Brief Information of the Compound and Protein
Compound Name
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
    Show/Hide
PubChem ID
CID: 130313548
Canonical SMILES
CCc1cc(NC(=O)Nc2ccc(cc2)-c2cnc(Nc3cc(ncn3)N3CCN(CCO)CC3)s2)no1
    Show/Hide
Compound Formula C25H29N9O3S
Compound Structure
Protein Name
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 71 nM
   TI
   LI
   LO
   TS