Brief Information of the Cell Line and Protein
Cell Line ID: CL000068 , A-549
 Cell Line Info 
Synonyms
A 549
A549
NCI-A549
A549/ATCC
A549 ATCC
A549ATCC
hA549
Category Cancer cell line
Organism
Homo sapiens (Human)
Cellosaurus ID
CVCL_0023
Protein ID: PT02021 , Transitional endoplasmic reticulum ATPase
 Protein Info 
Gene Name VCP
Organism Homo sapiens, Human
Protein Classification Transporter
Uniprot ID P55072
Table of Molecular Bioactivities Related to the Cell Line and Protein
Cell Line ID: CL000068
 Cell Line Info 
 Protein ID: PT02021
 Protein Info 
 
Compound ID Compound Name Compound Formula
CP0234347
 Compound Info 
1-[4-(benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl]-2-methylindole-4-carboxamide
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C25H25N5O
  3
1
IC50 = 250 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 500 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 580 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0064199
 Compound Info 
Cb 5083
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C24H23N5O2
  3
1
IC50 = 490 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 680 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 1030 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0420601
 Compound Info 
1-[4-(benzylamino)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl]-2-methylindole-4-carboxamide
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C24H24N6O
  3
1
IC50 = 1790 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 2000 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 2860 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0149103
 Compound Info 
N-benzyl-2-(2-methoxybenzimidazol-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amine
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C23H23N5O
  3
1
IC50 = 4240 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 4840 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
3
IC50 = 9340 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0321487
 Compound Info 
2-(2-aminobenzimidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine
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C23H20N6O
  2
1
IC50 = 6140 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 6610 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
CP0099592
 Compound Info 
US9062026, Table III, Compound 43
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C23H23N5
  2
1
IC50 = 9150 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS
2
IC50 = 15320 nM
 Bioactivity Info 
   TI
   LI
   LO
   TS