General Information of the Compound
Compound ID
CP0314294
Compound Name
(9-ethylcarbazol-3-yl)-(5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)amine
    Show/Hide
Structure
Formula
C20H18N6
Molecular Weight
342.406
Canonical SMILES
CCn1c2ccccc2c2cc(Nc3cc(C)nc4ncnn34)ccc12
    Show/Hide
InChI
InChI=1S/C20H18N6/c1-3-25-17-7-5-4-6-15(17)16-11-14(8-9-18(16)25)24-19-10-13(2)23-20-21-12-22-26(19)20/h4-12,24H,3H2,1-2H3
    Show/Hide
InChIKey
OLGRAIQONDDWCX-UHFFFAOYSA-N
Physicochemical Property
logP
4.30412
Rotatable Bonds
3
Heavy Atom Count
26
Polar Areas
60.04
Hydrogen Bond Donor Count
1
Hydrogen Bond Acceptor Count
6
Complexity
26

"RO5" indicates the cutoff set by lipinski's rule of five:

(1) Molecular weight less than 500 Dalton;

(2) xlogp less than 5;

(3) No more than 5 hbonddonor (Hydrogen Bond Donor Count);

(4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count);

(5) No more than 10 rotbonds (Rotatable Bond Count).

    Show/Hide
Click to Show/Hide the External Link(s) of This Compound
PubChem ID
CID: 5307716
ChEMBL ID
CHEMBL1432507
Map of Molecular Bioactivity Related to the Compound
Map of Molecular Bioactivity Related to the Compound

Compound
Cell Line
Protein

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Compound
Protein ID: PT02805, CREB-binding protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Potency = 15848.9 nM
   TI
   LI
   LO
   TS
Protein ID: PT06109, Geminin
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000015 SW480 Homo sapiens (Human)  1
1
Potency ~ 580.5 nM
   TI
   LI
   LO
   TS
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000156 HT-1080 Homo sapiens (Human)  1
1
Potency ~ 580.5 nM
   TI
   LI
   LO
   TS