Brief Information of the Compound and Protein
Compound Name
US9062026, Table III, Compound 43
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PubChem ID
CID: 73052718
Canonical SMILES
Cc1cc2ccccc2n1-c1nc2CCNCc2c(NCc2ccccc2)n1
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Compound Formula C23H23N5
Compound Structure
Protein Name
Transitional endoplasmic reticulum ATPase
Protein Classification
Transporter
>
Primary active transporter
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Endoplasmic reticular retrotranslocon family
Uniprot ID
P55072
Gene Name
VCP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
IC50 = 9150 nM
   TI
   LI
   LO
   TS
2
IC50 = 15320 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 192 nM
2 IC50 < 2000 nM