Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[4-(3-bromoanilino)quinazolin-6-yl]-3-(dimethylamino)propanamide
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 PubChem ID
CID: 46239453
SID: 96101310
Canonical SMILES
CN(C)CCC(=O)Nc1ccc2ncnc(Nc3cccc(Br)c3)c2c1
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Compound Formula C19H20BrN5O
Compound Structure
Protein Name
 Protein Info 
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 8.59 nM
   TI
   LI
   LO
   TS
2
IC50 = 38.2 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.28 nM