General Information of the Compound
| Compound ID |
CP0234575
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| Compound Name |
US9199927, camostat
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| Synonyms |
0FD207WKDU
4-(2-(2-(Dimethylamino)-2-oxoethoxy)-2-oxoethyl)phenyl 4-guanidinobenzoate
59721-28-7
C20H22N4O5
CCRIS 7219
CHEMBL85164
Camostat
Camostat (INN)
Camostat [INN]
Camostatum
Camostatum [INN-Latin]
Dimethylcarbamoylmethyl 4-(4-guqnidinobenzoyloxy)phenylacetat
FOY 305
FOY-305
Foipan
UNII-0FD207WKDU
[4-[2-[2-(dimethylamino)-2-oxoethoxy]-2-oxoethyl]phenyl] 4-(diaminomethylideneamino)benzoate
camostate
camostate-mesilate
foypan
p-Guanidinobenzoic acid, ester with (p-hydroxyphenyl)acetic acid, ester with N
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| Structure |
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| Formula |
C20H22N4O5
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| Molecular Weight |
398.419
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| Canonical SMILES |
CN(C)C(=O)COC(=O)Cc1ccc(OC(=O)c2ccc(NC(N)=N)cc2)cc1
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| InChI |
InChI=1S/C20H22N4O5/c1-24(2)17(25)12-28-18(26)11-13-3-9-16(10-4-13)29-19(27)14-5-7-15(8-6-14)23-20(21)22/h3-10H,11-12H2,1-2H3,(H4,21,22,23)
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| InChIKey |
XASIMHXSUQUHLV-UHFFFAOYSA-N
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| CAS |
59721-28-7
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT03019, Hepatocyte growth factor activator
Protein ID: PT02186, Liver carboxylesterase 1
Protein ID: PT05367, Multidrug and toxin extrusion protein 1
Protein ID: PT05330, Multidrug and toxin extrusion protein 2
Protein ID: PT03005, Serine protease hepsin
Protein ID: PT04591, Solute carrier family 22 member 2
Clinical Information about the Compound