Brief Information of the Compound and Protein
Compound Name
4-N-(3-bromophenyl)-6-N-(3-piperidin-1-ylpropyl)quinazoline-4,6-diamine
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PubChem ID
CID: 72190112
Canonical SMILES
Brc1cccc(Nc2ncnc3ccc(NCCCN4CCCCC4)cc23)c1
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Compound Formula C22H26BrN5
Compound Structure
Protein Name
Epidermal growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase EGFR family
Uniprot ID
P00533
Gene Name
EGFR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000068 A-549 Homo sapiens (Human)  2
1
IC50 = 1.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 14.1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.41 nM