General Information of the Cell Line
Cell Line ID
CL000155
Cell Line Name
HT-144
Synonyms
HT 144
HT144
HT144-mel
HT144mel
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0318
Tissue Information
Hypodermis
Disease
Melanoma (NCIt: C3224)
Map of Molecular Bioactivity Related to the Cell Line
Map of Molecular Bioactivity Related to the Cell Line

Cell Line
Protein
Compound

Bioactivity Value:

<= 0.1 μM
> 0.1 μM and <= 10 μM
> 10 μM
Imprecise Activity
Table of Molecular Bioactivities Related to the Cell Line
Protein ID: PT00955, DNA-dependent protein kinase catalytic subunit
 Protein Info 
Compound ID Compound Name Compound Formula
CP0014320
 Compound Info 
CHEMBL4871998
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C21H17F2N5
  1
1
IC50 = 44 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0014706
 Compound Info 
8-[5-(difluoromethyl)pyridin-3-yl]-1-(3,6-dihydro-2H-pyran-4-yl)-[1,2,4]triazolo[4,3-a]quinoxaline
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C20H15F2N5O
  1
1
IC50 = 47 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0013686
 Compound Info 
8-[5-(difluoromethyl)pyridin-3-yl]-1-(4-methoxycyclohexyl)-[1,2,4]triazolo[4,3-a]quinoxaline
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C22H21F2N5O
  1
1
IC50 = 53 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0014718
 Compound Info 
1-(cyclohepten-1-yl)-8-[5-(difluoromethyl)pyridin-3-yl]-[1,2,4]triazolo[4,3-a]quinoxaline
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C22H19F2N5
  1
1
IC50 = 60 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0013685
 Compound Info 
8-[5-(difluoromethyl)pyridin-3-yl]-1-(2,3,6,7-tetrahydrooxepin-4-yl)-[1,2,4]triazolo[4,3-a]quinoxaline
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C21H17F2N5O
  1
1
IC50 = 69 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0003520
 Compound Info 
8-[5-(difluoromethyl)pyridin-3-yl]-1-(4-methoxycyclohexyl)-[1,2,4]triazolo[4,3-a]quinoxaline
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C22H21F2N5O
  1
1
IC50 = 92 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0005823
 Compound Info 
CHEMBL4873263
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C20H15F2N5O
  1
1
IC50 = 98 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0014710
 Compound Info 
1-(cyclohexen-1-yl)-8-[5-(difluoromethyl)pyridin-3-yl]-[1,2,4]triazolo[4,3-a]quinoxaline
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C21H17F2N5
  1
1
IC50 = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0014701
 Compound Info 
8-[5-(difluoromethyl)pyridin-3-yl]-1-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]quinoxaline
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C20H17F2N5O
  1
1
IC50 = 1130 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0113988
 Compound Info 
CEP-32496
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 C24H22F3N5O5  1
1
EC50 = 228 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Hypodermis)
Cell Line Name Organism Disease
MDA-MB-435
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
MDA435/LCC6MDR1
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
M14
 Cell Line Info 
Homo sapiens (Human) Amelanotic melanoma
ChaGo-K-1
 Cell Line Info 
Homo sapiens (Human) Bronchogenic carcinoma
NCI-H125
 Cell Line Info 
Homo sapiens (Human) Lung adenosquamous carcinoma