Brief Information of the Compound and Protein
Compound Name
2-(2-aminobenzimidazol-1-yl)-N-benzyl-8-methoxyquinazolin-4-amine
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PubChem ID
CID: 49830258
SID: 163519957
Canonical SMILES
COc1cccc2c(NCc3ccccc3)nc(nc12)-n1c(N)nc2ccccc12
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Compound Formula C23H20N6O
Compound Structure
Protein Name
Transitional endoplasmic reticulum ATPase
Protein Classification
Transporter
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Primary active transporter
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Endoplasmic reticular retrotranslocon family
Uniprot ID
P55072
Gene Name
VCP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
IC50 = 6140 nM
   TI
   LI
   LO
   TS
2
IC50 = 6610 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 110 nM
2 IC50 = 815 nM