CP0495571
|
4-[2-[4-[hydroxy(diphenyl)methyl]-1-azoniabicyclo[2.2.2]octan-1-yl]ethoxymethyl]benzonitrile;bromide
Show/Hide
|
C30H33N2O2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.3981 nM
|
|
|
|
CP0501932
|
[1-[2-[(3-methoxyphenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C30H36NO3+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 1.995 nM
|
|
|
|
CP0503204
|
[1-[2-[(4-fluorophenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C29H33FNO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.07943 nM
|
|
|
|
CP0515932
|
[1-[2-[(4-bromophenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C29H33BrNO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.03981 nM
|
|
|
|
CP0526132
|
bis(3-fluorophenyl)-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.2]octan-4-yl]methanol;bromide
Show/Hide
|
C29H32F2NO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.2512 nM
|
|
|
|
CP0541214
|
[1-[2-[(3-fluorophenyl)methoxy]ethyl]-1-azoniabicyclo[2.2.2]octan-4-yl]-diphenylmethanol;bromide
Show/Hide
|
C29H33FNO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.02512 nM
|
|
|
|
CP0541215
|
diphenyl-[1-(2-phenylmethoxyethyl)-1-azoniabicyclo[2.2.1]heptan-4-yl]methanol;bromide
Show/Hide
|
C28H32NO2+
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.3981 nM
|
|
|
|
CP0850322
|
4-[Hydroxy(diphenyl)methyl]-1-[3-(phenyloxy)propyl]-1-azoniabicyclo[2.2.2]octane Bromide
Show/Hide
|
C29H34BrNO2
|
2
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Ki = 0.13 nM
|
|
|
|
CP0882700
|
UMECLIDINIUM BROMIDE
Show/Hide
|
C29H34BrNO2
|
3
|
| 1 |
IC50 < 10000 nM
|
|
|
| 2 |
Kd = 0.03162 nM
|
|
|
| 3 |
Ki = 0.06 nM
|
|
|
|
CP0234914
|
N-[[4-fluoro-3-[3-[[(3S)-3-methylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-3-(piperidin-4-ylmethyl)benzamide
Show/Hide
|
C32H39FN4O
|
2
|
| 1 |
Kd = 0.01 nM
|
|
|
| 2 |
Ki = 0.03162 nM
|
|
|
|
CP0666822
|
N-[({5-[(cyclohexyloxy)carbonyl]-2-thienyl}amino)carbonyl]-N-{[2-methyl-7-(2-naphthalenylmethyl)imidazo[2,1-b][1,3]thiazol-7-ium-6-yl]methyl}-L-tyrosinamide
Show/Hide
|
C39H40IN5O5S2
|
1
|
| 1 |
Kd = 0.01259 nM
|
|
|
|
CP0922427
|
(3S)-3-((S)-2-(3-(5-(cyclohexyloxycarbonyl)thiophen-2-yl)ureido)-3-(4-hydroxyphenyl)propanamido)-1-(4-hydroxybenzyl)-1-methylpiperidinium
Show/Hide
|
C34H43IN4O6S
|
1
|
| 1 |
Kd = 0.01995 nM
|
|
|
|
CP0852183
|
(S)-6-((3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)methyl)-2-methyl-7-(naphthalen-2-ylmethyl)-7H-imidazo[2,1-b]thiazol-4-ium 2,2,2-trifluoroacetate
Show/Hide
|
C40H38F3N5O7S
|
1
|
| 1 |
Kd = 0.02512 nM
|
|
|
|
CP0894758
|
(S)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)-3-((4-methylpiperazin-1-yl)methyl)benzamide
Show/Hide
|
C32H40FN5O
|
1
|
| 1 |
Kd = 0.03162 nM
|
|
|
|
CP0918663
|
N-[(6-fluoro-3-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl]-3-propanoyl benzamide
Show/Hide
|
C29H32FN3O2
|
1
|
| 1 |
Kd = 0.05012 nM
|
|
|
|
CP0918664
|
3-acetyl-N-[(6-fluoro-3-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl] benzamide
Show/Hide
|
C28H30FN3O2
|
1
|
| 1 |
Kd = 0.05012 nM
|
|
|
|
CP0894759
|
(S)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)-3-((4-(3-hydroxypropyl)piperazin-1-yl)methyl)benzamide
Show/Hide
|
C34H44FN5O2
|
1
|
| 1 |
Kd = 0.0631 nM
|
|
|
|
CP0844881
|
(S)-1-benzyl-4-(3-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methylcarbamoyl)benzyl)-1-methylpiperazin-1-ium
Show/Hide
|
C39H47FIN5O
|
1
|
| 1 |
Kd = 0.07943 nM
|
|
|
|
CP0907469
|
(S)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)-3-((4-formylpiperazin-1-yl)methyl)benzamide
Show/Hide
|
C32H38FN5O2
|
1
|
| 1 |
Kd = 0.07943 nM
|
|
|
|
CP0891439
|
(3S)-1-allyl-1-(3-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)piperidinium
Show/Hide
|
C35H43IN4O6
|
1
|
| 1 |
Kd = 0.1 nM
|
|
|
|
CP0904302
|
(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(5-(isopropoxycarbonyl)thiophen-2-yl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
|
C31H39IN4O6S
|
1
|
| 1 |
Kd = 0.1 nM
|
|
|
|
CP0941314
|
(S)-4-(3-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methylcarbamoyl)benzyl)-1-methyl-1-propylpiperazin-1-ium
Show/Hide
|
C35H47FIN5O
|
1
|
| 1 |
Kd = 0.1 nM
|
|
|
|
CP0675682
|
N-{(3S)-1-[(3-hydroxyphenyl)methyl]-1-methyl-3-piperidiniumyl}-N-{[(4-{[(1-methylethyl)oxy]carbonyl}phenyl)amino]carbonyl}-L-tyrosinamide
Show/Hide
|
C33H41IN4O6
|
2
|
| 1 |
Kd = 0.1259 nM
|
|
|
| 2 |
Ki = 31.62 nM
|
|
|
|
CP0911423
|
(S)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)-3-(morpholinomethyl)benzamide
Show/Hide
|
C31H37FN4O2
|
1
|
| 1 |
Kd = 0.1259 nM
|
|
|
|
CP0938839
|
3-(3-((6-fluoro-3'-(((S)-3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methylcarbamoyl)benzyl)-3-aza-6-azoniaspiro[5.5]undecane
Show/Hide
|
C36H47FIN5O
|
1
|
| 1 |
Kd = 0.1259 nM
|
|
|
|
CP0386412
|
N-[[4-fluoro-3-[3-[[(3S)-3-methylpiperazin-1-yl]methyl]phenyl]phenyl]methyl]-3-(piperazin-1-ylmethyl)benzamide
Show/Hide
|
C31H38FN5O
|
1
|
| 1 |
Kd = 0.1585 nM
|
|
|
|
CP0938838
|
(S)-4-(3-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methylcarbamoyl)benzyl)-1,1-dimethylpiperazin-1-ium
Show/Hide
|
C33H43FIN5O
|
1
|
| 1 |
Kd = 0.1585 nM
|
|
|
|
CP0858730
|
(S)-3-(((3-(dimethylamino)propyl)(methyl)amino)methyl)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)benzamide
Show/Hide
|
C33H44FN5O
|
1
|
| 1 |
Kd = 0.1995 nM
|
|
|
|
CP0918662
|
3-cyano-N-[(6-fluoro-3-{[(3S)-3-methyl-1-piperazinyl]methyl}-3-biphenylyl)methyl] benzamide
Show/Hide
|
C27H27FN4O
|
1
|
| 1 |
Kd = 0.2512 nM
|
|
|
|
CP0897581
|
(S)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)-3-((4-methyl-1,4-diazepan-1-yl)methyl)benzamide
Show/Hide
|
C33H42FN5O
|
1
|
| 1 |
Kd = 0.2512 nM
|
|
|
|
CP0845449
|
[1-(2-Aminoethyl)-1-azoniabicyclo[2.2.2]oct-4-yl](diphenyl)-methanolate bromide
Show/Hide
|
C22H29BrN2O
|
1
|
| 1 |
Kd = 0.3981 nM
|
|
|
|
CP0869983
|
(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropylcarbamoyl)phenyl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
|
C33H42IN5O5
|
1
|
| 1 |
Kd = 0.631 nM
|
|
|
|
CP0894396
|
(S)-1,1-bis(cyclopropylmethyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)piperidinium
Show/Hide
|
C33H45IN4O5
|
1
|
| 1 |
Kd = 0.631 nM
|
|
|
|
CP0858731
|
(S)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)-3-(piperidin-1-ylmethyl)benzamide
Show/Hide
|
C32H39FN4O
|
1
|
| 1 |
Kd = 0.631 nM
|
|
|
|
CP0858368
|
(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(5-methyl-1,2,4-oxadiazol-3-yl)phenyl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
|
C32H37IN6O5
|
1
|
| 1 |
Kd = 1.995 nM
|
|
|
|
CP0858377
|
(3S)-1-(4-hydroxybenzyl)-3-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(3-methyl-1,2,4-oxadiazol-5-yl)phenyl)ureido)propanamido)-1-methylpiperidinium
Show/Hide
|
C32H37IN6O5
|
1
|
| 1 |
Kd = 1.995 nM
|
|
|
|
CP0880683
|
(S)-2-((S)-3-(4-hydroxyphenyl)-2-(3-(4-(isopropoxycarbonyl)phenyl)ureido)propanamido)-6-azoniaspiro[5.6]dodecane
Show/Hide
|
C31H43IN4O5
|
1
|
| 1 |
Kd = 3.162 nM
|
|
|
|
CP0894760
|
(S)-3-((dimethylamino)methyl)-N-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methyl)benzamide
Show/Hide
|
C29H35FN4O
|
1
|
| 1 |
Kd = 3.162 nM
|
|
|
|
CP0919131
|
(S)-1-(3-((6-fluoro-3'-((3-methylpiperazin-1-yl)methyl)biphenyl-3-yl)methylcarbamoyl)benzyl)-1-methylpiperazin-1-ium
Show/Hide
|
C32H41FIN5O
|
1
|
| 1 |
Kd = 3.162 nM
|
|
|
|
CP0666404
|
Tiotropium bromide
Show/Hide
|
C19H24BrNO5S2
|
3
|
| 1 |
Ki = 0.01 nM
|
|
|
| 2 |
Ki = 0.075 nM
|
|
|
| 3 |
Ki = 0.1995 nM
|
|
|
|
CP0473364
|
N-[3-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]propyl]-2-[3-[2-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(hydroxymethyl)phenyl]ethyl]amino]-2-methylpropyl]phenyl]acetamide
Show/Hide
|
C45H61N3O5
|
1
|
| 1 |
Ki = 0.091 nM
|
|
|
|
CP0090719
|
US8551978, I-60
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0090722
|
US8551978, I-65
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0090723
|
US8551978, I-88
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0090724
|
US8551978, I-89
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0127264
|
US8551978, I-94
Show/Hide
|
C52H58N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0172954
|
US8551978, I-32
Show/Hide
|
C48H50N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0175289
|
US8551978, I-57
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0188924
|
US8551978, I-68
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0188926
|
US8551978, I-84
Show/Hide
|
C51H55FN6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0211764
|
US8551978, I-16
Show/Hide
|
C46H54N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0223279
|
US8551978, I-2
Show/Hide
|
C45H52N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0223281
|
US8551978, I-7
Show/Hide
|
C45H52N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0224162
|
US8551978, I-96
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0226204
|
US8551978, I-81
Show/Hide
|
C52H58N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0227538
|
US8551978, I-79
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0250247
|
US8551978, I-3
Show/Hide
|
C45H52N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0250252
|
US8551978, I-77
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0293285
|
US8551978, I-5
Show/Hide
|
C46H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0293286
|
US8551978, I-10
Show/Hide
|
C46H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0315619
|
US8551978, I-6
Show/Hide
|
C45H51ClN6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0315620
|
US8551978, I-24
Show/Hide
|
C48H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0315621
|
US8551978, I-82
Show/Hide
|
C52H58N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0321872
|
US8551978, I-19
Show/Hide
|
C46H53ClN6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0321873
|
US8551978, I-23
Show/Hide
|
C48H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0321875
|
US8551978, I-59
Show/Hide
|
C48H50N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0383578
|
US8551978, I-87
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0384079
|
US8551978, I-71
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0384093
|
US8551978, I-90
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0387713
|
US8551978, I-12
Show/Hide
|
C47H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0390186
|
US8816088, 13
Show/Hide
|
C46H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0393354
|
US8551978, I-49
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0394815
|
US8551978, I-11
Show/Hide
|
C47H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0410636
|
US8816088, 18
Show/Hide
|
C47H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0418272
|
US8551978, I-27
Show/Hide
|
C48H50N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0418392
|
US8551978, I-46
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0443098
|
US8816088, 7
Show/Hide
|
C44H50N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0479070
|
US8551978, I-25
Show/Hide
|
C47H48N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0480766
|
US8551978, I-40
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0480783
|
US8551978, I-63
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0484460
|
US8551978, I-53
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0491886
|
US8551978, I-61
Show/Hide
|
C49H51ClN6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0516802
|
US8551978, I-21
Show/Hide
|
C46H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0529358
|
US8551978, I-17
Show/Hide
|
C46H54N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0539113
|
US8551978, I-43
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0539114
|
US8551978, 266
Show/Hide
|
C45H52N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0540722
|
US8551978, I-69
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0542047
|
US8551978, I-44
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0549630
|
US8551978, I-20
Show/Hide
|
C46H54N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0551307
|
US8551978, I-22
Show/Hide
|
C48H58N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0551356
|
US8551978, I-62
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0553835
|
US8551978, I-9
Show/Hide
|
C46H54N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0553836
|
US8551978, I-29
Show/Hide
|
C48H50N6O8
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0569070
|
US8551978, I-1
Show/Hide
|
C44H50N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0910692
|
US8551978, I-34::US8816088, I-34
Show/Hide
|
C48H50N6O7
|
1
|
| 1 |
Ki = 0.1 nM
|
|
|
|
CP0461986
|
5-methyl-5-(3-phenoxyazetidin-1-yl)-2,2-diphenylhexanamide
Show/Hide
|
C28H32N2O2
|
1
|
| 1 |
Ki = 0.11 nM
|
|
|
|
CP0036569
|
(R)-3-(3-methoxyquinuclidin-3-yl)-1,1-diphenylprop-2-yn-1-ol
Show/Hide
|
C23H25NO2
|
1
|
| 1 |
Ki = 0.1259 nM
|
|
|
|
CP0199765
|
5-[3-(3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
Show/Hide
|
C28H32N2O3
|
1
|
| 1 |
Ki = 0.128 nM
|
|
|
|
CP0387963
|
5-[3-(2-fluoro-3-hydroxyphenoxy)azetidin-1-yl]-5-methyl-2,2-diphenylhexanamide
Show/Hide
|
C28H31FN2O3
|
1
|
| 1 |
Ki = 0.163 nM
|
|
|
|
CP0394158
|
(2R)-N-(1-cyclopropylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1 -[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C41H47F3N4O4
|
1
|
| 1 |
Ki = 0.17 nM
|
|
|
|
CP0392008
|
5-[(3S)-3-(3-hydroxyphenoxy)pyrrolidin-1-yl]-5-methyl-2,2-diphenylhexanamide
Show/Hide
|
C29H34N2O3
|
1
|
| 1 |
Ki = 0.18 nM
|
|
|
|
CP0467303
|
(2R)-N-(1-cyclopentylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C43H51F3N4O4
|
1
|
| 1 |
Ki = 0.19 nM
|
|
|
|
CP0862072
|
(R)-1-cyclohexyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenylprop-2-yn-1-ol
Show/Hide
|
C23H31NO2
|
1
|
| 1 |
Ki = 0.1995 nM
|
|
|
|
CP0090718
|
US8551978, I-54
Show/Hide
|
C51H56N6O8
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0172957
|
US8551978, I-51
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0175286
|
US8551978, I-39
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0175287
|
US8551978, I-52
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0175290
|
US8551978, I-86
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0211715
|
BDBM41533
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0227528
|
US8551978, I-37
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0231278
|
US8551978, I-92
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0231309
|
US8551978, I-45
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0250248
|
US8551978, I-28
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0250249
|
US8551978, I-36
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0250250
|
US8551978, I-55
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0250251
|
US8551978, I-73
Show/Hide
|
C51H55FN6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0293287
|
US8551978, I-33
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0293288
|
US8551978, I-38
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0325962
|
US8551978, I-26
Show/Hide
|
C48H50N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0384061
|
US8551978, I-85
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0418391
|
US8551978, I-47
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0442142
|
US8551978, I-56
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0443669
|
US8551978, I-58
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0451573
|
US8551978, I-80
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0457084
|
US8551978, I-95
Show/Hide
|
C51H55FN6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0484461
|
US8551978, I-42
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0490783
|
US8551978, I-30
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0531315
|
US8551978, I-75
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0536252
|
US8551978, I-31
Show/Hide
|
C48H49ClN6O8
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0550490
|
US8551978, I-83
Show/Hide
|
C52H58N6O8
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0550491
|
US8551978, I-91
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.2 nM
|
|
|
|
CP0387964
|
5-[(3R)-3-(3-hydroxyphenoxy)pyrrolidin-1-yl]-5-methyl-2,2-diphenylhexanamide
Show/Hide
|
C29H34N2O3
|
1
|
| 1 |
Ki = 0.201 nM
|
|
|
|
CP0070586
|
Ipratropium Bromide
Show/Hide
|
C20H30BrNO3
|
3
|
| 1 |
Ki = 0.213 nM
|
|
|
| 2 |
Ki = 0.29 nM
|
|
|
| 3 |
Ki = 0.3162 nM
|
|
|
|
CP0849054
|
1-[1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carbonyl]-pyrrolidine-2-carboxylic acid (1-cyclohexylmethyl-piperidin-3-ylmethyl)-amide
Show/Hide
|
C44H56N4O3
|
1
|
| 1 |
Ki = 0.25 nM
|
|
|
|
CP0452021
|
N-[3-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]propyl]-2-[3-[2-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(methanesulfonamido)phenyl]ethyl]amino]-2-methylpropyl]phenyl]acetamide
Show/Hide
|
C45H62N4O6S
|
1
|
| 1 |
Ki = 0.276 nM
|
|
|
|
CP0127263
|
US8551978, I-74
Show/Hide
|
C49H52N6O7
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0211696
|
US8551978, I-76
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0211766
|
US8551978, I-48
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0226203
|
US8551978, I-78
Show/Hide
|
C51H56N6O7
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0443670
|
US8551978, I-70
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0539111
|
US8551978, I-41
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0551906
|
US8551978, I-64
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.3 nM
|
|
|
|
CP0224386
|
5-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-hydroxyphenyl)butoxy)phenethylamino)-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one
Show/Hide
|
C44H55N3O5
|
1
|
| 1 |
Ki = 0.305 nM
|
|
|
|
CP0847176
|
N-({2-[(1-Cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-methyl)-3,3,3-triphenyl-propionamide
Show/Hide
|
C39H50N4O3
|
1
|
| 1 |
Ki = 0.31 nM
|
|
|
|
CP0862069
|
(R)-1-cyclooctyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenylprop-2-yn-1-ol
Show/Hide
|
C25H35NO2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0950508
|
(R)-1-cycloheptyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenylprop-2-yn-1-ol
Show/Hide
|
C24H33NO2
|
1
|
| 1 |
Ki = 0.3162 nM
|
|
|
|
CP0889526
|
(S)-2-((2R,5S)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
|
C21H32INOS
|
1
|
| 1 |
Ki = 0.3388 nM
|
|
|
|
CP0376043
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H41Cl3N4O4
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0376654
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-[(3R)-3-piperidinylmethyl]-pyrrolidine-2-carboxamide
Show/Hide
|
C37H41F3N4O4
|
1
|
| 1 |
Ki = 0.39 nM
|
|
|
|
CP0460724
|
2-(3-((R)-2-((R)-2-(3,5-dihydroxyphenyl)-2-hydroxyethylamino)propyl)phenyl)-N-(3-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-hydroxyphenyl)propyl)acetamide
Show/Hide
|
C43H57N3O5
|
1
|
| 1 |
Ki = 0.397 nM
|
|
|
|
CP0227532
|
US8551978, I-50
Show/Hide
|
C50H54N6O7
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0529360
|
US8551978, I-72
Show/Hide
|
C52H58N6O8
|
1
|
| 1 |
Ki = 0.4 nM
|
|
|
|
CP0849742
|
1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carboxylic acid {2-[(1-cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethyl}-amide
Show/Hide
|
C42H54N4O3
|
1
|
| 1 |
Ki = 0.47 nM
|
|
|
|
CP0458127
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43F3N4O4
|
1
|
| 1 |
Ki = 0.48 nM
|
|
|
|
CP0109931
|
ATROPEN
Show/Hide
|
C17H23NO3
|
2
|
| 1 |
Ki = 0.5 nM
|
|
|
| 2 |
Ki = 0.53 nM
|
|
|
|
CP0393859
|
(2R)-N-(1-cyclopentyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)-propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C42H49F3N4O4
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0408072
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine -2-yl)-carbonyl-N-(1-methyl-4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43F3N4O4
|
1
|
| 1 |
Ki = 0.51 nM
|
|
|
|
CP0390495
|
(2R)-N-(1-cyclobutylmethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C42H49F3N4O4
|
1
|
| 1 |
Ki = 0.53 nM
|
|
|
|
CP0877788
|
(S)-2-((2S,5S)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
|
C21H32INOS
|
1
|
| 1 |
Ki = 0.5888 nM
|
|
|
|
CP0473363
|
N-[5-[(1R)-2-[2-[4-[4-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]butoxy]phenyl]ethylamino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
Show/Hide
|
C42H57N3O6S
|
1
|
| 1 |
Ki = 0.634 nM
|
|
|
|
CP0869209
|
(S)-2-((S)-2,2-diphenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
|
C21H26INOS
|
1
|
| 1 |
Ki = 0.7413 nM
|
|
|
|
CP0886180
|
N-(2-{2-[(1-Cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-ethylcarbamoyl}-ethyl)-3,3,3-triphenyl-propionamide
Show/Hide
|
C40H52N4O3
|
1
|
| 1 |
Ki = 0.76 nM
|
|
|
|
CP0473365
|
2-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-(4-(4-(2-((R)-2-hydroxy-2-(4-hydroxy-3-(hydroxymethyl)phenyl)ethylamino)ethyl)phenoxy)butyl)phenol
Show/Hide
|
C42H56N2O5
|
1
|
| 1 |
Ki = 0.765 nM
|
|
|
|
CP0378654
|
1-[3-[4-[7-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]heptyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C32H47N5O2S
|
1
|
| 1 |
Ki = 0.7943 nM
|
|
|
|
CP0315444
|
US8551978, I-93
Show/Hide
|
C52H58N6O7
|
1
|
| 1 |
Ki = 0.8 nM
|
|
|
|
CP0010653
|
2-{1-[2-(2,3-Dihydro-benzofuran-5-yl)-ethyl]-pyrrolidin-3-yl}-2,2-diphenyl-acetamide (Darifenacin)
Show/Hide
|
C28H30N2O2
|
1
|
| 1 |
Ki = 0.84 nM
|
|
|
|
CP0858803
|
(2S,2'R,5'S)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H29NOS
|
1
|
| 1 |
Ki = 0.8913 nM
|
|
|
|
CP0881062
|
(R)-2-((2R,5R)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
|
C21H32INOS
|
1
|
| 1 |
Ki = 0.912 nM
|
|
|
|
CP0390498
|
(2R)-N-(1-ethyl-4-piperidinylmethyl)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonylpyrrolidine-2-carboxamide
Show/Hide
|
C39H45F3N4O4
|
1
|
| 1 |
Ki = 0.92 nM
|
|
|
|
CP0425016
|
3-(1-benzyl-azepin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C28H31N3O
|
1
|
| 1 |
Ki = 0.96 nM
|
|
|
|
CP0378245
|
N-[5-[(1R)-2-[6-[4-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]butoxy]hexylamino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
Show/Hide
|
C40H61N3O6S
|
1
|
| 1 |
Ki = 0.99 nM
|
|
|
|
CP0859758
|
6-(3,3,3-Triphenyl-propionylamino)-hexanoic acid (1-cyclohexylmethyl-piperidin-3-ylmethyl)-amide
Show/Hide
|
C40H53N3O2
|
1
|
| 1 |
Ki = 1 nM
|
|
|
|
CP0378646
|
1-[3-[4-[9-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]nonyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C34H51N5O2S
|
1
|
| 1 |
Ki = 1.096 nM
|
|
|
|
CP0379405
|
(R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-cyclopentyl-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C20H30N2O2
|
1
|
| 1 |
Ki = 1.1 nM
|
|
|
|
CP0498259
|
(R)-1-[4-(2-Amino-ethylidene)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C20H26F2N2O2
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0390496
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H43Cl3N4O4
|
1
|
| 1 |
Ki = 1.2 nM
|
|
|
|
CP0462909
|
1-(2-cyclopropyl-5-methyl-6-(pyrrolidin-1-yl)pyrimidin-4-yl)azepane
Show/Hide
|
C18H28N4
|
1
|
| 1 |
Ki = 1.3 nM
|
|
|
|
CP0409482
|
(R)-1-(4-Amino-piperidin-1-yl)-2-cyclopentyl-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C18H26N2O2
|
1
|
| 1 |
Ki = 1.4 nM
|
|
|
|
CP0881063
|
(2R,2'R,5'R)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H29NOS
|
1
|
| 1 |
Ki = 1.445 nM
|
|
|
|
CP0373204
|
N-[3-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]propyl]-11-[[(2R)-2-hydroxy-2-[4-hydroxy-3-(methanesulfonamido)phenyl]ethyl]amino]undecanamide
Show/Hide
|
C44H68N4O6S
|
1
|
| 1 |
Ki = 1.45 nM
|
|
|
|
CP0858907
|
(S)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C20H26INO2
|
1
|
| 1 |
Ki = 1.479 nM
|
|
|
|
CP0894757
|
(R)-2-(5-((R)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 1.514 nM
|
|
|
|
CP0062485
|
4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
Show/Hide
|
C22H31NO3
|
1
|
| 1 |
Ki = 1.514 nM
|
|
|
|
CP0879684
|
(S)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
|
C21H25NO6
|
1
|
| 1 |
Ki = 1.514 nM
|
|
|
|
CP0431973
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-chlorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-((3R)-3-piperidinylmethyl)-pyrrolidine-2-carboxamide
Show/Hide
|
C37H41Cl3N4O4
|
1
|
| 1 |
Ki = 1.6 nM
|
|
|
|
CP0439251
|
(R)-cyclohexyl-[5-[(2R)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
|
C22H29NO2
|
1
|
| 1 |
Ki = 1.66 nM
|
|
|
|
CP0877786
|
(2S,2'S,5'S)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H29NOS
|
1
|
| 1 |
Ki = 1.698 nM
|
|
|
|
CP0404348
|
(R)-1-(4-Aminomethyl-piperidin-1-yl)-2-cyclopentyl-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C19H28N2O2
|
1
|
| 1 |
Ki = 1.7 nM
|
|
|
|
CP0505424
|
3-(1-(3-methylbenzyl)-piperidin-4-yl)-5,5-di-(2-thienyl)-imidazolidin-2-one
Show/Hide
|
C24H27N3OS2
|
1
|
| 1 |
Ki = 1.72 nM
|
|
|
|
CP0871074
|
(2R,5R)-2-cyclohexyl-2-phenyl-5-((dimethylamino)methyl)-1,3-oxathiolane methiodide
Show/Hide
|
C19H30INOS
|
1
|
| 1 |
Ki = 1.778 nM
|
|
|
|
CP0387917
|
5-methyl-5-[(3S)-3-phenoxypyrrolidin-1-yl]-2,2-diphenylhexanamide
Show/Hide
|
C29H34N2O2
|
1
|
| 1 |
Ki = 1.8 nM
|
|
|
|
CP0428351
|
3-(1-benzylpiperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C27H29N3O
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0392021
|
5-[(3S)-3-phenoxypyrrolidin-1-yl]-2,2-diphenylpentanamide
Show/Hide
|
C27H30N2O2
|
1
|
| 1 |
Ki = 1.9 nM
|
|
|
|
CP0845114
|
(S)-1-cycloheptyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenylprop-2-yn-1-ol
Show/Hide
|
C24H33NO2
|
1
|
| 1 |
Ki = 1.995 nM
|
|
|
|
CP0480832
|
2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C26H32F2N2O2
|
1
|
| 1 |
Ki = 2 nM
|
|
|
|
CP0377612
|
N-[3-[[1-(cyclohexylmethyl)piperidin-3-yl]methylamino]-3-oxopropyl]-4-(3,3,3-triphenylpropanoylamino)butanamide
Show/Hide
|
C41H54N4O3
|
1
|
| 1 |
Ki = 2.1 nM
|
|
|
|
CP0858802
|
(2R,2'S,5'R)-1-methyl-2-(2-cyclohexyl-2-phenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H29NOS
|
1
|
| 1 |
Ki = 2.188 nM
|
|
|
|
CP0858902
|
(+/-)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
|
C21H25NO6
|
1
|
| 1 |
Ki = 2.188 nM
|
|
|
|
CP0860436
|
1-(3,3,3-Triphenyl-propionyl)-pyrrolidine-2-carboxylic acid {[(1-cyclohexylmethyl-piperidin-3-ylmethyl)-carbamoyl]-methyl}-amide
Show/Hide
|
C41H52N4O3
|
1
|
| 1 |
Ki = 2.2 nM
|
|
|
|
CP0374993
|
2-Cyclopentyl-2-hydroxy-N-[1-(3-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C26H34N2O2
|
1
|
| 1 |
Ki = 2.3 nM
|
|
|
|
CP0532138
|
3-(1-(3-methylbenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C28H31N3O
|
1
|
| 1 |
Ki = 2.37 nM
|
|
|
|
CP0485213
|
(2R)-1-((2S,4R)-4-hydroxy-1-[3,3,3-tris(4-fluorophenyl)propanoyl]pyrrolidine-2-yl)carbonyl-N-[1-(2-propyl)-4-piperidinylmethyl]pyrrolidine-2-carboxamide
Show/Hide
|
C34H36F3N3O4
|
1
|
| 1 |
Ki = 2.4 nM
|
|
|
|
CP0877787
|
(2R,5'R)-1-methyl2-(2,2-diphenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H23NOS
|
1
|
| 1 |
Ki = 2.455 nM
|
|
|
|
CP0379015
|
N-(1-benzylpiperidin-4-yl)-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
|
C25H32N2O2
|
1
|
| 1 |
Ki = 2.5 nM
|
|
|
|
CP0862068
|
(S)-1-cyclooctyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenylprop-2-yn-1-ol
Show/Hide
|
C25H35NO2
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0877619
|
4-(3-methoxyquinuclidin-3-yl)-2,2-diphenylbut-3-ynenitrile
Show/Hide
|
C24H24N2O
|
1
|
| 1 |
Ki = 2.512 nM
|
|
|
|
CP0532141
|
3-(1-benzyl-piperidin-4-yl)-5-phenyl-5-cyclohexyl-imidazolidin-2-one
Show/Hide
|
C27H35N3O
|
1
|
| 1 |
Ki = 2.57 nM
|
|
|
|
CP0440619
|
1-azabicyclo[2.2.2]octan-3-yl N-[2-(4-fluorophenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C22H25FN2O2
|
1
|
| 1 |
Ki = 2.6 nM
|
|
|
|
CP0425019
|
3-(1-benzyl-piperidin-4-yl)-5,5-di-(2-thienyl)-imidazolidin-2-one
Show/Hide
|
C23H25N3OS2
|
1
|
| 1 |
Ki = 2.7 nM
|
|
|
|
CP0446373
|
3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(2-thienyl)-imidazolidin-2-one
Show/Hide
|
C23H24FN3OS2
|
1
|
| 1 |
Ki = 2.75 nM
|
|
|
|
CP0376761
|
(R)-N-[1-(6-Amino-pyridin-2-ylmethyl)-piperidin-4-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C24H30F2N4O2
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0373475
|
3-(1-benzyl-piperidin-4-yl)-5,5-di-(4-fluorophenyl)-imidazolidin-2-one
Show/Hide
|
C27H27F2N3O
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0390497
|
(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-(4-piperidinylethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C38H46N4O4
|
1
|
| 1 |
Ki = 2.8 nM
|
|
|
|
CP0399528
|
1,9-di[4-(1-methyl-1,2,3,6-tetrahydro-5-pyridinyl)-1,2,5-thiadiazol-3-yloxy]nonane
Show/Hide
|
C25H38N6O2S2
|
1
|
| 1 |
Ki = 2.884 nM
|
|
|
|
CP0373693
|
(R)-1-(3-Aminomethyl-pyrrolidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C18H24F2N2O2
|
1
|
| 1 |
Ki = 2.9 nM
|
|
|
|
CP0381014
|
2-(3,3-Difluoro-cyclopentyl)-N-[1-(3-fluoro-benzyl)-piperidin-4-yl]-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C25H29F3N2O2
|
1
|
| 1 |
Ki = 3.1 nM
|
|
|
|
CP0428328
|
3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C27H28ClN3O
|
1
|
| 1 |
Ki = 3.15 nM
|
|
|
|
CP0384377
|
2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-(1-thiophen-3-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
|
C23H28F2N2O2S
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0159311
|
6-(azepan-1-yl)-N,2-dicyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C17H26N4
|
1
|
| 1 |
Ki = 3.2 nM
|
|
|
|
CP0404810
|
N-[[1-(cyclohexylmethyl)piperidin-3-yl]methyl]-4-[[2-(3,3,3-triphenylpropanoylamino)acetyl]amino]butanamide
Show/Hide
|
C40H52N4O3
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0476046
|
(R)-1-[4-(2-Amino-ethyl)-4-methyl-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C21H30F2N2O2
|
1
|
| 1 |
Ki = 3.3 nM
|
|
|
|
CP0379378
|
2-Cyclopentyl-2-hydroxy-N-[1-(5-methyl-thiophen-3-ylmethyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C24H32N2O2S
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0431655
|
2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-methoxy-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C26H32F2N2O3
|
1
|
| 1 |
Ki = 3.5 nM
|
|
|
|
CP0465017
|
2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-thiophen-3-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
|
C23H30N2O2S
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0007317
|
(+)-(R)-2-(alpha-(2-(Diisopropylamino)ethyl)benzyl)-p-cresol
Show/Hide
|
C22H31NO
|
1
|
| 1 |
Ki = 3.6 nM
|
|
|
|
CP0867620
|
(+/-)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C20H26INO2
|
1
|
| 1 |
Ki = 3.631 nM
|
|
|
|
CP0448156
|
(R)-1-[4-(2-Amino-ethyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C20H28F2N2O2
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0393862
|
(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-((3R)-3-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H44N4O4
|
1
|
| 1 |
Ki = 3.7 nM
|
|
|
|
CP0461302
|
(2R)-N-(1-benzylpiperidin-4-yl)-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
|
C25H30F2N2O2
|
1
|
| 1 |
Ki = 3.8 nM
|
|
|
|
CP0440300
|
5-methyl-5-(4-phenoxypiperidin-1-yl)-2,2-diphenylhexanamide
Show/Hide
|
C30H36N2O2
|
1
|
| 1 |
Ki = 3.9 nM
|
|
|
|
CP0172665
|
(S)-1-cyclohexyl-3-((R)-3-methoxyquinuclidin-3-yl)-1-phenylprop-2-yn-1-ol
Show/Hide
|
C23H31NO2
|
1
|
| 1 |
Ki = 3.981 nM
|
|
|
|
CP0505686
|
3-(1-benzyl-tropin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C29H31N3O
|
1
|
| 1 |
Ki = 4.1 nM
|
|
|
|
CP0178512
|
(R)-2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C24H36N2O2
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0390494
|
(2R)-1-[(2S,4R)-4-hydroxy-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-yl]carbonyl-N-(4-piperidinylmethyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H44N4O4
|
1
|
| 1 |
Ki = 4.2 nM
|
|
|
|
CP0446348
|
3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C27H28FN3O
|
1
|
| 1 |
Ki = 4.32 nM
|
|
|
|
CP0505425
|
3-(1-(3-methylbenzyl)-piperidin-4-yl)-5-phenyl-5-cyclohexyl-imidazolidin-2-one
Show/Hide
|
C28H37N3O
|
1
|
| 1 |
Ki = 4.54 nM
|
|
|
|
CP0378653
|
1-[3-[4-[5-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]pentyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C30H43N5O2S
|
1
|
| 1 |
Ki = 4.677 nM
|
|
|
|
CP0460723
|
4-((R)-2-(4-(4-(3-((R)-3-(diisopropylamino)-1-phenylpropyl)-4-hydroxyphenyl)butoxy)phenethylamino)-1-hydroxyethyl)benzene-1,2-diol
Show/Hide
|
C41H54N2O5
|
1
|
| 1 |
Ki = 4.7 nM
|
|
|
|
CP0436000
|
3-(1-(3-fluorobenzyl)-piperidin-4-yl)-5,5-di-(4-fluorophenyl)-imidazolidin-2-one
Show/Hide
|
C27H26F3N3O
|
1
|
| 1 |
Ki = 4.83 nM
|
|
|
|
CP0881061
|
(R)-2-((2S,5R)-2-cyclohexyl-2-phenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
|
C21H32INOS
|
1
|
| 1 |
Ki = 4.898 nM
|
|
|
|
CP0869207
|
(R)-2-((R)-2,2-diphenyl-[1,3]oxathiolan-5-yl)-1,1-dimethyl-pyrrolidinium iodide
Show/Hide
|
C21H26INOS
|
1
|
| 1 |
Ki = 5.012 nM
|
|
|
|
CP0373659
|
(R)-1-(4-Amino-piperidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C18H24F2N2O2
|
1
|
| 1 |
Ki = 5.1 nM
|
|
|
|
CP0876058
|
(2S,5'S)-1-methyl 2-(2,2-diphenyl-1,3-oxathiolan-5-yl)pirrolidine
Show/Hide
|
C20H23NOS
|
1
|
| 1 |
Ki = 5.248 nM
|
|
|
|
CP0448091
|
2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hydroxy-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C25H30F2N2O3
|
1
|
| 1 |
Ki = 5.4 nM
|
|
|
|
CP0380577
|
2-Cyclopentyl-2-hydroxy-N-[1-(3-methoxy-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C26H34N2O3
|
1
|
| 1 |
Ki = 5.9 nM
|
|
|
|
CP0393596
|
(2R)-N-[1-[(4-amino-3-fluorophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
|
C25H30F3N3O2
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0452020
|
N-[5-[(1R)-2-[2-[3-[(1R)-3-[di(propan-2-yl)amino]-1-phenylpropyl]-4-hydroxyphenyl]ethylamino]-1-hydroxyethyl]-2-hydroxyphenyl]methanesulfonamide
Show/Hide
|
C32H45N3O5S
|
1
|
| 1 |
Ki = 6.1 nM
|
|
|
|
CP0380673
|
2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C24H34F2N2O2
|
1
|
| 1 |
Ki = 6.2 nM
|
|
|
|
CP0483575
|
6-(3-aza-bicyclo[3.2.1]octan-3-yl)-N,2-dicyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C18H26N4
|
1
|
| 1 |
Ki = 6.3 nM
|
|
|
|
CP0378043
|
2-Cyclopentyl-2-hydroxy-N-[1-(4-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C26H34N2O2
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0392023
|
5-methyl-5-[(3R)-3-phenoxypyrrolidin-1-yl]-2,2-diphenylhexanamide
Show/Hide
|
C29H34N2O2
|
1
|
| 1 |
Ki = 6.4 nM
|
|
|
|
CP0446374
|
3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5-phenyl-5-cyclohexyl-imidazolidin-2-one
Show/Hide
|
C27H34ClN3O
|
1
|
| 1 |
Ki = 6.59 nM
|
|
|
|
CP0425033
|
3-(1-(3-chlorobenzyl)-piperidin-4-yl)-5,5-di-(4-fluorophenyl)-imidazolidin-2-one
Show/Hide
|
C27H26ClF2N3O
|
1
|
| 1 |
Ki = 6.7 nM
|
|
|
|
CP0379399
|
(2R)-N-[1-[(3-aminophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
|
C25H31F2N3O2
|
1
|
| 1 |
Ki = 6.9 nM
|
|
|
|
CP0409513
|
(R)-1-[4-(2-Amino-ethyl)-4-ethyl-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C22H32F2N2O2
|
1
|
| 1 |
Ki = 7 nM
|
|
|
|
CP0874916
|
2-(5-(cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 7.244 nM
|
|
|
|
CP0532143
|
3-(1-(3-hydroxybenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C27H29N3O2
|
1
|
| 1 |
Ki = 7.6 nM
|
|
|
|
CP0405687
|
cyclohexyl-[5-(1-methylpyrrolidin-2-yl)furan-2-yl]-phenylmethanol
Show/Hide
|
C22H29NO2
|
1
|
| 1 |
Ki = 7.762 nM
|
|
|
|
CP0371787
|
5-(4-Hexyloxy-[1,2,5]thiadiazol-3-yl)-1-methyl-1,2,3,6-tetrahydro-pyridine; oxalic acid
Show/Hide
|
C14H23N3OS
|
1
|
| 1 |
Ki = 7.762 nM
|
|
|
|
CP0515291
|
(2R)-N-[1-[(4-aminophenyl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
|
C25H31F2N3O2
|
1
|
| 1 |
Ki = 7.8 nM
|
|
|
|
CP0451719
|
3-(1-(3-aminobenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C27H30N4O
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0435433
|
6-(azepan-1-yl)-N-cyclobutyl-2-cyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C18H28N4
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0518025
|
(+,-)-6-(azepan-1-yl)-2-cyclopropyl-5-methyl-N-(2-methylcyclopropyl)pyrimidin-4-amine
Show/Hide
|
C18H28N4
|
1
|
| 1 |
Ki = 7.9 nM
|
|
|
|
CP0413084
|
1-azabicyclo[2.2.2]octan-3-yl N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
Ki = 8 nM
|
|
|
|
CP0404392
|
(R)-1-(4-Amino-4-methyl-piperidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C19H26F2N2O2
|
1
|
| 1 |
Ki = 8.3 nM
|
|
|
|
CP0532139
|
3-(1-(3-methoxybenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C28H31N3O2
|
1
|
| 1 |
Ki = 8.8 nM
|
|
|
|
CP0493913
|
2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(6-methyl-pyridin-2-ylmethyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C25H31F2N3O2
|
1
|
| 1 |
Ki = 8.9 nM
|
|
|
|
CP0858486
|
2-(5-(cyclohexyl(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO
|
1
|
| 1 |
Ki = 8.913 nM
|
|
|
|
CP0880938
|
(S)-2-(5-((R)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 9.333 nM
|
|
|
|
CP0426808
|
(R)-1-[4-(2-Amino-ethyl)-piperazin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C19H27F2N3O2
|
1
|
| 1 |
Ki = 9.6 nM
|
|
|
|
CP0855359
|
(R)-3-methoxy-3-(3-methoxy-3,3-diphenylprop-1-ynyl)quinuclidine
Show/Hide
|
C24H27NO2
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0442368
|
4-(azepan-1-yl)-2-cyclopropyl-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b]azepine
Show/Hide
|
C17H26N4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0442369
|
6-(azepan-1-yl)-2-cyclopropyl-5-methyl-N-(1-methylcyclopropyl)pyrimidin-4-amine
Show/Hide
|
C18H28N4
|
1
|
| 1 |
Ki = 10 nM
|
|
|
|
CP0415932
|
1-[3-[4-[11-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]undecyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C36H55N5O2S
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1
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| 1 |
Ki = 10 nM
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CP0464724
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2-(3-Fluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C24H35FN2O2
|
1
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| 1 |
Ki = 11 nM
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CP0503519
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2-Cyclopentyl-2-hydroxy-N-[1-(6-methyl-pyridin-2-ylmethyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C25H33N3O2
|
1
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| 1 |
Ki = 11 nM
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CP0480584
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(R)-1-(4-Aminomethyl-piperidin-1-yl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C19H26F2N2O2
|
1
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| 1 |
Ki = 11 nM
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CP0405956
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N-[1-(cycloheptylmethyl)piperidin-4-yl]-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
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C26H40N2O2
|
1
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| 1 |
Ki = 12 nM
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CP0380674
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-(1-pyridin-2-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
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C24H29F2N3O2
|
1
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| 1 |
Ki = 13 nM
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CP0431861
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N,2-dicyclopropyl-5-methyl-6-piperidin-1-ylpyrimidin-4-amine
Show/Hide
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C16H24N4
|
1
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| 1 |
Ki = 13 nM
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CP0489363
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1-(2-cyclopropyl-6-(3-methylazetidin-1-yl)pyrimidin-4-yl)azepane
Show/Hide
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C17H26N4
|
1
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| 1 |
Ki = 13 nM
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CP0448586
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(R)-3-(1-benzyl-pyrrolidin-3-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C26H27N3O
|
1
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| 1 |
Ki = 13.3 nM
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CP0445628
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3-(1-(2-thienylmethyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C25H27N3OS
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1
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| 1 |
Ki = 13.4 nM
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CP0446349
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3-(1-(2-chlorobenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C27H28ClN3O
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1
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| 1 |
Ki = 13.8 nM
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CP0406016
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2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-2-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
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C24H31N3O2
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1
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| 1 |
Ki = 14 nM
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CP0437352
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(2R)-N-[1-[(5-aminopyridin-2-yl)methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C24H30F2N4O2
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1
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| 1 |
Ki = 15 nM
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CP0939855
|
3-(3,3-diphenylbut-1-ynyl)-3-methoxyquinuclidine
Show/Hide
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C24H27NO
|
1
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| 1 |
Ki = 15.85 nM
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CP0505389
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C24H34F2N2O2
|
1
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| 1 |
Ki = 16 nM
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CP0420691
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(R)-1-[4-(2-Amino-acetyl)-piperazin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C19H25F2N3O3
|
1
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| 1 |
Ki = 16 nM
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CP0393923
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6-(azocan-1-yl)-N,2-dicyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
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C18H28N4
|
1
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| 1 |
Ki = 16 nM
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CP0562091
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N,2-dicyclopropyl-5-methyl-6-(4-methylpiperidin-1-yl)pyrimidin-4-amine
Show/Hide
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C17H26N4
|
1
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| 1 |
Ki = 16 nM
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CP0425018
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3-(1-(4-chlorobenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C27H28ClN3O
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1
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| 1 |
Ki = 16.5 nM
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CP0451718
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3-(1-benzyl-piperidin-4-yl)-5,5-diphenyl-oxazolidin-2-one
Show/Hide
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C27H28N2O2
|
1
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| 1 |
Ki = 16.8 nM
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CP0448093
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2-(3,3-Difluoro-cyclopentyl)-2-hydroxy-N-[1-(3-hydroxymethyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C26H32F2N2O3
|
1
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| 1 |
Ki = 17 nM
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CP0506997
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N-[1-(cyclohexylmethyl)piperidin-4-yl]-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
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C25H38N2O2
|
1
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| 1 |
Ki = 17 nM
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CP0414993
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(R)-1-[1,4]Diazepan-1-yl-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C18H24F2N2O2
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1
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| 1 |
Ki = 17 nM
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CP0495916
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-piperidin-4-ylmethyl-acetamide
Show/Hide
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C19H26F2N2O2
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1
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| 1 |
Ki = 17 nM
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CP0380678
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(2R)-N-[1-(cyclohexylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C25H36F2N2O2
|
1
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| 1 |
Ki = 18 nM
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CP0402546
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2-Hydroxy-2-(3-hydroxy-cyclopentyl)-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C24H36N2O3
|
1
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| 1 |
Ki = 18 nM
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CP0505422
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1-(1-benzyl-piperidin-4-yl)-3-methyl-4,4-diphenyl-imidazolidin-2-one
Show/Hide
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C28H31N3O
|
1
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| 1 |
Ki = 18.5 nM
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CP0380626
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2-(3-Fluoro-cyclopentyl)-2-hydroxy-N-[1-(4-methyl-pent-3-enyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
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C24H35FN2O2
|
1
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| 1 |
Ki = 19 nM
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CP0413081
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1,3-benzodioxol-5-ylmethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C22H24N2O4
|
1
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| 1 |
Ki = 19 nM
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CP0551252
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1-(2-cyclopropyl-5-methyl-6-(3-methylazetidin-1-yl)pyrimidin-4-yl)azepane
Show/Hide
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C18H28N4
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1
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| 1 |
Ki = 20 nM
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CP0413078
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(3-fluoro-4-methylphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C22H25FN2O2
|
1
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| 1 |
Ki = 20 nM
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CP0381013
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(2R)-N-[1-[[3-(aminomethyl)phenyl]methyl]piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C26H33F2N3O2
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1
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| 1 |
Ki = 21 nM
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CP0875444
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(R)-N-((R)-piperidin-3-ylmethyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide trifluoroacetic acid
Show/Hide
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C39H45F3N4O5
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1
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| 1 |
Ki = 23 nM
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CP0398877
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(R)-cyclohexyl-[5-[(2S)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
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C22H29NO2
|
1
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| 1 |
Ki = 23.44 nM
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CP0858619
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2-(5-benzhydrylfuran-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H26INO
|
1
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| 1 |
Ki = 23.44 nM
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CP0379553
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6-(azepan-1-yl)-N-cyclopropyl-2-isopropyl-5-methylpyrimidin-4-amine
Show/Hide
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C17H28N4
|
1
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| 1 |
Ki = 25 nM
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CP0464729
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N,2-dicyclopropyl-6-(4,4-dimethylpiperidin-1-yl)-5-methylpyrimidin-4-amine
Show/Hide
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C18H28N4
|
1
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| 1 |
Ki = 25 nM
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CP0505423
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3-(1-(4-methoxybenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C28H31N3O2
|
1
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| 1 |
Ki = 25.8 nM
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CP0415133
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(R)-1-[4-(2-Amino-2-methyl-propyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C22H32F2N2O2
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1
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| 1 |
Ki = 26 nM
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CP0428350
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1-(1-benzyl-piperidin-4-yl)-3-benzyl-4-phenyl-imidazolidin-2-one
Show/Hide
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C28H31N3O
|
1
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| 1 |
Ki = 26.8 nM
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CP0393457
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(2R)-N-[1-(cycloheptylmethyl)piperidin-4-yl]-2-[(1R)-3,3-difluorocyclopentyl]-2-hydroxy-2-phenylacetamide
Show/Hide
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C26H38F2N2O2
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1
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| 1 |
Ki = 28 nM
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CP0854845
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(R)-N-(2-(piperidin-4-yl)ethyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide trifluoroacetic acid
Show/Hide
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C40H47F3N4O5
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1
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| 1 |
Ki = 29 nM
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CP0373261
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2-(3,3-Difluoro-cyclopentyl)-N-(1-furan-3-ylmethyl-piperidin-4-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
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C23H28F2N2O3
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1
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| 1 |
Ki = 30 nM
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CP0393910
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(-)-6-(azepan-1-yl)-N-cyclopropyl-5-methyl-2-(2-methylcyclopropyl)pyrimidin-4-amine
Show/Hide
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C18H28N4
|
1
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| 1 |
Ki = 32 nM
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CP0393925
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N,2-dicyclopropyl-6-(3,6-dihydro-2H-pyridin-1-yl)-5-methylpyrimidin-4-amine
Show/Hide
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C16H22N4
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1
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| 1 |
Ki = 32 nM
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CP0505263
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1-(2-cyclopropyl-6-(3,3-dimethylazetidin-1-yl)-5-methylpyrimidin-4-yl)azepane
Show/Hide
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C19H30N4
|
1
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| 1 |
Ki = 32 nM
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CP0388205
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2-[5-[cyclohexyl(phenyl)methyl]furan-2-yl]-1-methylpyrrolidine
Show/Hide
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C22H29NO
|
1
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| 1 |
Ki = 33.88 nM
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CP0917620
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2-(5-(hydroxydiphenylmethyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H26INO2
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1
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| 1 |
Ki = 36.31 nM
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CP0058613
|
CAS_132947
Show/Hide
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C64H77N13O6
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1
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| 1 |
Ki = 38.02 nM
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CP0393911
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6-(azepan-1-yl)-2-cyclobutyl-N-cyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
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C18H28N4
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1
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| 1 |
Ki = 40 nM
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CP0533071
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1-(6-(azepan-1-yl)-2-cyclopropyl-5-methylpyrimidin-4-yl)azepane
Show/Hide
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C20H32N4
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1
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| 1 |
Ki = 40 nM
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CP0551251
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1-(2-cyclopropyl-6-(3-methoxyazetidin-1-yl)-5-methylpyrimidin-4-yl)azepane
Show/Hide
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C18H28N4O
|
1
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| 1 |
Ki = 40 nM
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CP0406146
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1-[3-[4-[13-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]tridecyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C38H59N5O2S
|
1
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| 1 |
Ki = 44.67 nM
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CP0492334
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(R)-1-[4-(3-Amino-propyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C21H30F2N2O2
|
1
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| 1 |
Ki = 47 nM
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CP0942094
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(R)-N-((1S,2S)-2-aminocyclohexyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide trifluoroacetic acid
Show/Hide
|
C39H45F3N4O5
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1
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| 1 |
Ki = 48 nM
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CP0845758
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(R)-N-(piperidin-4-ylmethyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide trifluoroacetic acid
Show/Hide
|
C39H45F3N4O5
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1
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| 1 |
Ki = 49 nM
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CP0418889
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2-Cyclopentyl-N-(1-furan-3-ylmethyl-piperidin-4-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
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C23H30N2O3
|
1
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| 1 |
Ki = 50 nM
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CP0447972
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-1-piperazin-1-yl-ethanone
Show/Hide
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C17H22F2N2O2
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1
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| 1 |
Ki = 50 nM
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CP0393924
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N,2-dicyclopropyl-6-(4,4-difluoropiperidin-1-yl)-5-methylpyrimidin-4-amine
Show/Hide
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C16H22F2N4
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1
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| 1 |
Ki = 50 nM
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CP0442376
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N,2-dicyclopropyl-6-(4-ethylpiperidin-1-yl)-5-methylpyrimidin-4-amine
Show/Hide
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C18H28N4
|
1
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| 1 |
Ki = 50 nM
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CP0494678
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4-(azepan-1-yl)-2-cyclopropyl-5,6,7,8-tetrahydropyrido[2,3-d]pyrimidine
Show/Hide
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C16H24N4
|
1
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| 1 |
Ki = 50 nM
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CP0413083
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(3-fluoro-4-methoxyphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C22H25FN2O3
|
1
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| 1 |
Ki = 50 nM
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CP0378256
|
ethyl 7-benzyl-6-ethyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C31H32N2O4
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1
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| 1 |
Ki = 50.12 nM
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CP0428327
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3-(1-(3-trifluoromethylbenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C28H28F3N3O
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1
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| 1 |
Ki = 53.5 nM
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CP0413481
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1-[3-[4-[9-[1-[3-(2-oxo-3,4-dihydroquinolin-1-yl)propyl]piperidin-4-yl]nonyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C43H64N4O2
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1
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| 1 |
Ki = 57.54 nM
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CP0413077
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3-(3,4-dichlorophenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C23H26Cl2N2O2
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1
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| 1 |
Ki = 60 nM
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CP0413087
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1-azabicyclo[2.2.2]octan-3-yl N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C24H30N2O4
|
1
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| 1 |
Ki = 60 nM
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CP0858903
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(R)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C20H26INO2
|
1
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| 1 |
Ki = 61.66 nM
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CP0431859
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4-N,2-dicyclopropyl-6-N-[(2,6-difluorophenyl)methyl]-5-methylpyrimidine-4,6-diamine
Show/Hide
|
C18H20F2N4
|
1
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| 1 |
Ki = 63 nM
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CP0442371
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6-(azepan-1-yl)-N,2-dicyclopropylpyrimidin-4-amine
Show/Hide
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C16H24N4
|
1
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| 1 |
Ki = 63 nM
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CP0217520
|
AF-DX 384
Show/Hide
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C27H38N6O2
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1
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| 1 |
Ki = 66.07 nM
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CP0413082
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(3,4-dichlorophenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C21H22Cl2N2O2
|
1
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| 1 |
Ki = 70 nM
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CP0393079
|
ethyl 17-methoxy-7-methyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C26H30N2O4
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1
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| 1 |
Ki = 70.79 nM
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CP0404800
|
ethyl 17-methoxy-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C25H28N2O4
|
1
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| 1 |
Ki = 70.79 nM
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CP0875623
|
(R)-(6,6-Diphenyl-1,4-dioxan-2-yl)-N,N-dimethylmethanamine Oxalate
Show/Hide
|
C21H25NO6
|
1
|
| 1 |
Ki = 72.44 nM
|
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CP0437578
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(R)-1-[4-(4-Amino-butyl)-piperidin-1-yl]-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-ethanone
Show/Hide
|
C22H32F2N2O2
|
1
|
| 1 |
Ki = 76 nM
|
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CP0435432
|
N,2-dicyclopropyl-5-methyl-6-thiomorpholin-4-ylpyrimidin-4-amine
Show/Hide
|
C15H22N4S
|
1
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| 1 |
Ki = 79 nM
|
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CP0442373
|
4-N,2-dicyclopropyl-5-methyl-6-N-(2-thiophen-2-ylethyl)pyrimidine-4,6-diamine
Show/Hide
|
C17H22N4S
|
1
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| 1 |
Ki = 79 nM
|
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CP0483574
|
6-(azepan-1-yl)-2-cyclopentyl-N-cyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C19H30N4
|
1
|
| 1 |
Ki = 79 nM
|
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CP0562088
|
6-(azepan-1-yl)-N4,2-dicyclopropylpyrimidine-4,5-diamine
Show/Hide
|
C16H25N5
|
1
|
| 1 |
Ki = 79 nM
|
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CP0562090
|
N,2-dicyclopropyl-5-methyl-6-(4-methylidenepiperidin-1-yl)pyrimidin-4-amine
Show/Hide
|
C17H24N4
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0484305
|
1-(2-cyclopropyl-5-methyl-6-(piperidin-1-yl)pyrimidin-4-yl)azepane
Show/Hide
|
C19H30N4
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0509458
|
1-(6-(azetidin-1-yl)-2-cyclopropylpyrimidin-4-yl)azepane
Show/Hide
|
C16H24N4
|
1
|
| 1 |
Ki = 79 nM
|
|
|
|
CP0518106
|
(S)-3-(1-benzyl-pyrrolidin-3-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C26H27N3O
|
1
|
| 1 |
Ki = 82 nM
|
|
|
|
CP0435996
|
3-(1-(2-methoxybenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C28H31N3O2
|
1
|
| 1 |
Ki = 83.7 nM
|
|
|
|
CP0439204
|
2-(5-benzhydrylfuran-2-yl)-1-methylpyrrolidine
Show/Hide
|
C22H23NO
|
1
|
| 1 |
Ki = 85.11 nM
|
|
|
|
CP0376699
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-(2-piperidin-4-yl-ethyl)-acetamide
Show/Hide
|
C20H28F2N2O2
|
1
|
| 1 |
Ki = 89 nM
|
|
|
|
CP0440616
|
benzyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C21H24N2O2
|
1
|
| 1 |
Ki = 90 nM
|
|
|
|
CP0480403
|
ethyl 6-ethyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C24H26N2O4
|
1
|
| 1 |
Ki = 91.2 nM
|
|
|
|
CP0408530
|
N-[1-(cyclooctylmethyl)piperidin-4-yl]-2-cyclopentyl-2-hydroxy-2-phenylacetamide
Show/Hide
|
C27H42N2O2
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0391332
|
(R)-N-(3-Aminomethyl-phenyl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C20H22F2N2O2
|
1
|
| 1 |
Ki = 93 nM
|
|
|
|
CP0399526
|
1-[3-[4-[3-[[4-(1-methyl-3,6-dihydro-2H-pyridin-5-yl)-1,2,5-thiadiazol-3-yl]oxy]propyl]piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C28H39N5O2S
|
1
|
| 1 |
Ki = 93.33 nM
|
|
|
|
CP0431004
|
[5-(1-methylpyrrolidin-2-yl)furan-2-yl]-diphenylmethanol
Show/Hide
|
C22H23NO2
|
1
|
| 1 |
Ki = 95.5 nM
|
|
|
|
CP0467302
|
(R)-N-((S)-piperidin-3-ylmethyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide
Show/Hide
|
C37H44N4O3
|
1
|
| 1 |
Ki = 99 nM
|
|
|
|
CP0480004
|
2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-3-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0459891
|
ethyl 17-methylsulfanyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C25H28N2O3S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0429871
|
(R)-N-(4-Aminomethyl-cyclohexyl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C20H28F2N2O2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0393913
|
N,2-dicyclopropyl-5-ethyl-6-thiomorpholin-4-ylpyrimidin-4-amine
Show/Hide
|
C16H24N4S
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0403206
|
N,2-dicyclopropyl-5-methyl-6-[4-(trifluoromethyl)piperidin-1-yl]pyrimidin-4-amine
Show/Hide
|
C17H23F3N4
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0442374
|
N,2-dicyclopropyl-5-methyl-6-pyrrolidin-1-ylpyrimidin-4-amine
Show/Hide
|
C15H22N4
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0225899
|
AQ-RA 741
Show/Hide
|
C27H37N5O2
|
1
|
| 1 |
Ki = 100 nM
|
|
|
|
CP0428362
|
3-(1-Phenyl-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C26H27N3O
|
1
|
| 1 |
Ki = 101 nM
|
|
|
|
CP0496061
|
3-(1-benzyl-piperidin-4-yl)-5,5-di-(4-methoxyphenyl)-imidazolidin-2-one
Show/Hide
|
C29H33N3O3
|
1
|
| 1 |
Ki = 114 nM
|
|
|
|
CP0446350
|
3-(1-phenylethyl-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C28H31N3O
|
1
|
| 1 |
Ki = 117 nM
|
|
|
|
CP0376760
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-1-[4-(2-methylamino-ethyl)-piperidin-1-yl]-2-phenyl-ethanone
Show/Hide
|
C21H30F2N2O2
|
1
|
| 1 |
Ki = 120 nM
|
|
|
|
CP0442372
|
6-(azepan-1-yl)-N-cyclopropyl-2-(cyclopropylmethyl)-5-methylpyrimidin-4-amine
Show/Hide
|
C18H28N4
|
1
|
| 1 |
Ki = 126 nM
|
|
|
|
CP0453109
|
4-N,2-dicyclopropyl-5-methyl-6-N-(thiophen-2-ylmethyl)pyrimidine-4,6-diamine
Show/Hide
|
C16H20N4S
|
1
|
| 1 |
Ki = 126 nM
|
|
|
|
CP0416520
|
3-(3-fluoro-4-methylphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C24H29FN2O2
|
1
|
| 1 |
Ki = 130 nM
|
|
|
|
CP0413080
|
(1-methylpiperidin-4-yl) N-[2-(4-fluorophenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C21H25FN2O2
|
1
|
| 1 |
Ki = 140 nM
|
|
|
|
CP0875513
|
1-((S)-2-((R)-2-(4-(aminomethyl)piperidine-1-carbonyl)pyrrolidine-1-carbonyl)pyrrolidin-1-yl)-3,3,3-triphenylpropan-1-one trifluoroacetic acid
Show/Hide
|
C39H45F3N4O5
|
1
|
| 1 |
Ki = 150 nM
|
|
|
|
CP0067390
|
ethyl 6-butyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C26H30N2O4
|
1
|
| 1 |
Ki = 151.36 nM
|
|
|
|
CP0445630
|
3-(1-benzyl-piperidin-4-yl)-5,5-dibenzyl-imidazolidine-2,4-dione
Show/Hide
|
C29H33N3O
|
1
|
| 1 |
Ki = 152 nM
|
|
|
|
CP0859818
|
(R)-2-(5-((S)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
|
C23H32INO2
|
1
|
| 1 |
Ki = 154.88 nM
|
|
|
|
CP0442375
|
6-(8-azaspiro[4.5]decan-8-yl)-N,2-dicyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
|
C20H30N4
|
1
|
| 1 |
Ki = 158 nM
|
|
|
|
CP0505261
|
1-(6-(azepan-1-yl)-2-cyclopropyl-5-methylpyrimidin-4-yl)azetidin-3-ol
Show/Hide
|
C17H26N4O
|
1
|
| 1 |
Ki = 158 nM
|
|
|
|
CP0889249
|
(R)-N-(3-aminocyclohexyl)-1-((S)-1-(3,3,3-triphenylpropanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamide trifluoroacetic acid
Show/Hide
|
C39H45F3N4O5
|
1
|
| 1 |
Ki = 170 nM
|
|
|
|
CP0393595
|
2-Cyclopentyl-2-hydroxy-2-phenyl-N-(1-pyridin-4-ylmethyl-piperidin-4-yl)-acetamide
Show/Hide
|
C24H31N3O2
|
1
|
| 1 |
Ki = 190 nM
|
|
|
|
CP0514143
|
CAS_91533
Show/Hide
|
C20H24N2
|
1
|
| 1 |
Ki = 190.55 nM
|
|
|
|
CP0378645
|
1-[3-[4-(9-hydroxynonyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C26H42N2O2
|
1
|
| 1 |
Ki = 199.53 nM
|
|
|
|
CP0431860
|
6-N-benzyl-4-N,2-dicyclopropyl-5-methylpyrimidine-4,6-diamine
Show/Hide
|
C18H22N4
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0505260
|
1-(6-(3-bromoazetidin-1-yl)-2-cyclopropyl-5-methylpyrimidin-4-yl)azepane
Show/Hide
|
C17H25BrN4
|
1
|
| 1 |
Ki = 200 nM
|
|
|
|
CP0492196
|
ethyl 6-ethyl-17-methoxy-7-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
Ki = 218.78 nM
|
|
|
|
CP0393458
|
2-Cyclopentyl-2-hydroxy-N-[1-(2-methyl-benzyl)-piperidin-4-yl]-2-phenyl-acetamide
Show/Hide
|
C26H34N2O2
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0413079
|
3-(3,4-difluorophenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C23H26F2N2O2
|
1
|
| 1 |
Ki = 220 nM
|
|
|
|
CP0532144
|
3-(1-phenoxyethyl-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C28H31N3O2
|
1
|
| 1 |
Ki = 228 nM
|
|
|
|
CP0407747
|
ethyl 6-methyl-17-methylsulfanyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C23H24N2O3S
|
1
|
| 1 |
Ki = 229.09 nM
|
|
|
|
CP0425298
|
ethyl 7-methyl-17-methylsulfanyl-6-propyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C26H30N2O3S
|
1
|
| 1 |
Ki = 229.09 nM
|
|
|
|
CP0518455
|
3-(3-fluoro-4-methoxyphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C24H29FN2O3
|
1
|
| 1 |
Ki = 250 nM
|
|
|
|
CP0559327
|
6-(azepan-1-yl)-N,2-dicyclopropyl-5-fluoropyrimidin-4-amine
Show/Hide
|
C16H23FN4
|
1
|
| 1 |
Ki = 251 nM
|
|
|
|
CP0562089
|
4-N-benzyl-6-N,2-dicyclopropyl-4-N,5-dimethylpyrimidine-4,6-diamine
Show/Hide
|
C19H24N4
|
1
|
| 1 |
Ki = 251 nM
|
|
|
|
CP0416523
|
2-(3,4-dichlorophenyl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C22H24Cl2N2O2
|
1
|
| 1 |
Ki = 260 nM
|
|
|
|
CP0409101
|
ethyl 7-ethyl-17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C25H28N2O4
|
1
|
| 1 |
Ki = 263.03 nM
|
|
|
|
CP0374957
|
2-Cyclopentyl-N-(1-cyclopentylmethyl-piperidin-4-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C24H36N2O2
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0440621
|
[(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
Ki = 270 nM
|
|
|
|
CP0409139
|
ethyl 6-hexyl-17-methoxy-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C28H34N2O4
|
1
|
| 1 |
Ki = 281.84 nM
|
|
|
|
CP0480587
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-N-(2,3-dihydro-1H-isoindol-5-yl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
|
C21H22F2N2O2
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0416527
|
2-(1,3-benzodioxol-5-yl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C23H26N2O4
|
1
|
| 1 |
Ki = 290 nM
|
|
|
|
CP0416526
|
2-phenylethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C22H26N2O2
|
1
|
| 1 |
Ki = 300 nM
|
|
|
|
CP0403205
|
N,2-dicyclopropyl-6-(3,4-dihydro-1H-isoquinolin-2-yl)-5-methylpyrimidin-4-amine
Show/Hide
|
C20H24N4
|
1
|
| 1 |
Ki = 316 nM
|
|
|
|
CP0442370
|
6-(azepan-1-yl)-5-bromo-N,2-dicyclopropylpyrimidin-4-amine
Show/Hide
|
C16H23BrN4
|
1
|
| 1 |
Ki = 316 nM
|
|
|
|
CP0494679
|
6-N-cyclohexyl-4-N,2-dicyclopropyl-5-methylpyrimidine-4,6-diamine
Show/Hide
|
C17H26N4
|
1
|
| 1 |
Ki = 316 nM
|
|
|
|
CP0448605
|
(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-N-piperidin-4-yl-acetamide
Show/Hide
|
C18H24F2N2O2
|
1
|
| 1 |
Ki = 320 nM
|
|
|
|
CP0388200
|
(S)-cyclohexyl-[5-[(2R)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
|
C22H29NO2
|
1
|
| 1 |
Ki = 323.59 nM
|
|
|
|
CP0392351
|
ethyl 6-butyl-17-methylsulfanyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C26H30N2O3S
|
1
|
| 1 |
Ki = 338.84 nM
|
|
|
|
CP0413482
|
1-[3-[4-(13-hydroxytridecyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C30H50N2O2
|
1
|
| 1 |
Ki = 338.84 nM
|
|
|
|
CP0440614
|
(1-methylpiperidin-3-yl) N-[2-(4-fluorophenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C21H25FN2O2
|
1
|
| 1 |
Ki = 350 nM
|
|
|
|
CP0445629
|
3-(1-cyclohexylmethyl-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C27H35N3O
|
1
|
| 1 |
Ki = 354 nM
|
|
|
|
CP0411349
|
(1-methyl-4-phenylpiperidin-4-yl)methyl 3-(4-methoxyphenyl)propanoate
Show/Hide
|
C23H29NO3
|
1
|
| 1 |
Ki = 370 nM
|
|
|
|
CP0416517
|
3-(4-methoxyphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C24H30N2O3
|
1
|
| 1 |
Ki = 390 nM
|
|
|
|
CP0459833
|
2-(4-(pyrrolidin-1-yl)but-2-ynyl)isoxazolidin-3-one
Show/Hide
|
C11H16N2O2
|
1
|
| 1 |
Ki = 392 nM
|
|
|
|
CP0456479
|
(+)-6-(azepan-1-yl)-N-cyclopropyl-2-(2-methylcyclopropyl)pyrimidin-4-amine
Show/Hide
|
C17H26N4
|
1
|
| 1 |
Ki = 398 nM
|
|
|
|
CP0508164
|
6-N-cycloheptyl-4-N,2-dicyclopropyl-5-methylpyrimidine-4,6-diamine
Show/Hide
|
C18H28N4
|
1
|
| 1 |
Ki = 398 nM
|
|
|
|
CP0559326
|
N,2-dicyclopropyl-5-methoxy-6-thiomorpholin-4-ylpyrimidin-4-amine
Show/Hide
|
C15H22N4OS
|
1
|
| 1 |
Ki = 398 nM
|
|
|
|
CP0415357
|
methyl 17-methoxy-6,7-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C23H24N2O4
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0543664
|
N-ethyl-2,2-dimethyl-N-[3-[1-[2-oxo-2-(6-oxo-5H-benzo[b][1,4]benzodiazepin-11-yl)ethyl]piperidin-4-yl]propyl]pentanamide
Show/Hide
|
C32H44N4O3
|
1
|
| 1 |
Ki = 398.11 nM
|
|
|
|
CP0376946
|
prop-2-enyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C24H24N2O4
|
1
|
| 1 |
Ki = 407.38 nM
|
|
|
|
CP0425017
|
3-(1-(3-cyanobenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
|
C28H28N4O
|
1
|
| 1 |
Ki = 418 nM
|
|
|
|
CP0440618
|
2-(4-methoxyphenyl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
|
C23H28N2O3
|
1
|
| 1 |
Ki = 420 nM
|
|
|
|
CP0409449
|
4-Nitro-benzoic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester
Show/Hide
|
C14H16N2O4
|
1
|
| 1 |
Ki = 450 nM
|
|
|
|
CP0474634
|
ethyl 17-methoxy-6-pentyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C27H32N2O4
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1
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| 1 |
Ki = 457.09 nM
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CP0403207
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(1-(2-cyclopropyl-6-(cyclopropylamino)-5-methylpyrimidin-4-yl)piperidin-4-yl)methanol
Show/Hide
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C17H26N4O
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1
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| 1 |
Ki = 501 nM
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CP0403208
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1-(2-cyclopropyl-6-(cyclopropylamino)-5-methylpyrimidin-4-yl)piperidin-4-ol
Show/Hide
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C16H24N4O
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1
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| 1 |
Ki = 501 nM
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CP0431845
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6-(azepan-1-yl)-2-benzyl-N-cyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
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C21H28N4
|
1
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| 1 |
Ki = 501 nM
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CP0533070
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1-(2-cyclopropyl-6-(3-fluoroazetidin-1-yl)pyrimidin-4-yl)azepane
Show/Hide
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C16H23FN4
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1
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| 1 |
Ki = 501 nM
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CP0393635
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1-[3-[4-(2-phenylethyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C25H32N2O
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1
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| 1 |
Ki = 501.19 nM
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CP0860901
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(S)-2-(5-((S)-cyclohexyl(hydroxy)(phenyl)methyl)furan-2-yl)-1,1-dimethylpyrrolidinium iodide
Show/Hide
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C23H32INO2
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1
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| 1 |
Ki = 512.86 nM
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CP0003459
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3-(2-methoxyphenyl)-9-[3-[(4-methyl-5-phenyl-1,2,4-triazol-3-yl)sulfanyl]propyl]-3,9-diazaspiro[5.5]undecane
Show/Hide
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C28H37N5OS
|
1
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| 1 |
Ki = 514 nM
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CP0880166
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2-(4-Piperidin-1-ylbut-2-yn-1-yl)isoxazolidin-3-one oxalate
Show/Hide
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C14H20N2O6
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1
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| 1 |
Ki = 537 nM
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CP0416522
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3-phenylpropyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C23H28N2O2
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1
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| 1 |
Ki = 550 nM
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CP0469418
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(1-methylpiperidin-4-yl) N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C22H28N2O3
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1
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| 1 |
Ki = 570 nM
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CP0378643
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1-[3-[4-(11-hydroxyundecyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C28H46N2O2
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1
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| 1 |
Ki = 575.44 nM
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CP0393625
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1-[3-[4-(7-hydroxyheptyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C24H38N2O2
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1
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| 1 |
Ki = 630.96 nM
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CP0427780
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1-(6-(azepan-1-yl)-2-cyclopropyl-5-methylpyrimidin-4-yl)azetidin-3-one
Show/Hide
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C17H24N4O
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1
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| 1 |
Ki = 631 nM
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CP0381401
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2-(4-methoxyphenyl)ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
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C22H27NO3
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1
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| 1 |
Ki = 640 nM
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CP0409523
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(R)-N-(4-Aminomethyl-phenyl)-2-((R)-3,3-difluoro-cyclopentyl)-2-hydroxy-2-phenyl-acetamide
Show/Hide
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C20H22F2N2O2
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1
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| 1 |
Ki = 650 nM
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CP0085414
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(3aS,6R,6aS,9aR,9bR)-6-benzyl-1-methyl-3,3a,4,6,6a,7,8,9,9a,9b-decahydro-2H-benzo[de]quinolin-5-one
Show/Hide
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C20H27NO
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1
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| 1 |
Ki = 661 nM
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CP0480607
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(3S,3aS,4R,4aS,8aS,9aR)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 676.08 nM
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CP0392367
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prop-2-enyl 17-methoxy-7-[(4-methoxyphenyl)methyl]-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C32H32N2O5
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1
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| 1 |
Ki = 676.08 nM
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CP0020189
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6-acetoxy-8-azonia-bicyclo[3.2.1]octane
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C9H15NO2
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1
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| 1 |
Ki = 680 nM
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CP0494680
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6-(4-benzylpiperidin-1-yl)-N,2-dicyclopropyl-5-methylpyrimidin-4-amine
Show/Hide
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C23H30N4
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1
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| 1 |
Ki = 790 nM
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CP0540183
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1-(6-(azepan-1-yl)-2-cyclopropyl-5-methylpyrimidin-4-yl)azetidine-3-carbonitrile
Show/Hide
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C18H25N5
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1
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| 1 |
Ki = 794 nM
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CP0379402
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(3S,3aR,4S,4aR,8aR,9aS)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 794.33 nM
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CP0139206
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Arecaidine Propargyl Ester
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C10H13NO2
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1
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| 1 |
Ki = 851.14 nM
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CP0858932
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2-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]-1,2,3,4-tetrahydroisoquinoline methiodide
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C17H21IN2O2
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1
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| 1 |
Ki = 887 nM
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CP0377061
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ethyl 17-methoxy-6,7-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C24H26N2O4
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1
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| 1 |
Ki = 912.01 nM
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CP0435997
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3-(1-methyl-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C21H25N3O
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1
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| 1 |
Ki = 923 nM
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CP0399660
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-1-[4-(2-dimethylamino-ethyl)-piperidin-1-yl]-2-hydroxy-2-phenyl-ethanone
Show/Hide
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C22H32F2N2O2
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1
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| 1 |
Ki = 930 nM
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CP0416519
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(3,4-dimethoxyphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
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C23H28N2O4
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1
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| 1 |
Ki = 1020 nM
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CP0382995
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butyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C25H28N2O4
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1
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| 1 |
Ki = 1023.29 nM
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CP0532140
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3-(1-(4-imidazolylmethyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C24H27N5O
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1
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| 1 |
Ki = 1056 nM
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CP0451720
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3-(1-(3-pyridylmethyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C26H28N4O
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1
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| 1 |
Ki = 1132 nM
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CP0416518
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(4-methoxyphenyl)methyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C22H26N2O3
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1
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| 1 |
Ki = 1150 nM
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CP0232092
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1-[3-(4-butylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C21H32N2O
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1
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| 1 |
Ki = 1202.26 nM
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CP0459315
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(1-methylpiperidin-4-yl) N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C23H30N2O4
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1
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| 1 |
Ki = 1280 nM
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CP0374791
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Benzoic acid 8-aza-bicyclo[3.2.1]oct-6-yl ester
Show/Hide
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C14H17NO2
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1
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| 1 |
Ki = 1300 nM
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CP0440617
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(1-methylpiperidin-3-yl) N-[2-(4-methoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C22H28N2O3
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1
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| 1 |
Ki = 1320 nM
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CP0411640
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1-[3-(4-pentylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C22H34N2O
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1
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| 1 |
Ki = 1348.96 nM
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CP0392482
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benzyl 17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C28H26N2O4
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1
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| 1 |
Ki = 1380.38 nM
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CP0858930
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5-phenyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]isoxazole methiodide
Show/Hide
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C18H21IN2O2
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1
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| 1 |
Ki = 1448 nM
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CP0401417
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3-(4-methoxyphenyl)-N-[(1-methyl-4-phenylpiperidin-4-yl)methyl]propanamide
Show/Hide
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C23H30N2O2
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1
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| 1 |
Ki = 1540 nM
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CP0440620
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3-(3,4-dimethoxyphenyl)propyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C25H32N2O4
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1
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| 1 |
Ki = 1560 nM
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CP0502455
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(3S,3aS,4R,4aS,8aS,9aR)-4-[(E)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 1621.81 nM
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CP0541756
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3-(1-phenylpropyl-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C29H33N3O
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1
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| 1 |
Ki = 1630 nM
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CP0443229
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(S)-cyclohexyl-[5-[(2S)-1-methylpyrrolidin-2-yl]furan-2-yl]-phenylmethanol
Show/Hide
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C22H29NO2
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1
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| 1 |
Ki = 1659.59 nM
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CP0403333
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-3-ylmethylidene)indene-1-carboxylate
Show/Hide
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C23H22N2O2
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1
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| 1 |
Ki = 1698.24 nM
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CP0378979
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-2-ylmethylidene)indene-1-carboxylate
Show/Hide
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C23H22N2O2
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1
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| 1 |
Ki = 1737.8 nM
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CP0378647
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1-[3-[4-(5-hydroxypentyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C22H34N2O2
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1
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| 1 |
Ki = 1905.46 nM
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CP0381042
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(3S,3aR,4R,4aS,8aR,9aS)-4-[(Z)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 1949.84 nM
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CP0377555
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5-benzyl-17-methoxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene
Show/Hide
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C27H26N2O2
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1
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| 1 |
Ki = 2041.74 nM
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CP0428361
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3-(1-(3-trifluoromethoxybenzyl)-piperidin-4-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C28H28F3N3O2
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1
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| 1 |
Ki = 2057 nM
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CP0467135
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1-azabicyclo[2.2.2]octan-3-yl (3E)-3-(pyridin-4-ylmethylidene)indene-1-carboxylate
Show/Hide
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C23H22N2O2
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1
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| 1 |
Ki = 2089.3 nM
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CP0403577
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(3S,3aR,4S,4aR,8aR,9aS)-4-[(E)-2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethenyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
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C22H35NO2
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1
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| 1 |
Ki = 2089.3 nM
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CP0541755
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3-(1-benzylpiperidin-4-yl)-5,5-diphenyl-imidazolidin-2,4-dione
Show/Hide
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C27H27N3O2
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1
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| 1 |
Ki = 2185 nM
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CP0447909
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2-(4-methoxyphenyl)ethyl N-[(1-methyl-4-phenylpiperidin-4-yl)methyl]carbamate
Show/Hide
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C23H30N2O3
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1
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| 1 |
Ki = 2300 nM
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CP0393633
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1-[3-(4-propylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
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C20H30N2O
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1
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| 1 |
Ki = 2344.23 nM
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CP0233820
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2-benzyl-6-(3-methoxyphenyl)-3,4-dihydro-1H-isoquinoline
Show/Hide
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C23H23NO
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1
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| 1 |
Ki = 2369 nM
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CP0848084
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[4-(4-chloro-phenylcarbamoyloxy)-but-2-ynyl]-trimethyl-ammonium chloride
Show/Hide
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C14H18Cl2N2O2
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1
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| 1 |
Ki = 2398.83 nM
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CP0773921
|
SID50106034
Show/Hide
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C14H18Cl2N2O2
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1
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| 1 |
Ki = 2398.83 nM
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CP0423369
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(McN-A-343) [4-(3-Chloro-phenylcarbamoyloxy)-but-2-ynyl]-trimethyl-ammonium; chloride
Show/Hide
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C14H18ClN2O2+
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1
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| 1 |
Ki = 2398.83 nM
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CP0376666
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(R)-2-((R)-3,3-Difluoro-cyclopentyl)-2-hydroxy-2-phenyl-1-[4-(2-piperidin-1-yl-ethyl)-piperidin-1-yl]-ethanone
Show/Hide
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C25H36F2N2O2
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1
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| 1 |
Ki = 2400 nM
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CP0448585
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3-(1-benzyl-piperidin-3-yl)-5,5-diphenyl-imidazolidin-2-one
Show/Hide
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C27H29N3O
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1
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| 1 |
Ki = 2445 nM
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CP0540265
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6-(azepan-1-yl)-N,2-dicyclopropyl-5-nitropyrimidin-4-amine
Show/Hide
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C16H23N5O2
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1
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| 1 |
Ki = 2512 nM
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CP0415400
|
Cevimeline
Show/Hide
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C10H17NOS
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1
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| 1 |
Ki = 2570.4 nM
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CP0870440
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(S)-1,1-Dimethyl-2-(5-methyl-furan-2-yl)-pyrrolidinium
Show/Hide
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C11H18INO
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1
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| 1 |
Ki = 2691.53 nM
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CP0244206
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7-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]thieno[2,3-c]pyridine
Show/Hide
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C21H12F3N3OS
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1
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| 1 |
Ki = 2700 nM
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CP0404711
|
ethyl 17-chloro-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
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C22H21ClN2O3
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1
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| 1 |
Ki = 2754.23 nM
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CP0895036
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2-(2-Furyl)-1-methylpyrrolidineMethiodide
Show/Hide
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C10H16INO
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1
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| 1 |
Ki = 2754.23 nM
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CP0413086
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2-(3,4-dimethoxyphenyl)ethyl N-(1-azabicyclo[2.2.2]octan-3-yl)-N-phenylcarbamate
Show/Hide
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C24H30N2O4
|
1
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| 1 |
Ki = 2760 nM
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CP0413085
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[(1R,5R)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl] N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
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C25H32N2O4
|
1
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| 1 |
Ki = 2800 nM
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CP0440485
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(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) cyclohexanecarboxylate
Show/Hide
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C15H25NO2
|
1
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| 1 |
Ki = 3000 nM
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CP0116478
|
1-[3-(4-benzylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H30N2O
|
1
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| 1 |
Ki = 3019.95 nM
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CP0402148
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17-methoxy-6-methyl-5-(3-methyl-1,2,4-oxadiazol-5-yl)-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene
Show/Hide
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C23H22N4O3
|
1
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| 1 |
Ki = 3090.3 nM
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CP0404340
|
Benzoic acid 8-methyl-8-aza-bicyclo[3.2.1]oct-6-yl ester
Show/Hide
|
C15H19NO2
|
1
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| 1 |
Ki = 3200 nM
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CP0483576
|
1-(2-cyclopropyl-6-(cyclopropylamino)-5-methylpyrimidin-4-yl)piperidin-4-one
Show/Hide
|
C16H22N4O
|
1
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| 1 |
Ki = 3200 nM
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CP0381400
|
N-[2-(4-methoxyphenyl)ethyl]-1-methyl-4-phenylpiperidine-4-carboxamide
Show/Hide
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C22H28N2O2
|
1
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| 1 |
Ki = 3290 nM
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CP0392743
|
(3S,3aR,4R,4aS,8aR,9aS)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
|
C22H33NO2
|
1
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| 1 |
Ki = 3311.31 nM
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CP0845388
|
Cis-N,N,N-trimethyl-1-((2R,6S)-6-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
2
|
| 1 |
Ki = 3388.44 nM
|
|
|
| 2 |
Ki = 7585.78 nM
|
|
|
|
CP0530916
|
1-[2-(4-methoxyphenyl)ethyl]-3-[(1-methyl-4-phenylpiperidin-4-yl)methyl]urea
Show/Hide
|
C23H31N3O2
|
1
|
| 1 |
Ki = 3550 nM
|
|
|
|
CP0880168
|
1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]piperidine oxalate
Show/Hide
|
C14H20N2O6
|
1
|
| 1 |
Ki = 3919 nM
|
|
|
|
CP0900137
|
N,N-dimethyl-4-[(5-methylisoxazol-3-yl)oxy]but-2-yn-1-amine methiodide
Show/Hide
|
C11H17IN2O2
|
1
|
| 1 |
Ki = 3995 nM
|
|
|
|
CP0858931
|
5-phenyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]-isoxazole fumarate
Show/Hide
|
C21H22N2O6
|
1
|
| 1 |
Ki = 4013 nM
|
|
|
|
CP0374693
|
(1-methyl-4-phenylpiperidin-4-yl)methyl N-[2-(3,4-dimethoxyphenyl)ethyl]carbamate
Show/Hide
|
C24H32N2O4
|
1
|
| 1 |
Ki = 4030 nM
|
|
|
|
CP0440615
|
(1-methylpiperidin-3-yl) N-[2-(3,4-dimethoxyphenyl)ethyl]-N-phenylcarbamate
Show/Hide
|
C23H30N2O4
|
1
|
| 1 |
Ki = 4360 nM
|
|
|
|
CP0374692
|
(1-methyl-4-phenylpiperidin-4-yl)methyl 3-(3,4-dimethoxyphenyl)propanoate
Show/Hide
|
C24H31NO4
|
1
|
| 1 |
Ki = 4600 nM
|
|
|
|
CP0489929
|
1-[3-(4-phenylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C23H28N2O
|
1
|
| 1 |
Ki = 4677.35 nM
|
|
|
|
CP0880167
|
1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]piperidine methiodide
Show/Hide
|
C13H21IN2O2
|
1
|
| 1 |
Ki = 4740 nM
|
|
|
|
CP0408533
|
(3S,3aR,4S,4aR,8aR,9aS)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
|
C22H33NO2
|
1
|
| 1 |
Ki = 5011.87 nM
|
|
|
|
CP0377554
|
ethyl 15-chloro-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C22H21ClN2O3
|
1
|
| 1 |
Ki = 5128.61 nM
|
|
|
|
CP0374691
|
2-(3,4-dimethoxyphenyl)ethyl 1-methyl-4-phenylpiperidine-4-carboxylate
Show/Hide
|
C23H29NO4
|
1
|
| 1 |
Ki = 5260 nM
|
|
|
|
CP0876609
|
1-[4-(4,5-dihydroisoxazol-3-yloxy)but-2-yn-1-yl]indoline methiodide
Show/Hide
|
C16H19IN2O2
|
1
|
| 1 |
Ki = 5539 nM
|
|
|
|
CP0249974
|
5-methylfurmethide
Show/Hide
|
C9H16NO+
|
1
|
| 1 |
Ki = 6165.95 nM
|
|
|
|
CP0393626
|
1-[3-[4-(2-phenylethyl)piperazin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C24H31N3O
|
1
|
| 1 |
Ki = 6606.93 nM
|
|
|
|
CP0374663
|
(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) 2,2,2-trichloroethyl carbonate
Show/Hide
|
C11H16Cl3NO3
|
1
|
| 1 |
Ki = 6700 nM
|
|
|
|
CP0472845
|
1-[3-(4-benzylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C23H29N3O
|
1
|
| 1 |
Ki = 6760.83 nM
|
|
|
|
CP0895034
|
2-(5-Methyl-2-furyl)-1-methylpyrrolidine Methiodide
Show/Hide
|
C11H18INO
|
1
|
| 1 |
Ki = 6918.31 nM
|
|
|
|
CP0411642
|
1-[3-(4-butylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C20H31N3O
|
1
|
| 1 |
Ki = 7079.46 nM
|
|
|
|
CP0873039
|
5-methyl-3-[(4-pyrrolidin-1-ylbut-2-yn-1-yl)oxy]isoxazole methiodide
Show/Hide
|
C13H19IN2O2
|
1
|
| 1 |
Ki = 7386 nM
|
|
|
|
CP0377264
|
(8-methyl-8-azabicyclo[3.2.1]octan-6-yl) propanoate
Show/Hide
|
C11H19NO2
|
1
|
| 1 |
Ki = 7400 nM
|
|
|
|
CP0383280
|
8-azabicyclo[3.2.1]octan-6-yl cyclohexanecarboxylate
Show/Hide
|
C14H23NO2
|
1
|
| 1 |
Ki = 7500 nM
|
|
|
|
CP0845041
|
(R)-1,1-Dimethyl-2-(5-methyl-furan-2-yl)-pyrrolidinium
Show/Hide
|
C11H18INO
|
1
|
| 1 |
Ki = 7762.47 nM
|
|
|
|
CP0878023
|
Cis-((2R*,6S*)-6-Benzhydryl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C21H28INO2
|
1
|
| 1 |
Ki = 8912.51 nM
|
|
|
|
CP0064188
|
4-[4-(6-methylimidazo[1,2-a]pyrazin-5-yl)-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
Show/Hide
|
C21H13F3N4O2
|
1
|
| 1 |
Ki = 9200 nM
|
|
|
|
CP0916821
|
Cis-N,N,N-Trimethyl((2R*,6S*)-6-phenyl-1,4-dioxan-2-yl)methanaminium Iodide
Show/Hide
|
C14H22INO2
|
1
|
| 1 |
Ki = 9772.37 nM
|
|
|
|
CP0410895
|
2-(dimethylamino)ethyl (3E)-3-(pyridin-3-ylmethylidene)indene-1-carboxylate
Show/Hide
|
C20H20N2O2
|
1
|
| 1 |
Ki = 10000 nM
|
|
|
|
CP0897808
|
N,N-dimethyl-4-[(5-methylisoxazol-3-yl)oxy]-but-2-yn-1-amine fumarate
Show/Hide
|
C14H18N2O6
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002070
|
1-(1H-Indol-3-yl)-2-propanamine
Show/Hide
|
C11H14N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0002071
|
N-[2-(5-methoxy-1H-indol-3-yl)ethyl]-N-prop-2-enylprop-2-en-1-amine
Show/Hide
|
C17H22N2O
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0635067
|
2-amino-6-chloro-3,4-dihydroquinazoline hydrochloride
Show/Hide
|
C8H9Cl2N3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0431550
|
1-[2-(3,4-dimethoxyphenyl)ethyl]-3-[(1-methyl-4-phenylpiperidin-4-yl)methyl]urea
Show/Hide
|
C24H33N3O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0447908
|
N-[2-(3,4-dimethoxyphenyl)ethyl]-1-methyl-4-phenylpiperidine-4-carboxamide
Show/Hide
|
C23H30N2O3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0054519
|
(1R,12R,13S,17R,21S)-12-ethyl-18-propyl-7-(trifluoromethyl)-10,18-diazapentacyclo[11.7.1.02,11.04,9.017,21]henicosa-2(11),3,5,7,9-pentaene
Show/Hide
|
C25H31F3N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0387083
|
(3aS,9bS)-3a-methyl-5-phenyl-2,3,4,9b-tetrahydro-1H-pyrrolo[2,3-c]quinoline
Show/Hide
|
C18H20N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391120
|
(1S,2R)-1-ethyl-7-methoxy-2-methyl-3,4-dihydro-1H-naphthalen-2-amine
Show/Hide
|
C14H21NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391121
|
(3S,4S)-4-ethyl-3,6-dimethyl-2,4-dihydrochromen-3-amine
Show/Hide
|
C13H19NO
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0391154
|
(3aS,9bS)-7,9-dimethoxy-3a-methyl-2,3,4,9b-tetrahydro-1H-chromeno[3,4-b]pyrrole
Show/Hide
|
C14H19NO3
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0411059
|
(3S,4S)-4-ethyl-3-methyl-1-phenyl-2,4-dihydroquinolin-3-amine
Show/Hide
|
C18H22N2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0064183
|
4-[3-methyl-4-(6-methylimidazo[1,2-a]pyrazin-5-yl)phenoxy]furo[3,2-c]pyridine
Show/Hide
|
C21H16N4O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0369306
|
4-[4-imidazo[1,2-a]pyridin-5-yl-3-(trifluoromethyl)phenoxy]furo[3,2-c]pyridine
Show/Hide
|
C21H12F3N3O2
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0127400
|
(-)-Pramipexole
Show/Hide
|
C10H17N3S
|
1
|
| 1 |
Ki > 10000 nM
|
|
|
|
CP0902206
|
N,N,N-Trimethyl((2R*,5S*)-5,6,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C11H24INO2
|
1
|
| 1 |
Ki = 10471.29 nM
|
|
|
|
CP0418924
|
(3S,3aS,4R,4aS,8aS,9aR)-4-[2-[(2R,6S)-1,6-dimethylpiperidin-2-yl]ethynyl]-3-methyl-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-3H-benzo[f][2]benzofuran-1-one
Show/Hide
|
C22H33NO2
|
1
|
| 1 |
Ki = 10964.78 nM
|
|
|
|
CP0859714
|
((2R*,5S*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki = 10964.78 nM
|
|
|
|
CP0377860
|
8-azabicyclo[3.2.1]octan-6-yl propanoate
Show/Hide
|
C10H17NO2
|
1
|
| 1 |
Ki = 11400 nM
|
|
|
|
CP0497956
|
2-(furan-2-yl)pyrrolidine
Show/Hide
|
C8H11NO
|
1
|
| 1 |
Ki = 11481.54 nM
|
|
|
|
CP0379138
|
1-[3-[4-(3-hydroxypropyl)piperidin-1-yl]propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C20H30N2O2
|
1
|
| 1 |
Ki = 11748.98 nM
|
|
|
|
CP0509683
|
(2R)-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 12022.64 nM
|
|
|
|
CP0848059
|
SID855871
Show/Hide
|
C8H18INO2
|
1
|
| 1 |
Ki = 13489.63 nM
|
|
|
|
CP0393421
|
2-(dimethylamino)ethyl (3E)-3-(pyridin-2-ylmethylidene)indene-1-carboxylate
Show/Hide
|
C20H20N2O2
|
1
|
| 1 |
Ki = 14125.38 nM
|
|
|
|
CP0393627
|
1-[3-(4-methylpiperidin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C18H26N2O
|
1
|
| 1 |
Ki = 14125.38 nM
|
|
|
|
CP0024400
|
6-acetoxy-8-methyl-8-azonia-bicyclo[3.2.1]octane
Show/Hide
|
C10H17NO2
|
1
|
| 1 |
Ki = 15000 nM
|
|
|
|
CP0379047
|
2-(dimethylamino)ethyl (3E)-3-(pyridin-4-ylmethylidene)indene-1-carboxylate
Show/Hide
|
C20H20N2O2
|
1
|
| 1 |
Ki = 15135.61 nM
|
|
|
|
CP0376953
|
N-ethyl-17-methoxy-N,6-dimethyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxamide
Show/Hide
|
C24H27N3O3
|
1
|
| 1 |
Ki = 15488.17 nM
|
|
|
|
CP0859660
|
N,N,N-Trimethyl((2R*,5R*)-5,6,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C11H24INO2
|
1
|
| 1 |
Ki = 16218.1 nM
|
|
|
|
CP0910892
|
(R)-2-Furan-2-yl-1,1-dimethyl-pyrrolidinium
Show/Hide
|
C10H16INO
|
1
|
| 1 |
Ki = 17782.79 nM
|
|
|
|
CP0877929
|
Cis-((2R*,6S*)-6-Ethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki = 17782.79 nM
|
|
|
|
CP0232093
|
1-[3-(4-phenylpiperazin-1-yl)propyl]-3,4-dihydroquinolin-2-one
Show/Hide
|
C22H27N3O
|
1
|
| 1 |
Ki = 17782.79 nM
|
|
|
|
CP0021606
|
8-Aza-bicyclo[3.2.1]octane-6-carboxylic acid methyl ester
Show/Hide
|
C9H15NO2
|
1
|
| 1 |
Ki = 18000 nM
|
|
|
|
CP0876494
|
2-(5-Methyl-2-furyl)-pyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 18197.01 nM
|
|
|
|
CP0409674
|
N,N-dimethyl-2-[(3E)-3-(pyridin-2-ylmethylidene)inden-1-yl]ethanamine
Show/Hide
|
C19H20N2
|
1
|
| 1 |
Ki = 21379.62 nM
|
|
|
|
CP0859477
|
(6,6-Dimethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki = 21379.62 nM
|
|
|
|
CP0895035
|
(S)-2-Furan-2-yl-1,1-dimethyl-pyrrolidinium
Show/Hide
|
C10H16INO
|
1
|
| 1 |
Ki = 21379.62 nM
|
|
|
|
CP0895136
|
Trans-((2R*,6R*)-6-Benzhydryl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C21H28INO2
|
1
|
| 1 |
Ki = 21379.62 nM
|
|
|
|
CP0898948
|
2-(5-Methyl-2-furyl)-1-methylpyrrolidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
Ki = 22908.68 nM
|
|
|
|
CP0474436
|
trimethyl-[[(2S,6S)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide
Show/Hide
|
C9H20NO2+
|
1
|
| 1 |
Ki = 23442.29 nM
|
|
|
|
CP0372804
|
(2R)-2-(furan-2-yl)pyrrolidine
Show/Hide
|
C8H11NO
|
1
|
| 1 |
Ki = 25118.86 nM
|
|
|
|
CP0431291
|
ethyl 17-hydroxy-6-methyl-12-oxa-1,7-diazapentacyclo[11.8.0.03,11.04,8.014,19]henicosa-3(11),4(8),5,9,14(19),15,17-heptaene-5-carboxylate
Show/Hide
|
C22H22N2O4
|
1
|
| 1 |
Ki = 25703.96 nM
|
|
|
|
CP0848060
|
(R)-1-(1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
|
C8H18INO2
|
1
|
| 1 |
Ki = 26915.35 nM
|
|
|
|
CP0449315
|
N,N-dimethyl-2-[(3E)-3-(pyridin-3-ylmethylidene)inden-1-yl]ethanamine
Show/Hide
|
C19H20N2
|
1
|
| 1 |
Ki = 27542.29 nM
|
|
|
|
CP0372904
|
(2R)-1-methyl-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
Ki = 28840.32 nM
|
|
|
|
CP0401297
|
3-(3,4-dimethoxyphenyl)-N-[(1-methyl-4-phenylpiperidin-4-yl)methyl]propanamide
Show/Hide
|
C24H32N2O3
|
1
|
| 1 |
Ki > 30000 nM
|
|
|
|
CP0875624
|
Trans-N,N,N-Trimethyl((2R*,6R*)-6-phenyl-1,4-dioxan-2-yl)methanaminium Iodide
Show/Hide
|
C14H22INO2
|
1
|
| 1 |
Ki = 31622.78 nM
|
|
|
|
CP0845387
|
N,N,N-Trimethyl((2R*,6S*)-5,5,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C11H24INO2
|
1
|
| 1 |
Ki = 32359.37 nM
|
|
|
|
CP0433872
|
(2S)-1-methyl-2-(5-methylfuran-2-yl)pyrrolidine
Show/Hide
|
C10H15NO
|
1
|
| 1 |
Ki = 33113.11 nM
|
|
|
|
CP0455031
|
(2R,3R,5R)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki = 33884.42 nM
|
|
|
|
CP0859716
|
()-(2R,6R)-N,N,N-trimethyl(6-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
2
|
| 1 |
Ki = 35481.34 nM
|
|
|
| 2 |
Ki = 61659.5 nM
|
|
|
|
CP0371717
|
trimethyl-[[(2S,6R)-6-methyl-1,4-dioxan-2-yl]methyl]azanium;iodide
Show/Hide
|
C9H20NO2+
|
1
|
| 1 |
Ki = 36307.81 nM
|
|
|
|
CP0430112
|
(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-3-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C20H21N3O
|
1
|
| 1 |
Ki = 40738.03 nM
|
|
|
|
CP0916016
|
N,N,N-Trimethyl(5,5,6,6-tetramethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C12H26INO2
|
1
|
| 1 |
Ki = 40738.03 nM
|
|
|
|
CP0372805
|
(2S)-2-(furan-2-yl)pyrrolidine
Show/Hide
|
C8H11NO
|
1
|
| 1 |
Ki = 43651.58 nM
|
|
|
|
CP0859713
|
(2R*,5S*)-N,N,N-Trimethyl-(5-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki = 44668.36 nM
|
|
|
|
CP0910891
|
2-(2-Furyl)-1-methylpyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 44668.36 nM
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CP0393373
|
(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-4-ylmethylidene)indene-1-carboxamide
Show/Hide
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C20H21N3O
|
1
|
| 1 |
Ki = 45708.82 nM
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CP0859717
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N,N,N-Trimethyl((2R*,6R*)-5,5,6-trimethyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
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C11H24INO2
|
1
|
| 1 |
Ki = 46773.51 nM
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CP0500729
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(2S)-2-(furan-2-yl)-1-methylpyrrolidine
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C9H13NO
|
1
|
| 1 |
Ki = 52480.75 nM
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CP0429992
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(3E)-N-[2-(dimethylamino)ethyl]-3-(pyridin-2-ylmethylidene)indene-1-carboxamide
Show/Hide
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C20H21N3O
|
1
|
| 1 |
Ki = 61659.5 nM
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CP0374978
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(3E)-N-[2-(dimethylamino)ethyl]-N-methyl-3-(pyridin-2-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
Ki = 63095.73 nM
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CP0864337
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N,N,N-trimethyl-1-((2R,5R)-5-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki = 66069.34 nM
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CP0405252
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(3E)-N-[2-(dimethylamino)ethyl]-N-methyl-3-(pyridin-3-ylmethylidene)indene-1-carboxamide
Show/Hide
|
C21H23N3O
|
1
|
| 1 |
Ki = 72443.6 nM
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|
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CP0868051
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(5,5-Dimethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki = 77624.71 nM
|
|
|
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CP0465871
|
(2R)-2-(furan-2-yl)-1-methylpyrrolidine
Show/Hide
|
C9H13NO
|
1
|
| 1 |
Ki = 81283.05 nM
|
|
|
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CP0867621
|
Trans-((2R*,6R*)-6-Ethyl-1,4-dioxan-2-yl)-N,N,N-trimethylmethanaminium Iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki = 81283.05 nM
|
|
|
|
CP0377730
|
(4-methylpiperazin-1-yl)-[(3E)-3-(pyridin-4-ylmethylidene)inden-1-yl]methanone
Show/Hide
|
C21H21N3O
|
1
|
| 1 |
Ki = 97723.72 nM
|
|
|
|
CP0859476
|
((2S*,5S*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0859715
|
((2R*,5R*,6S*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0904026
|
((2R*,5S*,6R*)-5,6-Dimethyl-1,4-dioxan-2-yl)-N,N,Ntrimethylmethanaminium iodide
Show/Hide
|
C10H22INO2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0407014
|
(5S,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone
Show/Hide
|
C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0414425
|
(5R,2'S)-5-(1-methyl-2-pyrrolidinyl)oxazolidinone
Show/Hide
|
C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0846921
|
(S)-N,N,N-trimethyl-1-(2-oxooxazolidin-5-yl)methanaminium
Show/Hide
|
C7H15N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0846922
|
(S)-2-(carbamoyloxymethyl)-1,1-dimethylpyrrolidinium
Show/Hide
|
C8H17N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0846927
|
(R)-5-((dimethylamino)methyl)oxazolidin-2-one
Show/Hide
|
C6H12N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0848614
|
(S)-5-((dimethylamino)methyl)-3-methyloxazolidin-2-one
Show/Hide
|
C7H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0856191
|
(S)-(1-methylpyrrolidin-2-yl)methyl carbamate
Show/Hide
|
C7H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0860582
|
(R)-N,N,N-trimethyl-1-(3-methyl-2-oxooxazolidin-5-yl)methanaminium
Show/Hide
|
C8H17N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0861363
|
(S)-N,N,N-trimethyl-1-(3-methyl-2-oxooxazolidin-5-yl)methanaminium
Show/Hide
|
C8H17N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0866588
|
(R)-N,N,N-trimethyl-1-(2-oxooxazolidin-5-yl)methanaminium
Show/Hide
|
C7H15N2O2+
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0886638
|
(R)-4-((S)-1-methylpyrrolidin-2-yl)oxazolidin-2-one
Show/Hide
|
C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0902643
|
(R)-5-((dimethylamino)methyl)-3-methyloxazolidin-2-one
Show/Hide
|
C7H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0902877
|
(S)-5-((dimethylamino)methyl)oxazolidin-2-one
Show/Hide
|
C6H12N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0912137
|
(S)-4-((S)-1-methylpyrrolidin-2-yl)oxazolidin-2-one
Show/Hide
|
C8H14N2O2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0848040
|
(R)-N,N,N-Trimethyl-1-(2-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0866923
|
N,N,N-trimethyl-1-((2R,3S)-3-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0913147
|
N,N,N-trimethyl-1-((2R,3R)-3-methyl-1,4-dioxan-2-yl)methanaminium iodide
Show/Hide
|
C9H20INO2
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0425884
|
2-(3,4-dimethoxyphenyl)ethyl 1-methyl-4-phenyl-3,6-dihydro-2H-pyridine-5-carboxylate
Show/Hide
|
C23H27NO4
|
1
|
| 1 |
Ki > 100000 nM
|
|
|
|
CP0307921
|
N-[4-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]butyl]-1-benzothiophene-2-sulfonamide
Show/Hide
|
C24H26FN3O3S2
|
1
|
| 1 |
Ki > 1000 nM
|
|
|
|
CP0379516
|
(2S,3R,5S)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379517
|
(2R,3S,5R)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379521
|
(2R,3S,5R)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379525
|
(2S,3R,5S)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379526
|
(2R,3R,5R)-5-[(2R)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0379527
|
(2S,3S,5S)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0419569
|
(2R,3S,5R)-5-[(2R)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0419583
|
(2S,3R,5S)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0424750
|
(2R,3R,5R)-2-methyl-5-[(2R)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0431823
|
(2R,3S,5R)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0432602
|
(2R,3R,5R)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0449147
|
(2S,3S,5S)-2-methyl-5-[(2S)-1-methylpyrrolidin-2-yl]-1,3-oxathiolane 3-oxide
Show/Hide
|
C9H17NO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
|
CP0461163
|
(2S,3S,5S)-5-[(2S)-1,1-dimethylpyrrolidin-1-ium-2-yl]-2-methyl-1,3-oxathiolane 3-oxide;iodide
Show/Hide
|
C10H20INO2S
|
1
|
| 1 |
Ki < 100000 nM
|
|
|
