Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(S)-3-(3-Chloro-5-fluoro-benzylcarbamoyl)-3-hydroxy-2-oxopyrrolidin-1-yl]-1H-indole-2-carboxylic Acid (3-Amino-propyl)-amide
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 PubChem ID
CID: 130307835
Canonical SMILES
NCCCNC(=O)c1cc2cc(N3CC[C@](O)(C(=O)NCc4cc(F)cc(Cl)c4)C3=O)ccc2[nH]1
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Compound Formula C24H25ClFN5O4
Compound Structure
Protein Name
 Protein Info 
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34 nM