| Compound ID |
Compound Name |
Compound Formula |
|
CP0210909
|
(2S)-1,1,1-trifluoro-2-[4-(1H-pyrazol-1-yl)phenyl]-3-(4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1H-imidazol-2-yl)propan-2-ol
Show/Hide
|
C20H18F6N4O
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0465653
|
2-[4-(1H-pyrazol-1-yl)phenyl]-1-(4-{[1-(trifluoromethyl)cyclopropyl]methyl}-1H-imidazol-2-yl)propan-2-ol
Show/Hide
|
C20H21F3N4O
|
1
|
| 1 |
EC50 = 14 nM
|
|
|
|
CP0436009
|
N-methyl-1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
Show/Hide
|
C26H22F6N4O4S
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0313839
|
1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(1H-pyrazol-1-yl)phenyl]propan-2-ol
Show/Hide
|
C20H26N4O
|
1
|
| 1 |
EC50 = 16 nM
|
|
|
|
CP0410792
|
1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutane-1-carboxamide
Show/Hide
|
C25H20F6N4O4S
|
1
|
| 1 |
EC50 = 21 nM
|
|
|
|
CP0365995
|
4'-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
EC50 = 25 nM
|
|
|
|
CP0504219
|
2-methyl-2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propanamide
Show/Hide
|
C24H20F6N4O4S
|
1
|
| 1 |
EC50 = 26 nM
|
|
|
|
CP0401461
|
4'-(2-(5-(3,3-dimethylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
EC50 = 39 nM
|
|
|
|
CP0191374
|
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazole
Show/Hide
|
C25H22F3N5O3S
|
1
|
| 1 |
EC50 = 40 nM
|
|
|
|
CP0384386
|
4'-(2-(5-(cyclohexylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H28N2O2
|
1
|
| 1 |
EC50 = 41 nM
|
|
|
|
CP0315939
|
6-(4-tert-butylphenyl)sulfonyl-7-pyridin-3-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C28H25F3N4O2S
|
1
|
| 1 |
EC50 = 42 nM
|
|
|
|
CP0225161
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)pyridine
Show/Hide
|
C22H27N3
|
1
|
| 1 |
EC50 = 47 nM
|
|
|
|
CP0110516
|
(1S)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
Show/Hide
|
C27H26F3N5O4S
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0179883
|
2-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C28H28F3N5O4S
|
1
|
| 1 |
EC50 = 52 nM
|
|
|
|
CP0315938
|
[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]methanol
Show/Hide
|
C26H24F3N5O4S
|
1
|
| 1 |
EC50 = 56 nM
|
|
|
|
CP0315941
|
6-(4-tert-butylphenyl)sulfonyl-7-(1-methylpyrazol-4-yl)-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C27H26F3N5O2S
|
1
|
| 1 |
EC50 = 63 nM
|
|
|
|
CP0385699
|
2-[3-[2-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]propan-2-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C28H25F6N5O5S
|
1
|
| 1 |
EC50 = 64 nM
|
|
|
|
CP0401480
|
2-(4-(2-(4-(2,2-dimethylbutyl)-1H-imidazol-2-yl)ethyl)phenyl)-5-fluoropyridine
Show/Hide
|
C22H26FN3
|
1
|
| 1 |
EC50 = 66 nM
|
|
|
|
CP0210908
|
1-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-2-[4-(5-fluoropyridin-2-yl)phenyl]propan-2-ol
Show/Hide
|
C22H26FN3O
|
1
|
| 1 |
EC50 = 67 nM
|
|
|
|
CP0315940
|
(1R)-1-[3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]ethanol
Show/Hide
|
C27H26F3N5O4S
|
1
|
| 1 |
EC50 = 69 nM
|
|
|
|
CP0256765
|
2-[3-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C25H19F6N5O5S
|
1
|
| 1 |
EC50 = 73 nM
|
|
|
|
CP0440144
|
4'-(2-(5-(2-ethyl-2-methylbutyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O2
|
1
|
| 1 |
EC50 = 76 nM
|
|
|
|
CP0192143
|
3-[6-(4-tert-butylphenyl)sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]-4H-1,2,4-oxadiazol-5-one
Show/Hide
|
C25H22F3N5O4S
|
1
|
| 1 |
EC50 = 77 nM
|
|
|
|
CP0385700
|
2-[3-[1-[6-[4-(trifluoromethoxy)phenyl]sulfonyl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepin-7-yl]cyclobutyl]-1,2,4-oxadiazol-5-yl]propan-2-ol
Show/Hide
|
C29H25F6N5O5S
|
1
|
| 1 |
EC50 = 82 nM
|
|
|
|
CP0373921
|
4'-(2-(5-(2,3-difluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H20F2N2O2
|
1
|
| 1 |
EC50 = 87 nM
|
|
|
|
CP0373978
|
4'-(2-(5-(cycloheptylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
EC50 = 88 nM
|
|
|
|
CP0401431
|
4'-(2-(5-neopentyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
EC50 = 106 nM
|
|
|
|
CP0315773
|
6-(4-tert-butylphenyl)sulfonyl-7-piperidin-4-yl-2-(trifluoromethyl)-5,11-dihydropyrido[3,2-c][1,5]benzodiazepine
Show/Hide
|
C28H31F3N4O2S
|
1
|
| 1 |
EC50 = 114 nM
|
|
|
|
CP0401437
|
4'-(2-(5-isopentyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
EC50 = 119 nM
|
|
|
|
CP0440147
|
4'-(2-(5-(2-methylbenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
EC50 = 127 nM
|
|
|
|
CP0402259
|
4'-(2-(5-(cyclopentylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H26N2O2
|
1
|
| 1 |
EC50 = 133 nM
|
|
|
|
CP0401439
|
4'-(2-(5-(3-fluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21FN2O2
|
1
|
| 1 |
EC50 = 159 nM
|
|
|
|
CP0440150
|
4'-(2-(5-(2-fluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21FN2O2
|
1
|
| 1 |
EC50 = 177 nM
|
|
|
|
CP0373976
|
4'-(2-(5-benzyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H22N2O2
|
1
|
| 1 |
EC50 = 205 nM
|
|
|
|
CP0298320
|
2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(5-fluoropyridin-2-yl)phenyl]propan-2-ol
Show/Hide
|
C22H26FN3O
|
1
|
| 1 |
EC50 = 220 nM
|
|
|
|
CP0373715
|
4'-(2-(5-(2-chlorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21ClN2O2
|
1
|
| 1 |
EC50 = 292 nM
|
|
|
|
CP0373918
|
4'-(2-(5-((tetrahydro-2H-pyran-4-yl)methyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H26N2O3
|
1
|
| 1 |
EC50 = 338 nM
|
|
|
|
CP0401424
|
4'-(2-(5-cyclohexyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H26N2O2
|
1
|
| 1 |
EC50 = 375 nM
|
|
|
|
CP0373809
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-2,2-dimethylbutanamide
Show/Hide
|
C27H36N6O
|
1
|
| 1 |
EC50 = 543 nM
|
|
|
|
CP0447838
|
4'-(2-(5-(cyclobutylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C23H24N2O2
|
1
|
| 1 |
EC50 = 588 nM
|
|
|
|
CP0447839
|
4'-(2-(5-(2-cyclohexylethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H30N2O2
|
1
|
| 1 |
EC50 = 642 nM
|
|
|
|
CP0407113
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)cyclopentanecarboxamide
Show/Hide
|
C27H34N6O
|
1
|
| 1 |
EC50 = 704 nM
|
|
|
|
CP0401436
|
4'-(2-(5-(3-cyanobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H21N3O2
|
1
|
| 1 |
EC50 = 812 nM
|
|
|
|
CP0440149
|
4'-(2-(5-(3-chlorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21ClN2O2
|
1
|
| 1 |
EC50 = 825 nM
|
|
|
|
CP0401440
|
4'-(2-(5-(cyclopropylmethyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H22N2O2
|
1
|
| 1 |
EC50 = 1004 nM
|
|
|
|
CP0407688
|
4'-(2-(5-butyl-1H-imidazol-2-yl)pentyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O2
|
1
|
| 1 |
EC50 = 1183 nM
|
|
|
|
CP0430795
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-3,3-dimethylbutanamide
Show/Hide
|
C27H36N6O
|
1
|
| 1 |
EC50 = 1234 nM
|
|
|
|
CP0401434
|
4'-(2-(5-phenethyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
EC50 = 1323 nM
|
|
|
|
CP0467436
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-2,2-dimethylpropanamide
Show/Hide
|
C26H34N6O
|
1
|
| 1 |
EC50 = 1542 nM
|
|
|
|
CP0401426
|
4'-(2-(5-(4-fluorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21FN2O2
|
1
|
| 1 |
EC50 = 1601 nM
|
|
|
|
CP0384384
|
4'-(2-(5-(2-methoxybenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
EC50 = 1724 nM
|
|
|
|
CP0373910
|
4'-(2-(5-butyl-1H-imidazol-2-yl)-5-hydroxypentyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O3
|
2
|
| 1 |
EC50 = 1897 nM
|
|
|
| 2 |
EC50 = 1900 nM
|
|
|
|
CP0401438
|
4'-(2-(5-(4-chlorobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H21ClN2O2
|
1
|
| 1 |
EC50 = 2288 nM
|
|
|
|
CP0440145
|
4'-(2-(5-butyl-1H-imidazol-2-yl)hexyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H32N2O2
|
1
|
| 1 |
EC50 = 2656 nM
|
|
|
|
CP0373923
|
4'-(2-(5-(4-methylbenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
EC50 = 2663 nM
|
|
|
|
CP0513491
|
4'-(2-(5-butyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 = 2707 nM
|
|
|
|
CP0402260
|
4'-(2-(5-butyl-1H-imidazol-2-yl)butyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H28N2O2
|
1
|
| 1 |
EC50 = 2722 nM
|
|
|
|
CP0402261
|
4'-(2-(5-butyl-1H-imidazol-2-yl)propyl)biphenyl-2-carboxylic acid
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
EC50 = 2760 nM
|
|
|
|
CP0401371
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)acetamide
Show/Hide
|
C23H28N6O
|
1
|
| 1 |
EC50 = 3164 nM
|
|
|
|
CP0373811
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)propanamide
Show/Hide
|
C24H30N6O
|
1
|
| 1 |
EC50 = 3474 nM
|
|
|
|
CP0401435
|
4'-(2-(5-(3-methoxybenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
EC50 = 4124 nM
|
|
|
|
CP0406802
|
7-benzyl-N-neopentyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C26H36N6
|
1
|
| 1 |
EC50 = 4149 nM
|
|
|
|
CP0402258
|
4'-(2-(5-(3-methylbenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O2
|
1
|
| 1 |
EC50 = 4307 nM
|
|
|
|
CP0401462
|
4'-(2-(5-tert-butyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H24N2O2
|
1
|
| 1 |
EC50 = 4334 nM
|
|
|
|
CP0850185
|
4'-(2-(5-butyl-1H-imidazol-2-yl)vinyl)biphenyl-2-carboxylic acid
Show/Hide
|
C22H22N2O2
|
1
|
| 1 |
EC50 = 4376 nM
|
|
|
|
CP0390998
|
7-Benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine
Show/Hide
|
C21H26N6
|
1
|
| 1 |
EC50 = 4525 nM
|
|
|
|
CP0440148
|
4'-(2-(5-butyl-1H-imidazol-2-yl)-3-methylbutyl)biphenyl-2-carboxylic acid
Show/Hide
|
C25H30N2O2
|
1
|
| 1 |
EC50 = 4618 nM
|
|
|
|
CP0373810
|
N-(7-benzyl-5-piperidin-1-yl-3,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-yl)-2-methylpropanamide
Show/Hide
|
C25H32N6O
|
1
|
| 1 |
EC50 = 4763 nM
|
|
|
|
CP0373913
|
4'-(2-(5-phenyl-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C24H20N2O2
|
1
|
| 1 |
EC50 = 4949 nM
|
|
|
|
CP0407687
|
4'-(2-(5-(4-methoxybenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H24N2O3
|
1
|
| 1 |
EC50 = 5360 nM
|
|
|
|
CP0373979
|
4'-(2-(5-(2-cyanobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H21N3O2
|
1
|
| 1 |
EC50 = 5479 nM
|
|
|
|
CP0391006
|
7-(2-chlorobenzyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C21H25ClN6
|
1
|
| 1 |
EC50 = 5567 nM
|
|
|
|
CP0401433
|
4'-(3-(5-butyl-1H-imidazol-2-yl)propyl)biphenyl-2-carboxylic acid
Show/Hide
|
C23H26N2O2
|
1
|
| 1 |
EC50 = 5598 nM
|
|
|
|
CP0470281
|
4'-(2-(5-(4-cyanobenzyl)-1H-imidazol-2-yl)ethyl)biphenyl-2-carboxylic acid
Show/Hide
|
C26H21N3O2
|
1
|
| 1 |
EC50 = 5887 nM
|
|
|
|
CP0373052
|
5-(Piperidin-1-yl)-7-(pyridin-2-ylmethyl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
Show/Hide
|
C20H25N7
|
1
|
| 1 |
EC50 = 6779 nM
|
|
|
|
CP0384385
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4'-((5-butyl-1H-imidazol-2-yl)methyl)biphenyl-2-carboxylic acid
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C21H22N2O2
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1
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| 1 |
EC50 > 10000 nM
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CP0373048
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7-benzyl-5-(4-methylpiperazin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C21H27N7
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1
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| 1 |
EC50 = 10000 nM
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CP0373049
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7-benzyl-3-methyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C22H28N6
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1
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| 1 |
EC50 = 10000 nM
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CP0373050
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5-(piperidin-1-yl)-7-(3-(trifluoromethyl)benzyl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C22H25F3N6
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1
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| 1 |
EC50 = 10000 nM
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CP0373051
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7-[(4-fluorophenyl)methyl]-5-piperidin-1-yl-2,6,8,9-tetrahydropyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C21H25FN6
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1
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| 1 |
EC50 = 10000 nM
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CP0373053
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7-benzyl-N5-phenyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
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C22H22N6
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1
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| 1 |
EC50 = 10000 nM
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CP0373054
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7-benzyl-5-(pyrrolidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C20H24N6
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1
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| 1 |
EC50 = 10000 nM
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CP0373056
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7-(4-methoxybenzyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C22H28N6O
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1
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| 1 |
EC50 = 10000 nM
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CP0373057
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7-benzyl-N5-cyclohexyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
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C22H28N6
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1
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| 1 |
EC50 = 10000 nM
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CP0373534
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7-benzyl-5-(4-methylpiperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C22H28N6
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1
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| 1 |
EC50 = 10000 nM
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CP0390999
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7-phenethyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C22H28N6
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1
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| 1 |
EC50 = 10000 nM
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CP0391000
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7-(cyclohexylmethyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C21H32N6
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1
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| 1 |
EC50 = 10000 nM
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CP0391001
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7-benzyl-N5-isopropyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
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C19H24N6
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1
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| 1 |
EC50 = 10000 nM
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CP0400203
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7-benzyl-5-(4-fluoropiperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C21H25FN6
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1
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| 1 |
EC50 = 10000 nM
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CP0401372
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7-isobutyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C18H28N6
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1
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| 1 |
EC50 = 10000 nM
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CP0401375
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7-benzyl-5-morpholino-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C20H24N6O
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1
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| 1 |
EC50 = 10000 nM
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CP0411226
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7-neopentyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C19H30N6
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1
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| 1 |
EC50 = 10000 nM
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CP0411227
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7-(benzo[d][1,3]dioxol-5-ylmethyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C22H26N6O2
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1
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| 1 |
EC50 = 10000 nM
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CP0417666
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5-(azepan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C22H28N6
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1
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| 1 |
EC50 = 10000 nM
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CP0417669
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7-benzyl-5-(piperazin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C20H25N7
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1
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| 1 |
EC50 = 10000 nM
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CP0428233
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5-(azocan-1-yl)-7-benzyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C23H30N6
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1
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| 1 |
EC50 = 10000 nM
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CP0435127
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1-(1-amino-7-benzyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-3-yl)ethanone
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C23H28N6O
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1
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| 1 |
EC50 = 10000 nM
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CP0435128
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7-benzyl-N-ethyl-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-amine
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C23H30N6
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1
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| 1 |
EC50 = 10000 nM
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CP0504251
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7-(4-Fluorobenzoyl)-5-(piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine
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C21H23FN6O
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1
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| 1 |
EC50 > 10000 nM
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CP0504256
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7-benzyl-N5,N5-dimethyl-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridine-1,5-diamine
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C18H22N6
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1
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| 1 |
EC50 = 10000 nM
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CP0915983
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5-(Piperidin-1-yl)-6,7,8,9-tetrahydro-3H-pyrazolo[3,4-c][2,7]naphthyridin-1-ylamine di hydrochloride
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C14H21ClN6
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1
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| 1 |
EC50 > 10000 nM
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