General Information of the Compound
| Compound ID |
CP0455160
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| Compound Name |
N-[2-methyl-6-(2-morpholin-4-ylethoxy)pyrimidin-4-yl]-5-pyridin-4-yl-1,3-thiazol-2-amine;hydrochloride
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| Structure |
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| Formula |
C19H23ClN6O2S
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| Molecular Weight |
434.953
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| Canonical SMILES |
Cl.Cc1nc(Nc2ncc(s2)-c2ccncc2)cc(OCCN2CCOCC2)n1
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| InChI |
InChI=1S/C19H22N6O2S.ClH/c1-14-22-17(12-18(23-14)27-11-8-25-6-9-26-10-7-25)24-19-21-13-16(28-19)15-2-4-20-5-3-15;/h2-5,12-13H,6-11H2,1H3,(H,21,22,23,24);1H
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| InChIKey |
CZWUFIJAJZAZOT-UHFFFAOYSA-N
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00888, Mast/stem cell growth factor receptor Kit
Protein ID: PT01204, Receptor-type tyrosine-protein kinase FLT3