| Compound ID |
Compound Name |
Compound Formula |
|
CP0452228
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(1-ethylpiperidin-4-yl)acetamide
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|
C23H23Cl4N3O2
|
2
|
| 1 |
IC50 = 1 nM
|
|
|
| 2 |
Ki = 3 nM
|
|
|
|
CP0392090
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-ethylpiperazin-1-yl)acetamide
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|
C22H22Cl4N4O2
|
2
|
| 1 |
IC50 = 7 nM
|
|
|
| 2 |
Ki = 8 nM
|
|
|
|
CP0476871
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C21H20Cl4N4O2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0446300
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-[(3R)-3-(dimethylamino)pyrrolidin-1-yl]acetamide
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|
C22H22Cl4N4O2
|
1
|
| 1 |
IC50 = 25 nM
|
|
|
|
CP0381626
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-prop-2-enylpiperazin-1-yl)acetamide
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|
C23H22Cl4N4O2
|
2
|
| 1 |
IC50 = 38 nM
|
|
|
| 2 |
Ki = 121 nM
|
|
|
|
CP0481700
|
N-[(3S)-5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C21H21Cl3N4O2
|
2
|
| 1 |
IC50 = 47 nM
|
|
|
| 2 |
Ki = 249 nM
|
|
|
|
CP0514012
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(1-ethylpiperidin-3-yl)acetamide
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|
C23H23Cl4N3O2
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0413980
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methyl-1,4-diazepan-1-yl)acetamide
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|
C22H22Cl4N4O2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0452229
|
N-[4,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C21H21Cl3N4O2
|
2
|
| 1 |
IC50 = 72 nM
|
|
|
| 2 |
Ki = 44 nM
|
|
|
|
CP0413976
|
N-[5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-ethylpiperazin-1-yl)acetamide
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|
C22H23Cl3N4O2
|
2
|
| 1 |
IC50 = 110 nM
|
|
|
| 2 |
Ki = 202 nM
|
|
|
|
CP0523369
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-[(3S)-3-(dimethylamino)pyrrolidin-1-yl]acetamide
Show/Hide
|
C22H22Cl4N4O2
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0507783
|
N-[6-chloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C21H21Cl3N4O2
|
1
|
| 1 |
IC50 = 111 nM
|
|
|
|
CP0404930
|
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-ethylpiperazin-1-yl)acetamide
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|
C23H26Cl2N4O2
|
2
|
| 1 |
IC50 = 129 nM
|
|
|
| 2 |
Ki = 286 nM
|
|
|
|
CP0544485
|
N-[6-chloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C21H22Cl2N4O2
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0404931
|
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C22H24Cl2N4O2
|
2
|
| 1 |
IC50 = 213 nM
|
|
|
| 2 |
Ki = 392 nM
|
|
|
|
CP0392091
|
N-[6-chloro-3-(3,4-dichlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C22H23Cl3N4O2
|
2
|
| 1 |
IC50 = 220 nM
|
|
|
| 2 |
Ki > 1000 nM
|
|
|
|
CP0452230
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-[4-(dimethylamino)piperidin-1-yl]acetamide
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|
C23H24Cl4N4O2
|
1
|
| 1 |
IC50 = 239 nM
|
|
|
|
CP0513260
|
N-[5-chloro-3-(4-chlorophenyl)-6-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 = 251 nM
|
|
|
|
CP0413883
|
2-(4-methylpiperazin-1-yl)-N-[4,5,6-trichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]acetamide
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|
C21H20Cl4N4O2
|
1
|
| 1 |
IC50 = 273 nM
|
|
|
|
CP0452233
|
N-[6-chloro-3-(4-methoxyphenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C23H27ClN4O3
|
1
|
| 1 |
IC50 = 525 nM
|
|
|
|
CP0476870
|
N-[5,6-dichloro-3-(4-methoxyphenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C22H24Cl2N4O3
|
1
|
| 1 |
IC50 = 700 nM
|
|
|
|
CP0513906
|
N-[4-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 = 1160 nM
|
|
|
|
CP0452232
|
N-[6-chloro-3-(3-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 = 1180 nM
|
|
|
|
CP0544484
|
N-[5,7-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C21H21Cl3N4O2
|
1
|
| 1 |
IC50 = 1390 nM
|
|
|
|
CP0540779
|
N-[3-(4-tert-butylphenyl)-5,6-dichloro-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C25H30Cl2N4O2
|
1
|
| 1 |
IC50 = 1470 nM
|
|
|
|
CP0452746
|
N-[5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-methylpiperidin-1-yl)acetamide
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|
C22H22Cl3N3O2
|
1
|
| 1 |
IC50 = 2540 nM
|
|
|
|
CP0381625
|
N-[4,6-dichloro-3-(3,4-dichlorophenyl)-2-oxo-1H-indol-3-yl]-2-(4-ethyl-3-oxopiperazin-1-yl)acetamide
Show/Hide
|
C22H20Cl4N4O3
|
1
|
| 1 |
IC50 = 2780 nM
|
|
|
|
CP0408594
|
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-piperazin-1-ylacetamide
Show/Hide
|
C21H22Cl2N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0413978
|
N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-pyridin-4-ylpiperazin-1-yl)acetamide
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|
C26H25Cl2N5O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0446301
|
N-[6-chloro-3-(2-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
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|
C22H24Cl2N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0446327
|
N-[5,6-dichloro-3-(4-chlorophenyl)-2-oxo-1H-indol-3-yl]-2-[2-(dimethylamino)ethyl-methylamino]acetamide
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|
C21H23Cl3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0452231
|
N-[6-chloro-3-(2,4-dichlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]-2-(4-methylpiperazin-1-yl)acetamide
Show/Hide
|
C22H23Cl3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0553477
|
2-(4-benzylpiperazin-1-yl)-N-[6-chloro-3-(4-chlorophenyl)-5-methyl-2-oxo-1H-indol-3-yl]acetamide
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|
C28H28Cl2N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
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CP0860645
|
(-)-N-(5,6-dichloro-3-(4-chlorophenyl)-2-oxoindolin-3-yl)-2-(4-methylpiperazin-1-yl)acetamide
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|
C21H21Cl3N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
