Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-N,2-dicyclopropyl-6-N-[(2,6-difluorophenyl)methyl]-5-methylpyrimidine-4,6-diamine
    Show/Hide
 PubChem ID
CID: 44409976
Canonical SMILES
Cc1c(NCc2c(F)cccc2F)nc(nc1NC1CC1)C1CC1
    Show/Hide
Compound Formula C18H20F2N4
Compound Structure
Protein Name
 Protein Info 
Muscarinic acetylcholine receptor M3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Acetylcholine receptor
Uniprot ID
P20309
Gene Name
CHRM3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 63 nM
   TI
   LI
   LO
   TS