Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(5-ethyl-1,2-oxazol-3-yl)-3-[4-[2-[[6-(4-ethylpiperazin-1-yl)pyrimidin-4-yl]amino]-1,3-thiazol-5-yl]phenyl]urea
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 PubChem ID
CID: 130313537
Canonical SMILES
CCN1CCN(CC1)c1cc(Nc2ncc(s2)-c2ccc(NC(=O)Nc3cc(CC)on3)cc2)ncn1
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Compound Formula C25H29N9O2S
Compound Structure
Protein Name
 Protein Info 
Mast/stem cell growth factor receptor Kit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P10721
Gene Name
KIT
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 69 nM
   TI
   LI
   LO
   TS
2
IC50 = 82 nM
   TI
   LI
   LO
   TS
3
IC50 = 92 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.02 nM
2 IC50 = 0.12 nM
3 IC50 = 0.18 nM
4 IC50 = 0.67 nM
5 IC50 = 0.81 nM
6 IC50 = 0.89 nM
7 IC50 = 0.98 nM
8 IC50 = 1.37 nM
9 IC50 = 1.66 nM
10 IC50 = 4.14 nM
11 IC50 = 8.56 nM
12 IC50 = 9.27 nM
13 IC50 = 102 nM