Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-1-(1-methyl-2-oxo-3,4-dihydroquinolin-6-yl)-2-oxopyrrolidine-3-carboxamide
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 PubChem ID
CID: 89893636
Canonical SMILES
CN1C(=O)CCc2cc(ccc12)N1CC[C@](O)(C(=O)NCc2cc(F)cc(Cl)c2)C1=O
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Compound Formula C22H21ClFN3O4
Compound Structure
Protein Name
 Protein Info 
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 490 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 79 nM