| Compound ID |
Compound Name |
Compound Formula |
|
CP0130719
|
CHEMBL4866794
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|
C21H25N5O3S2
|
1
|
| 1 |
IC50 = 7 nM
|
|
|
|
CP0561596
|
3-[5-amino-6-(2,5-dimethyltriazol-4-yl)pyrazin-2-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C19H25N7O3S
|
1
|
| 1 |
IC50 = 9 nM
|
|
|
|
CP0322779
|
3-[5-amino-6-(cyclopropanecarbonyl)pyrazin-2-yl]-N-(4-hydroxycyclohexyl)-4-methylbenzenesulfonamide
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|
C21H26N4O4S
|
1
|
| 1 |
IC50 = 15 nM
|
|
|
|
CP0177055
|
3-[5-amino-6-(2-methyl-1,3-thiazol-5-yl)pyrazin-2-yl]-N-(3-hydroxypropyl)-4-methylbenzenesulfonamide
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|
C18H21N5O3S2
|
1
|
| 1 |
IC50 = 24 nM
|
|
|
|
CP0562074
|
3-[5-amino-6-(2-methyl-1,3-thiazol-5-yl)pyrazin-2-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C19H23N5O3S2
|
1
|
| 1 |
IC50 = 28 nM
|
|
|
|
CP0563436
|
3-[5-amino-6-(2-methyl-1,3-thiazol-5-yl)pyrazin-2-yl]-N-(3-hydroxy-3-methylbutyl)-4-methylbenzenesulfonamide
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|
C20H25N5O3S2
|
1
|
| 1 |
IC50 = 55 nM
|
|
|
|
CP0565057
|
3-[5-amino-6-(1,3-dimethylpyrazol-4-yl)pyrazin-2-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C20H26N6O3S
|
1
|
| 1 |
IC50 = 61 nM
|
|
|
|
CP0573660
|
3-[5-amino-6-(2-methyl-1,3-thiazol-5-yl)pyrazin-2-yl]-N-(4,4-difluorocyclohexyl)-4-methylbenzenesulfonamide
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|
C21H23F2N5O2S2
|
1
|
| 1 |
IC50 = 64 nM
|
|
|
|
CP0576364
|
3-(6-Amino-5-(3-methylisoxazol-5-yl)pyridin-3-yl)-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C20H24N4O4S
|
1
|
| 1 |
IC50 = 110 nM
|
|
|
|
CP0322780
|
3-(6-Amino-5-(2-methyloxazol-5-yl)pyridin-3-yl)-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C20H24N4O4S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0531421
|
3-[5-amino-6-(2-methyltriazol-4-yl)pyrazin-2-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C18H23N7O3S
|
1
|
| 1 |
IC50 = 140 nM
|
|
|
|
CP0576181
|
3-[5-amino-6-(3-methyl-1,2-oxazol-5-yl)pyrazin-2-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C19H23N5O4S
|
1
|
| 1 |
IC50 = 150 nM
|
|
|
|
CP0576363
|
3-(6-amino-5-(2-methyl-2H-1,2,3-triazol-4-yl)pyridin-3-yl)-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide hydrochloride
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|
C19H24N6O3S
|
1
|
| 1 |
IC50 = 151 nM
|
|
|
|
CP0555796
|
3-(6-Amino-5-(3-methyl-1,2,4-oxadiazol-5-yl)pyridin-3-yl)-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide, hydrochloride salt
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|
C19H23N5O4S
|
1
|
| 1 |
IC50 = 200 nM
|
|
|
|
CP0570128
|
3-[5-amino-6-(3-methylpyrazol-1-yl)pyrazin-2-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C19H24N6O3S
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0570699
|
3-[6-Amino-5-(2-methyl-thiazol-5-yl)-pyridin-3-yl]-N-(2-hydroxy-2-methyl-propyl)-4-methyl-benzenesulfonamide
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|
C20H24N4O3S2
|
1
|
| 1 |
IC50 = 240 nM
|
|
|
|
CP0547781
|
3-[5-amino-6-(1,2,4-triazol-1-yl)pyrazin-2-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C17H21N7O3S
|
1
|
| 1 |
IC50 = 350 nM
|
|
|
|
CP0322778
|
3-amino-6-[4-chloro-3-[(3,4-difluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
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|
C18H14ClF2N5O3S
|
1
|
| 1 |
IC50 = 352 nM
|
|
|
|
CP0355773
|
3-[6-amino-5-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C20H25N5O3S
|
1
|
| 1 |
IC50 = 400 nM
|
|
|
|
CP0576530
|
3-[6-amino-5-(5-methyl-1,3,4-oxadiazol-2-yl)pyridin-3-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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|
C19H23N5O4S
|
1
|
| 1 |
IC50 = 470 nM
|
|
|
|
CP0130728
|
1-[2-(2-ethyltetrazol-5-yl)ethyl]-3-[5-(3-fluoro-4-methylsulfonylphenyl)-4-methyl-1,3-thiazol-2-yl]urea
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|
C17H20FN7O3S2
|
1
|
| 1 |
IC50 = 810 nM
|
|
|
