General Information of the Compound
| Compound ID |
CP0026502
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| Compound Name |
(2R)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
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| Synonyms |
(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoic acid
3,3',5-Triiodo-L-thyronine
3,3',5-Triiodothyronine
3,3'5-Triiodo-L-thyronine
3,5,3'-Tri-iodo-L-thyronine
3,5,3'-Triiodo-L-thyronine
3,5,3'-triiodothyronine
3,5,3'TRIIODOTHYRONINE
4-(3-Iodo-4-hydroxyphenoxy)-3,5-diiodophenylalanine
4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenylalanine
4-(4-hydroxy-3-iodophenoxy)-3,5-diiodo-L-phenylalanine
6893-02-3
6893/2/3
Cytomel (TN)
Euthroid-05
Euthroid-1
Euthroid-2
Euthroid-3
L-3,3',5-TriioDOThyronine
L-3,5,3'-Triiodothyronine
L-3-(4-(4-Hydroxy-3-iodophenoxy)-3,5-diiodophenyl)alanine
L-Liothyronine
L-T3
L-Tyrosine, O-(4-hydroxy-3-iodophenyl)-3,5-diiodo-(9CI)
Li
Liothyronin
Liothyronine
Liothyronine (INN)
Liothyronine I 131
Liothyronine I 131 [USAN]
Liothyronine [INN:BAN]
Liothyroninum
Liothyroninum[INN-Latin]
Liotironina
Liotironina [INN-Spanish]
Lyothyronine
O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine
Rathyronine
T3
T3 (Hormone)
T3 (Triiodothyronine)
T3 (VAN)
T3 (amino acid)
T3 liothyronine
THYROID HORMONE
TRIIODOTHYRONINE (T3 OR LIOTHYRONINE, ACTIVE) (6-11%)
Tertroxin (TN)
Thyrolar-025
Thyrolar-05
Thyrolar-1
Thyrolar-2
Thyrolar-3
Thyronine, 3,3',5-triiodo-, L-(6CI)
Tresitope
Tri-Thyrotope
Triiodo-L-thyronine
Triiodothyronine
Triiodothyronine (T3)
Triomet-131
Triothyrone
liothyronine
triiodothyronine
triothyrone
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| Structure |
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| Formula |
C15H12I3NO4
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| Molecular Weight |
650.976
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| Canonical SMILES |
N[C@@H](Cc1cc(I)c(Oc2ccc(O)c(I)c2)c(I)c1)C(O)=O
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| InChI |
InChI=1S/C15H12I3NO4/c16-9-6-8(1-2-13(9)20)23-14-10(17)3-7(4-11(14)18)5-12(19)15(21)22/h1-4,6,12,20H,5,19H2,(H,21,22)/t12-/m0/s1
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| InChIKey |
AUYYCJSJGJYCDS-LBPRGKRZSA-N
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| CAS |
57164-27-9
7013-53-8
20196-64-9
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| Physicochemical Property |
"RO5" indicates the cutoff set by lipinski's rule of five: (1) Molecular weight less than 500 Dalton; (2) xlogp less than 5; (3) No more than 5 hbonddonor (Hydrogen Bond Donor Count); (4) No more than 10 hbondacc (Hydrogen Bond Acceptor Count); (5) No more than 10 rotbonds (Rotatable Bond Count). Show/Hide
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Map of Molecular Bioactivity Related to the Compound
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Map of Molecular Bioactivity Related to the Compound Compound Cell Line Protein Bioactivity Value: <= 0.1 μM > 0.1 μM and <= 10 μM > 10 μM Imprecise Activity |
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Table of Molecular Bioactivities Related to the Compound
Protein ID: PT00894, Androgen receptor
Protein ID: PT00915, Peroxisome proliferator-activated receptor gamma
Protein ID: PT00822, Prothrombin
Protein ID: PT06163, Solute carrier organic anion transporter family member 1A3
Protein ID: PT06835, Solute carrier organic anion transporter family member 1C1
Protein ID: PT06838, Solute carrier organic anion transporter family member 4C1
Protein ID: PT06337, Solute carrier organic anion transporter family member 4C1
Protein ID: PT01591, Thyroid hormone receptor alpha
Cell-based Assay
Protein ID: PT01018, Thyroid hormone receptor beta
Cell-based Assay
Clinical Information about the Compound
Drug 1 ( Liothyronine )
| Drug Name | Liothyronine | ||
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| Company | King Pharmaceuticals, Inc | ||
| Indication | |||
| Target(s) |
Thyroid hormone receptor alpha (THRA)
Antagonist
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