Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(3-bromoanilino)quinazolin-6-yl]-4-piperidin-1-ylbutanamide
    Show/Hide
 PubChem ID
CID: 72189794
Canonical SMILES
Brc1cccc(Nc2ncnc3ccc(NC(=O)CCCN4CCCCC4)cc23)c1
    Show/Hide
Compound Formula C23H26BrN5O
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 5.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 13.5 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.63 nM