Brief Information of the Compound and Protein
Compound Name
3-[6-amino-5-(1-methylpyrazol-4-yl)pyridin-3-yl]-N-(2-hydroxy-2-methylpropyl)-4-methylbenzenesulfonamide
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Canonical SMILES
Cc1ccc(cc1-c1cnc(N)c(c1)-c1cnn(C)c1)S(=O)(=O)NCC(C)(C)O
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Compound Formula C20H25N5O3S
Compound Structure
Protein Name
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P48736
Gene Name
PIK3CG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 88 nM