Brief Information of the Compound and Protein
Compound Name
8-[5-(difluoromethyl)pyridin-3-yl]-1-(oxan-4-yl)-[1,2,4]triazolo[4,3-a]quinoxaline
    Show/Hide
Canonical SMILES
FC(F)c1cncc(c1)-c1ccc2ncc3nnc(C4CCOCC4)n3c2c1
    Show/Hide
Compound Formula C20H17F2N5O
Compound Structure
Protein Name
DNA-dependent protein kinase catalytic subunit
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Atypical protein kinase group
>
Atypical protein kinase PIKK family
Uniprot ID
P78527
Gene Name
PRKDC
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000155 HT-144 Homo sapiens (Human)  1
1
IC50 = 1130 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 105 nM