AZD-9291

(R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)prop-2-en-1-one

(R)-1-(3-(4-Amino-3-(3-chloro-4-(pyridin-2-ylmethoxy)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one

3-[4-(3-bromoanilino)-6-methoxyquinazolin-7-yl]oxypropyl 3-(prop-2-enyldisulfanyl)propanoate

2-But-3-enyldisulfanyl-N-[4-(3-trifluoromethyl-phenylamino)-quinazolin-6-yl]-acetamide

2-But-3-enyldisulfanyl-N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]-acetamide

N-[4-(3-Chloro-4-fluoro-phenylamino)-quinazolin-6-yl]-2-[4-(3-oxo-3H-[1,2]dithiol-4-yl)-phenoxy]-acetamide

4-(4-{3-[4-(3-Bromo-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

2-[4-(3-Oxo-3H-[1,2]dithiol-4-yl)-phenoxy]-N-[4-(3-trifluoromethyl-phenylamino)-quinazolin-6-yl]-acetamie

4-(4-{3-[6-Methoxy-4-(4-nitro-phenylamino)-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

4-(4-{3-[4-(4-Bromo-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

4-(4-{3-[4-(3,4-Dimethoxy-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-but-3-enyldisulfanyl-acetamide

N-[4-(3-Bromo-phenylamino)-quinazolin-6-yl]-2-[4-(3-oxo-3H-[1,2]dithiol-4-yl)-phenoxy]-acetamide

4-(4-{3-[6-Methoxy-4-(3-trifluoromethyl-phenylamino)-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

4-(4-{3-[4-(3-Chloro-4-fluoro-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propoxy}-phenyl)-[1,2]dithiole-3-thione

3-Allyldisulfanyl-propionic acid 3-[4-(4-bromo-phenylamino)-6-methoxy-quinazolin-7-yloxy]-propyl ester

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-pyridin-3-ylsulfanylacetate

N-[3-[[2-[4-(4-methylpiperazin-1-yl)anilino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

N-[3-[[2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

4-N-(3-bromophenyl)-6-N-(3-piperidin-1-ylpropyl)quinazoline-4,6-diamine

4-anilinoquinazoline deriv. 2

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-(1-methyltetrazol-5-yl)sulfanylacetate

N-[4-(3-bromoanilino)quinazolin-6-yl]-4-piperidin-1-ylbutanamide

N-[4-(3-chloro-4-fluoroanilino)-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]prop-2-enamide

N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]prop-2-enamide

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-chloroacetate

N-[3-[[2-[(1-methylpyrazol-3-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxy]phenyl]prop-2-enamide

N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(dimethylamino)propanamide

N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-(1-methylimidazol-2-yl)sulfanylacetate

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-(1-methylbenzimidazol-2-yl)sulfanylacetate

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 3-pyridin-3-ylpropanoate

N-[4-(3-chloro-4-fluoroanilino)-7-prop-2-ynoxyquinazolin-6-yl]prop-2-enamide

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] prop-2-enoate

4-Anilinoquinazoline deriv. 45

N-[4-(3-bromoanilino)quinazolin-6-yl]-3-phenoxypropanamide

[2-[[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl]amino]-2-oxoethyl] benzoate

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-(1H-imidazol-2-ylsulfanyl)acetate

N-[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl]-2-hydroxyacetamide

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-pyrimidin-2-ylsulfanylacetate

[2-[[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl]amino]-2-oxoethyl] acetate

N-(3-chloro-4-fluorophenyl)-7-methoxy-6-(3-morpholin-4-ylpropoxy)quinazolin-4-amine

[2-[[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl]amino]-2-oxoethyl] 2,6-dimethylbenzoate

N-[4-(3-bromoanilino)quinazolin-6-yl]-2-(2,3,4,5,6-pentafluorophenoxy)acetamide

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-pyridin-2-ylsulfanylacetate

N-[(3R,4R)-1-[9-ethyl-6-[(3-methoxy-1-methylpyrazol-4-yl)amino]purin-2-yl]-4-fluoropyrrolidin-3-yl]prop-2-enamide

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-(1,3-benzothiazol-2-ylsulfanyl)acetate

N-[(3R,4R)-4-fluoro-1-[6-[[3-methoxy-1-(1-methylpyrrolidin-3-yl)pyrazol-4-yl]amino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

N-[2-[2-(dimethylamino)ethyl-methylamino]-4-methoxy-5-[[2-(1-methylindol-3-yl)pyrimidin-4-yl]amino]phenyl]prop-2-enamide

N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

N-[(3R,4R)-4-fluoro-1-[6-[(1-methylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

1-[(3aS,6aR)-2-[6-[4-(4-methylpiperazin-1-yl)anilino]-9-propan-2-ylpurin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]prop-2-en-1-one

N-[(3R,4R)-1-[6-[(1-ethyl-3-methoxypyrazol-4-yl)amino]-9-methylpurin-2-yl]-4-fluoropyrrolidin-3-yl]prop-2-enamide

[4-(3-chloro-4-fluoroanilino)-7-ethoxyquinazolin-6-yl] 2-[(5-methoxy-1,3-benzothiazol-2-yl)sulfanyl]acetate

N-[(3S)-1-[6-[4-(4-methylpiperazin-1-yl)anilino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

Mavelertinib

1-[(3R)-3-[[6-[4-(4-methylpiperazin-1-yl)anilino]-9-propan-2-ylpurin-2-yl]amino]pyrrolidin-1-yl]prop-2-en-1-one

N-[(3R,4R)-1-[6-[(3-ethyl-1-methylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]-4-fluoropyrrolidin-3-yl]prop-2-enamide

N-[(3S)-1-[6-[(1-methylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

N-[(3R,4R)-1-[9-tert-butyl-6-[(3-methoxy-1-methylpyrazol-4-yl)amino]purin-2-yl]-4-fluoropyrrolidin-3-yl]prop-2-enamide

N-[(3R,4R)-4-fluoro-1-[6-[(3-methoxy-1-methylpyrazol-4-yl)amino]-7H-purin-2-yl]pyrrolidin-3-yl]prop-2-enamide

1-[(3aS,6aR)-2-[6-[(1-methylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]-1,3,3a,4,6,6a-hexahydropyrrolo[3,4-c]pyrrol-5-yl]prop-2-en-1-one

N-[(3R,4R)-1-[6-[(1,3-dimethylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]-4-fluoropyrrolidin-3-yl]prop-2-enamide

AVL-301

1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-(trifluoromethyl)pyrrolidin-1-yl]prop-2-en-1-one

N-[(3S)-1-[9-(2-hydroxyethyl)-6-[4-(4-methylpiperazin-1-yl)anilino]purin-2-yl]pyrrolidin-3-yl]prop-2-enamide

1-[(3R,4R)-3-[[2-[(1-but-3-ynylpyrazol-4-yl)amino]-5-chloro-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-methoxypyrrolidin-1-yl]prop-2-en-1-one

1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-fluoropyrrolidin-1-yl]prop-2-en-1-one

1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-methoxypyrrolidin-1-yl]prop-2-en-1-one

1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-(methoxymethyl)pyrrolidin-1-yl]prop-2-en-1-one

1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-hydroxypyrrolidin-1-yl]prop-2-en-1-one

1-[(3R,4R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-(hydroxymethyl)pyrrolidin-1-yl]prop-2-en-1-one

1-[(3S,4S)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-methoxypyrrolidin-1-yl]prop-2-en-1-one

N-[(3S,4S)-4-fluoro-1-[6-[(1-methylpyrazol-4-yl)amino]-9-propan-2-ylpurin-2-yl]pyrrolidin-3-yl]prop-2-enamide

1-[(3S)-3-[[6-[4-(4-methylpiperazin-1-yl)anilino]-9-propan-2-ylpurin-2-yl]amino]pyrrolidin-1-yl]prop-2-en-1-one

1-[(3R)-3-[[5-chloro-2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]pyrrolidin-1-yl]prop-2-en-1-one

1-[(3R,4R)-3-[[2-[(1-methylpyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl]oxymethyl]-4-(trifluoromethyl)pyrrolidin-1-yl]prop-2-en-1-one