| Compound ID |
Compound Name |
Compound Formula |
|
CP0563729
|
7-fluoro-4-(5-methyl-1H-imidazo[4,5-b]pyridin-6-yl)-1H-pyrazolo[4,3-b]indole
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|
C16H11FN6
|
1
|
| 1 |
EC50 = 12.59 nM
|
|
|
|
CP0032544
|
(3R)-1-[4-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyrimidin-2-yl]pyrrolidin-3-ol
Show/Hide
|
C17H16F3N5O
|
1
|
| 1 |
EC50 = 15 nM
|
|
|
|
CP0509071
|
4-(7-fluoro-1H-pyrazolo[4,3-b]indol-4-yl)-N-(2-hydroxyethyl)-3-methylbenzamide
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|
C19H17FN4O2
|
1
|
| 1 |
EC50 = 19.95 nM
|
|
|
|
CP0548710
|
4-(3,5-dimethylimidazo[4,5-b]pyridin-6-yl)-7-fluoro-1H-pyrazolo[4,3-b]indole
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|
C17H13FN6
|
1
|
| 1 |
EC50 = 25.12 nM
|
|
|
|
CP0399419
|
3-chloro-5-(7-fluoro-1H-pyrazolo[4,3-b]indol-4-yl)pyridin-2-amine
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|
C14H9ClFN5
|
1
|
| 1 |
EC50 = 31.62 nM
|
|
|
|
CP0452646
|
N-(2-hydroxyethyl)-3-methoxy-4-[6-(trifluoromethyl)-1H-indazol-4-yl]benzamide
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|
C18H16F3N3O3
|
1
|
| 1 |
EC50 = 37 nM
|
|
|
|
CP0554806
|
(3R)-1-[6-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyridin-2-yl]pyrrolidin-3-ol
Show/Hide
|
C18H17F3N4O
|
1
|
| 1 |
EC50 = 38 nM
|
|
|
|
CP0509007
|
N-(2-hydroxyethyl)-3-methyl-4-[6-(trifluoromethyl)-1H-indazol-4-yl]benzamide
Show/Hide
|
C18H16F3N3O2
|
1
|
| 1 |
EC50 = 60 nM
|
|
|
|
CP0409981
|
(3S)-1-[6-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyridin-2-yl]pyrrolidin-3-ol
Show/Hide
|
C18H17F3N4O
|
1
|
| 1 |
EC50 = 65 nM
|
|
|
|
CP0534641
|
7-fluoro-4-pyridin-3-yl-1H-pyrazolo[4,3-b]indole
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|
C14H9FN4
|
1
|
| 1 |
EC50 = 100 nM
|
|
|
|
CP0443513
|
(3S)-1-[4-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyrimidin-2-yl]pyrrolidin-3-ol
Show/Hide
|
C17H16F3N5O
|
1
|
| 1 |
EC50 = 121 nM
|
|
|
|
CP0376311
|
3-fluoro-N-(2-hydroxyethyl)-4-[6-(trifluoromethyl)-1H-indazol-4-yl]benzamide
Show/Hide
|
C17H13F4N3O2
|
1
|
| 1 |
EC50 = 234 nM
|
|
|
|
CP0407908
|
7-fluoro-4-(7-methyl-1H-imidazo[4,5-b]pyridin-6-yl)-1H-pyrazolo[4,3-b]indole
Show/Hide
|
C16H11FN6
|
1
|
| 1 |
EC50 = 251.19 nM
|
|
|
|
CP0554805
|
N-(2-hydroxyethyl)-4-methyl-5-[6-(trifluoromethyl)-1H-indazol-4-yl]pyridine-2-carboxamide
Show/Hide
|
C17H15F3N4O2
|
1
|
| 1 |
EC50 = 770 nM
|
|
|
|
CP0376301
|
6,7-difluoro-4-pyridin-3-yl-1H-pyrazolo[4,3-b]indole
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|
C14H8F2N4
|
1
|
| 1 |
EC50 = 1258.93 nM
|
|
|
|
CP0563728
|
4-(7-fluoro-1H-pyrazolo[4,3-b]indol-4-yl)-N-(2-hydroxyethyl)benzamide
Show/Hide
|
C18H15FN4O2
|
1
|
| 1 |
EC50 = 1995.26 nM
|
|
|
|
CP0509073
|
6-chloro-4-pyridin-3-yl-1H-pyrazolo[4,3-b]indole
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|
C14H9ClN4
|
1
|
| 1 |
EC50 = 10000 nM
|
|
|
|
CP0477267
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-1-(3-chloro-1H-pyrrolo[2,3-b]pyridin-5-yl)-3-hydroxy-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C19H15Cl2FN4O3
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0371533
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-1-(1H-indol-5-yl)-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C20H17ClFN3O3
|
1
|
| 1 |
IC50 = 12 nM
|
|
|
|
CP0355581
|
US10005756, Compound A79
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|
C19H15ClF2N4O3
|
1
|
| 1 |
IC50 = 13 nM
|
|
|
|
CP0232986
|
5-[(3S)-3-[(3-chloro-5-fluorophenyl)methylcarbamoyl]-3-hydroxy-2-oxopyrrolidin-1-yl]-N-ethyl-1H-indole-2-carboxamide
Show/Hide
|
C23H22ClFN4O4
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0350678
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-1-(2-methyl-1H-indol-5-yl)-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C21H19ClFN3O3
|
1
|
| 1 |
IC50 = 14 nM
|
|
|
|
CP0164309
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H19ClFN3O4
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0368892
|
(3S)-N-[(3-chloro-2,5-difluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H18ClF2N3O4
|
1
|
| 1 |
IC50 = 16 nM
|
|
|
|
CP0371532
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-2-oxo-1-(1H-pyrrolo[2,3-b]pyridin-5-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C19H16ClFN4O3
|
1
|
| 1 |
IC50 = 18 nM
|
|
|
|
CP0355582
|
(3S)-N-[(3,5-difluorophenyl)methyl]-3-hydroxy-1-(1H-indol-5-yl)-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C20H17F2N3O3
|
1
|
| 1 |
IC50 = 20 nM
|
|
|
|
CP0143027
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-1-(1H-indazol-5-yl)-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C19H16ClFN4O3
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0232985
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-1-[3-(methanesulfonamido)phenyl]-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C19H19ClFN3O5S
|
1
|
| 1 |
IC50 = 46 nM
|
|
|
|
CP0556579
|
(3S)-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)-N-[(2,3,5-trifluorophenyl)methyl]pyrrolidine-3-carboxamide
Show/Hide
|
C21H18F3N3O4
|
1
|
| 1 |
IC50 = 49 nM
|
|
|
|
CP0757713
|
(S)-3-Hydroxy-2-oxo-1-(1H-pyrrolo[2,3-b]pyridin-5-yl)-pyrrolidine-3-carboxylic Acid 3,5-Difluoro-benzylamide
Show/Hide
|
C19H16F2N4O3
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0239916
|
(3S)-N-[(3-chloro-2-fluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H19ClFN3O4
|
1
|
| 1 |
IC50 = 68 nM
|
|
|
|
CP0239917
|
US10005756, Compound A75
Show/Hide
|
C19H16F2N4O3
|
1
|
| 1 |
IC50 = 72 nM
|
|
|
|
CP0556757
|
(3S)-N-[(3,5-difluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H19F2N3O4
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0350677
|
(3S)-N-[(2,3-difluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H19F2N3O4
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0368739
|
(3S)-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)-N-[(2,3,6-trifluorophenyl)methyl]pyrrolidine-3-carboxamide
Show/Hide
|
C21H18F3N3O4
|
1
|
| 1 |
IC50 = 170 nM
|
|
|
|
CP0757715
|
5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide
Show/Hide
|
C24H25ClFN5O4
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0244234
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-1-(1-methyl-2-oxo-3,4-dihydroquinolin-6-yl)-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C22H21ClFN3O4
|
1
|
| 1 |
IC50 = 490 nM
|
|
|
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CP0098551
|
(3S)-N-[(2,6-difluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H19F2N3O4
|
1
|
| 1 |
IC50 = 809 nM
|
|
|
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CP0344007
|
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-1-(8-fluoro-2-oxo-3,4-dihydro-1H-quinolin-6-yl)-3-hydroxy-2-oxopyrrolidine-3-carboxamide
Show/Hide
|
C21H18ClF2N3O4
|
1
|
| 1 |
IC50 = 900 nM
|
|
|
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CP0556580
|
(3S)-N-[(3-chloro-2,4-difluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H18ClF2N3O4
|
1
|
| 1 |
IC50 = 930 nM
|
|
|
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CP0098552
|
(3S)-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)-N-[(3,4,5-trifluorophenyl)methyl]pyrrolidine-3-carboxamide
Show/Hide
|
C21H18F3N3O4
|
1
|
| 1 |
IC50 = 1100 nM
|
|
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CP0556578
|
(3S)-N-[(2-chloro-6-fluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H19ClFN3O4
|
1
|
| 1 |
IC50 = 2757 nM
|
|
|
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CP0098549
|
(3S)-N-[(2-chloro-5-fluorophenyl)methyl]-3-hydroxy-2-oxo-1-(2-oxo-3,4-dihydro-1H-quinolin-6-yl)pyrrolidine-3-carboxamide
Show/Hide
|
C21H19ClFN3O4
|
1
|
| 1 |
IC50 = 4300 nM
|
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|
