Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3-endo)-3-(2-Cyano-2,2-diphenylethyl)-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane Bromide
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Canonical SMILES
C[N+]1(C)[C@@H]2CC[C@H]1C[C@@H](CC(C#N)(c1ccccc1)c1ccccc1)C2.[Br-]
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Compound Formula C24H29BrN2
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P20309
Gene Name
CHRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
IC50 < 10 nM
   TI
   LI
   LO
   TS
2
Kd = 0.01995 nM
   TI
   LI
   LO
   TS
3
Ki = 0.06 nM
   TI
   LI
   LO
   TS
4
Ki = 0.0631 nM
   TI
   LI
   LO
   TS