| Compound ID |
Compound Name |
Compound Formula |
|
CP0382323
|
1-[4-[2-[[6-(3-aminopyrrolidin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]-3-(5-ethyl-1,2-oxazol-3-yl)urea
Show/Hide
|
C24H27N9O2S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0382169
|
1-[4-[2-[[2-methyl-6-(4-methylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]-3-phenylurea
Show/Hide
|
C26H28N8OS
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0478857
|
N-[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]-5-phenyl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C20H25ClN6S
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0538609
|
N-[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C18H22ClN7S
|
1
|
| 1 |
IC50 = 29 nM
|
|
|
|
CP0421231
|
N-[[1-[4-[[3-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]carbamoylamino]-2-(trifluoromethyl)phenyl]piperidin-4-yl]methyl]propanamide
Show/Hide
|
C34H36F3N5O5
|
2
|
| 1 |
IC50 = 33 nM
|
|
|
| 2 |
IC50 = 99 nM
|
|
|
|
CP0479773
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[3-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]prop-2-ynyl]urea
Show/Hide
|
C22H27N9O2S
|
1
|
| 1 |
IC50 = 38 nM
|
|
|
|
CP0474207
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[5-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]pyridin-2-yl]urea
Show/Hide
|
C24H28N10O2S
|
1
|
| 1 |
IC50 = 43 nM
|
|
|
|
CP0416039
|
N-(3-fluorophenyl)-N'-[3-[(E)-2-pyridin-2-ylethenyl]-1H-indazol-6-yl]propanediamide
Show/Hide
|
C23H18FN5O2
|
2
|
| 1 |
IC50 = 45 nM
|
|
|
| 2 |
IC50 = 536 nM
|
|
|
|
CP0492039
|
N-[6-[4-(2-fluoroethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C19H23ClFN7S
|
1
|
| 1 |
IC50 = 47 nM
|
|
|
|
CP0002211
|
N-[2-(diethylamino)ethyl]-5-[(Z)-(5-fluoro-2-oxo-1H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide
Show/Hide
|
C22H27FN4O2
|
3
|
| 1 |
IC50 = 48 nM
|
|
|
| 2 |
IC50 = 80 nM
|
|
|
| 3 |
IC50 = 3021 nM
|
|
|
|
CP0455160
|
N-[2-methyl-6-(2-morpholin-4-ylethoxy)pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C19H23ClN6O2S
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0492040
|
2-[4-[2-methyl-6-[(5-pyridin-4-yl-1,3-thiazol-2-yl)amino]pyrimidin-4-yl]piperazin-1-yl]ethanol;hydrochloride
Show/Hide
|
C19H24ClN7OS
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0479774
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[3-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]propyl]urea
Show/Hide
|
C23H33N9O2S
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0002778
|
4-[(4-methylpiperazin-1-yl)methyl]-N-[4-methyl-3-[(4-pyridin-3-ylpyrimidin-2-yl)amino]phenyl]benzamide
Show/Hide
|
C29H31N7O
|
5
|
| 1 |
IC50 = 53 nM
|
|
|
| 2 |
IC50 = 319 nM
|
|
|
| 3 |
IC50 = 769 nM
|
|
|
| 4 |
IC50 = 5210 nM
|
|
|
| 5 |
IC50 = 9818 nM
|
|
|
|
CP0489728
|
N-[6-[4-(dimethylamino)piperidin-1-yl]-2-methylpyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C20H26ClN7S
|
1
|
| 1 |
IC50 = 53 nM
|
|
|
|
CP0449212
|
N-[4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]benzenesulfonamide
Show/Hide
|
C26H29N7O2S2
|
1
|
| 1 |
IC50 = 54 nM
|
|
|
|
CP0142855
|
N-[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C19H24ClN7S
|
1
|
| 1 |
IC50 = 56 nM
|
|
|
|
CP0427489
|
N-[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]-5-pyridin-3-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C19H24ClN7S
|
1
|
| 1 |
IC50 = 69 nM
|
|
|
|
CP0135795
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
|
C25H29N9O2S
|
3
|
| 1 |
IC50 = 69 nM
|
|
|
| 2 |
IC50 = 82 nM
|
|
|
| 3 |
IC50 = 92 nM
|
|
|
|
CP0562854
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
|
C25H29N9O3S
|
1
|
| 1 |
IC50 = 71 nM
|
|
|
|
CP0552987
|
N-(5-ethyl-1,2-oxazol-3-yl)-4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-5-yl]-3,6-dihydro-2H-pyridine-1-carboxamide
Show/Hide
|
C25H33N9O2S
|
1
|
| 1 |
IC50 = 82 nM
|
|
|
|
CP0471979
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[4-(4-ethylpiperazin-1-yl)-6-methyl-1,3,5-triazin-2-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
|
C25H30N10O2S
|
1
|
| 1 |
IC50 = 86 nM
|
|
|
|
CP0533463
|
N-[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]-5-pyridin-3-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C18H22ClN7S
|
1
|
| 1 |
IC50 = 91 nM
|
|
|
|
CP0641297
|
N-(5-ethyl-3-isoxazolyl)-N'-[4-(2-[6-(4-ethylpiperazino)-2-methyl-4-pyrimidinyl]amino-1,3-thiazol-5-yl)phenyl]urea
Show/Hide
|
C26H31N9O2S
|
1
|
| 1 |
IC50 = 97 nM
|
|
|
|
CP0539523
|
[4-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
|
C20H24N8OS
|
1
|
| 1 |
IC50 = 98 nM
|
|
|
|
CP0426155
|
N-[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]-5-(2-methylpyridin-4-yl)-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C20H26ClN7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0470772
|
N-[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]-5-pyridin-2-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C19H24ClN7S
|
1
|
| 1 |
IC50 = 100 nM
|
|
|
|
CP0437868
|
4-[(4-methylpiperazin-1-yl)methyl]-N-(5-pyridin-3-yl-1,3-thiazol-2-yl)benzamide;hydrochloride
Show/Hide
|
C21H24ClN5OS
|
1
|
| 1 |
IC50 = 107 nM
|
|
|
|
CP0016677
|
N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide
Show/Hide
|
C35H30N4O4
|
1
|
| 1 |
IC50 = 109 nM
|
|
|
|
CP0043225
|
4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]-3-fluorophenoxy]-N-methylpyridine-2-carboxamide
Show/Hide
|
C21H15ClF4N4O3
|
1
|
| 1 |
IC50 = 116 nM
|
|
|
|
CP0543112
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-4-methyl-1,3-thiazol-5-yl]phenyl]urea
Show/Hide
|
C26H31N9O2S
|
1
|
| 1 |
IC50 = 122 nM
|
|
|
|
CP0490826
|
N-[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]-5-pyrimidin-5-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C18H23ClN8S
|
1
|
| 1 |
IC50 = 123 nM
|
|
|
|
CP0574423
|
N-[4-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]acetamide
Show/Hide
|
C21H25N7OS
|
1
|
| 1 |
IC50 = 130 nM
|
|
|
|
CP0574424
|
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]amino]-1,3-thiazol-4-yl]phenyl]urea
Show/Hide
|
C26H31N9O2S
|
1
|
| 1 |
IC50 = 950 nM
|
|
|
|
CP0139001
|
N-(4-fluorophenyl)-1-methyl-3-[[methyl-[2-(4-phenylphenyl)ethyl]amino]methyl]indole-5-carboxamide
Show/Hide
|
C32H30FN3O
|
1
|
| 1 |
IC50 = 11000 nM
|
|
|
|
CP0490827
|
N-[6-(4-ethylpiperazin-1-yl)-2-methylpyrimidin-4-yl]-4-pyridin-3-yl-1,3-thiazol-2-amine;hydrochloride
Show/Hide
|
C19H24ClN7S
|
1
|
| 1 |
IC50 > 1000 nM
|
|
|
