Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-[5-(difluoromethyl)pyridin-3-yl]-1-(4-methoxycyclohexyl)-[1,2,4]triazolo[4,3-a]quinoxaline
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Canonical SMILES
CO[C@H]1CC[C@H](CC1)c1nnc2cnc3ccc(cc3n12)-c1cncc(c1)C(F)F
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Compound Formula C22H21F2N5O
Compound Structure
Protein Name
 Protein Info 
DNA-dependent protein kinase catalytic subunit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
P78527
Gene Name
PRKDC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000155 HT-144
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 53 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 39 nM