General Information of the Cell Line
Cell Line ID
CL000637
Cell Line Name
M14
Synonyms
M14-MEL
UCLA-SO-M14
UCLA SO M14
UCLA-SO-14
UCLASO-M14
Melanoma 14
M-14
Category
Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_1395
Tissue Information
Hypodermis
Disease
Amelanotic melanoma (NCIt: C3802)
Table of Molecular Bioactivities Related to the Cell Line
Cell Viability or Cytotoxicity Assay
Compound ID Compound Name Compound Formula
CP0006369
6-[3-[4-[1-(5-cyanopentyl)indol-3-yl]-1-hydroxy-2,5-dioxopyrrol-3-yl]indol-1-yl]hexanenitrile
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C32H31N5O3  1
1
GI50 = 4420 nM
   TI
   LI
   LO
   TS
CP0082019
(2R)-2-amino-3-[(triphenylmethyl)sulfanyl]propanoic acid
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C22H21NO2S  1
1
GI50 = 398 nM
   TI
   LI
   LO
   TS
CP0148456
(2R)-2-amino-3-[(4-methoxyphenyl)-diphenylmethyl]sulfanylpropan-1-ol
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C23H25NO2S  1
1
GI50 = 20 nM
   TI
   LI
   LO
   TS
CP0370065
5-(4-chlorophenyl)-2-(4-methoxyphenyl)-[1,3]thiazolo[3,2-b][1,2,4]triazole
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C17H12ClN3OS  1
1
LC50 > 50000 nM
   TI
   LI
   LO
   TS
CP0383276
N-(4-methoxyphenyl)-N,2,6-trimethylfuro[2,3-d]pyrimidin-4-amine
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C16H17N3O2  1
1
GI50 = 23.3 nM
   TI
   LI
   LO
   TS
CP0897293
1-(7-Benzyl-2-methyl-5H-pyrrolo[3,2-d]pyrimidin-4-yl)-6-methoxy-1,2,3,4-tetrahydroquinoline hydrochloride
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C24H25ClN4O  1
1
GI50 = 252 nM
   TI
   LI
   LO
   TS
CP0906523
7-Benzyl-N-(4-methoxyphenyl)-N,2,5-trimethyl-5H-pyrrolo[3,2-d]pyrimidin-4-amine hydrochloride
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C23H25ClN4O  1
1
GI50 = 29.5 nM
   TI
   LI
   LO
   TS
Protein family and CMB statistics Related to the Cell Line
Cell Lines Derived from the same Tissue Source (Hypodermis)
Cell Line Name Organism Disease
MDA-MB-435 Homo sapiens (Human) Amelanotic melanoma
MDA435/LCC6MDR1 Homo sapiens (Human) Amelanotic melanoma
ChaGo-K-1 Homo sapiens (Human) Bronchogenic carcinoma
NCI-H125 Homo sapiens (Human) Lung adenosquamous carcinoma
HT-144 Homo sapiens (Human) Melanoma