Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(3S)-N-[(3-chloro-5-fluorophenyl)methyl]-3-hydroxy-1-(1H-indol-5-yl)-2-oxopyrrolidine-3-carboxamide
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 PubChem ID
CID: 89893744
Canonical SMILES
O[C@@]1(CCN(C1=O)c1ccc2[nH]ccc2c1)C(=O)NCc1cc(F)cc(Cl)c1
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Compound Formula C20H17ClFN3O3
Compound Structure
Protein Name
 Protein Info 
Methionine aminopeptidase 2
Protein Classification
Enzyme
>
Protease
>
Metallo protease
>
Metallo protease MG clan
>
Metallo protease M24A subfamily
Uniprot ID
P50579
Gene Name
METAP2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 59 nM