Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-amino-6-[4-chloro-3-[(3,4-difluorophenyl)sulfamoyl]phenyl]-N-methylpyrazine-2-carboxamide
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Canonical SMILES
CNC(=O)c1nc(cnc1N)-c1ccc(Cl)c(c1)S(=O)(=O)Nc1ccc(F)c(F)c1
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Compound Formula C18H14ClF2N5O3S
Compound Structure
Protein Name
 Protein Info 
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 352 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM