Brief Information of the Compound and Protein
Compound Name
 Compound Info 
indolo[2,1-b]quinazoline-6,12-dione
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 PubChem ID
CID: 73549
SID: 15196648
Canonical SMILES
O=C1c2ccccc2-n2c1nc1ccccc1c2=O
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Compound Formula C15H8N2O2
Compound Structure
Protein Name
 Protein Info 
Tryptophan 2,3-dioxygenase
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P48775
Gene Name
TDO2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 140 nM
   TI
   LI
   LO
   TS
CL000102 U-87MG ATCC
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 194 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 900 nM