General Information of the Compound
| Compound ID |
CP0084343
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| Compound Name |
N,N-dimethyl-3-(10-phenothiazinyl)-1-propanamine;hydrochloride
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| Synonyms |
10-(3-(Dimethylamino)propyl)phenothiazine
10-[3-(Dimethylamino)propyl]phenothiazine
10H-Phenothiazine-10-propanamine, N,N-dimethyl-(9CI)
10H-Phenothiazine-10-propanamine, N,N-dimethyl-, monohydrochloride
A 145
Ampazine
Berophen
Combelen [veterinary]
Combelen [veterinary] (TN)
Dimethyl(3-phenothiazin-10-ylpropyl)amine
Esparin
Liranol
N,N-dimethyl-3-(10H-phenothiazin-10-yl)propan-1-amine
N,N-dimethyl-3-phenothiazin-10-ylpropan-1-amine
N-(3-Dimethylaminopropyl)phenothiazine
N-Dimethylamino-1-methylethyl thiodiphenylamine
Neo-Hibernex
Prazin
Prazine
Promazin
Promazina
Promazina [INN-Spanish]
Promazina [Italian]
Promazine
Promazine (INN)
Promazine [INN:BAN]
Promazinum
Promazinum [INN-Latin]
Promwill
Propazinum
Protactyl
RP 3276
Romtiazin
Sinophenin
Sparine (TN)
Tomil
Verophen
WY 1094
Wy-1094
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| Structure |
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| Formula |
C17H20N2S
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| Molecular Weight |
284.428
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| Canonical SMILES |
CN(C)CCCN1c2ccccc2Sc2ccccc12
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| InChI |
InChI=1S/C17H20N2S/c1-18(2)12-7-13-19-14-8-3-5-10-16(14)20-17-11-6-4-9-15(17)19/h3-6,8-11H,7,12-13H2,1-2H3
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| InChIKey |
ZGUGWUXLJSTTMA-UHFFFAOYSA-N
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| CAS |
58-40-2
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00817, Cytochrome P450 2D6
Protein ID: PT01206, Histamine H1 receptor
Protein ID: PT02997, Isocitrate dehydrogenase [NADP] cytoplasmic
Protein ID: PT02591, Major prion protein
Protein ID: PT01065, Serine/threonine-protein kinase mTOR
Protein ID: PT03795, Solute carrier family 22 member 1
Clinical Information about the Compound