Brief Information of the Compound and Protein
Compound Name
2-[4-(2,2-dimethylpropyl)-1H-imidazol-2-yl]-1-[4-(5-fluoropyridin-2-yl)phenyl]propan-2-ol
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PubChem ID
CID: 25055504
SID: 56391783
Canonical SMILES
CC(C)(C)Cc1cnc([nH]1)C(C)(O)Cc1ccc(cc1)-c1ccc(F)cn1
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Compound Formula C22H26FN3O
Compound Structure
Protein Name
Bombesin receptor subtype-3
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GRP-related receptor
Uniprot ID
P32247
Gene Name
BRS3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000866 HEK293 AequoScreen Homo sapiens (Human)  1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 82 nM