General Information of the Compound
| Compound ID |
CP0075091
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| Compound Name |
indolo[2,1-b]quinazoline-6,12-dione
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| Synonyms |
GNF-PF-2691
couroupitine a
tryptanthrin
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| Structure |
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| Formula |
C15H8N2O2
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| Molecular Weight |
248.241
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| Canonical SMILES |
O=C1c2ccccc2-n2c1nc1ccccc1c2=O
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| InChI |
InChI=1S/C15H8N2O2/c18-13-10-6-2-4-8-12(10)17-14(13)16-11-7-3-1-5-9(11)15(17)19/h1-8H
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| InChIKey |
VQQVWGVXDIPORV-UHFFFAOYSA-N
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| CAS |
13220-57-0
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT01390, BDNF/NT-3 growth factors receptor
Protein ID: PT06109, Geminin
Protein ID: PT00934, High affinity nerve growth factor receptor
Protein ID: PT03341, Indoleamine 2,3-dioxygenase 2
Protein ID: PT00863, Mitogen-activated protein kinase 8
Protein ID: PT02896, Tryptophan 2,3-dioxygenase
Clinical Information about the Compound