Brief Information of the Compound and Protein
Compound Name
N-benzyl-2-(2-methoxybenzimidazol-1-yl)-5,6,7,8-tetrahydroquinazolin-4-amine
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PubChem ID
CID: 73052241
Canonical SMILES
COc1nc2ccccc2n1-c1nc2CCCCc2c(NCc2ccccc2)n1
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Compound Formula C23H23N5O
Compound Structure
Protein Name
Transitional endoplasmic reticulum ATPase
Protein Classification
Transporter
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Primary active transporter
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Endoplasmic reticular retrotranslocon family
Uniprot ID
P55072
Gene Name
VCP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  3
1
IC50 = 4240 nM
   TI
   LI
   LO
   TS
2
IC50 = 4840 nM
   TI
   LI
   LO
   TS
3
IC50 = 9340 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 76 nM