Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[4-(benzylamino)-5,6,7,8-tetrahydroquinazolin-2-yl]-2-methylindole-4-carboxamide
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 PubChem ID
CID: 73052878
Canonical SMILES
Cc1cc2c(cccc2n1-c1nc2CCCCc2c(NCc2ccccc2)n1)C(N)=O
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Compound Formula C25H25N5O
Compound Structure
Protein Name
 Protein Info 
Transitional endoplasmic reticulum ATPase
Protein Classification
Transporter
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Primary active transporter
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Endoplasmic reticular retrotranslocon family
Uniprot ID
P55072
Gene Name
VCP
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  3
1
IC50 = 250 nM
   TI
   LI
   LO
   TS
2
IC50 = 500 nM
   TI
   LI
   LO
   TS
3
IC50 = 580 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 6 nM
2 Ki = 28.6 nM