| Compound ID |
Compound Name |
Compound Formula |
|
CP0299619
|
N-[5-(5-fluoro-6-methylpyridin-2-yl)-4-quinoxalin-6-yl-1H-imidazol-2-yl]-2-methoxyacetamide
Show/Hide
|
C20H17FN6O2
|
1
|
| 1 |
EC50 = 61 nM
|
|
|
|
CP0129638
|
4-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)thiazol-2-amine
Show/Hide
|
C17H13N5S
|
1
|
| 1 |
EC50 = 80 nM
|
|
|
|
CP0235343
|
N-[5-(5-fluoro-6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]acetamide
Show/Hide
|
C17H14FN7O
|
1
|
| 1 |
EC50 = 111 nM
|
|
|
|
CP0037392
|
N-[5-(5-fluoro-6-methylpyridin-2-yl)-4-quinoxalin-6-yl-1H-imidazol-2-yl]-3-methoxypropanamide
Show/Hide
|
C21H19FN6O2
|
1
|
| 1 |
EC50 = 148 nM
|
|
|
|
CP0174798
|
N-[5-(5-fluoro-6-methylpyridin-2-yl)-4-quinoxalin-6-yl-1H-imidazol-2-yl]propanamide
Show/Hide
|
C20H17FN6O
|
1
|
| 1 |
EC50 = 156 nM
|
|
|
|
CP0253998
|
N-[5-(6-methylpyridin-2-yl)-4-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-1H-imidazol-2-yl]acetamide
Show/Hide
|
C17H15N7O
|
1
|
| 1 |
EC50 = 165 nM
|
|
|
|
CP0094578
|
N-[5-(5-fluoro-6-methylpyridin-2-yl)-4-quinoxalin-6-yl-1H-imidazol-2-yl]acetamide
Show/Hide
|
C19H15FN6O
|
1
|
| 1 |
EC50 = 180 nM
|
|
|
|
CP0253996
|
6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-methylpiperazin-1-yl)-1H-imidazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridine
Show/Hide
|
C20H21FN8
|
1
|
| 1 |
EC50 = 344 nM
|
|
|
|
CP0253997
|
6-(4-(5-fluoro-6-methylpyridin-2-yl)-2-(4-(methylsulfonyl)piperazin-1-yl)-1H-imidazol-5-yl)-[1,2,4]triazolo[1,5-a]pyridine
Show/Hide
|
C20H21FN8O2S
|
1
|
| 1 |
EC50 = 414 nM
|
|
|
|
CP0235345
|
4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-fluoro-6-methylpyridin-2-yl)-1H-imidazol-2-yl)morpholine
Show/Hide
|
C19H18FN7O
|
1
|
| 1 |
EC50 = 513 nM
|
|
|
|
CP0144467
|
1-(4-(5-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(5-fluoro-6-methylpyridin-2-yl)-1H-imidazol-2-yl)piperazin-1-yl)ethanone
Show/Hide
|
C21H21FN8O
|
1
|
| 1 |
EC50 = 1220 nM
|
|
|
|
CP0007000
|
2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
Show/Hide
|
C17H13N5
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0017299
|
4-(3-Chloro-phenyl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine
Show/Hide
|
C17H11ClN4S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0276945
|
4-(6-Methyl-pyridin-2-yl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine
Show/Hide
|
C17H13N5S
|
1
|
| 1 |
IC50 = 10 nM
|
|
|
|
CP0025659
|
4-(4-Fluoro-phenyl)-5-[1,5]naphthyridin-2-yl-thiazol-2-ylamine
Show/Hide
|
C17H11FN4S
|
1
|
| 1 |
IC50 = 30 nM
|
|
|
|
CP0253995
|
4-(5-fluoro-6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)-1H-imidazol-2-amine
Show/Hide
|
C17H13FN6
|
1
|
| 1 |
IC50 = 33.5 nM
|
|
|
|
CP0276946
|
2-(3-(pyridin-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine
Show/Hide
|
C16H11N5
|
1
|
| 1 |
IC50 = 50 nM
|
|
|
|
CP0374429
|
2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-4-amine
Show/Hide
|
C20H16N4
|
1
|
| 1 |
IC50 = 58 nM
|
|
|
|
CP0167334
|
2-(6-methylpyridin-2-yl)-N-(pyrimidin-4-yl)quinazolin-4-amine
Show/Hide
|
C18H14N6
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0497533
|
2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[3,2-d]pyrimidin-4-amine
Show/Hide
|
C17H13N5S
|
1
|
| 1 |
IC50 = 60 nM
|
|
|
|
CP0262281
|
N-(1H-indazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine
Show/Hide
|
C21H16N6
|
1
|
| 1 |
IC50 = 90 nM
|
|
|
|
CP0048685
|
2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine
Show/Hide
|
C19H15N5
|
1
|
| 1 |
IC50 = 95 nM
|
|
|
|
CP0026932
|
5-(1,5-naphthyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine
Show/Hide
|
C16H11N5S
|
1
|
| 1 |
IC50 = 120 nM
|
|
|
|
CP0306957
|
5-(8-Methyl-[1,5]naphthyridin-2-yl)-4-pyridin-2-yl-thiazol-2-ylamine
Show/Hide
|
C17H13N5S
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0290283
|
4-(3-bromophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H15BrN4O
|
1
|
| 1 |
IC50 = 220 nM
|
|
|
|
CP0036041
|
4-(4-(benzo[d][1,3]dioxol-5-yl)-5-(pyridin-2-yl)-1H-imidazol-2-yl)benzamide
Show/Hide
|
C22H16N4O3
|
1
|
| 1 |
IC50 = 250 nM
|
|
|
|
CP0162103
|
5-(6-Methyl-[1,5]naphthyridin-4-yl)-4-pyridin-2-yl-thiazol-2-ylamine
Show/Hide
|
C17H13N5S
|
1
|
| 1 |
IC50 = 260 nM
|
|
|
|
CP0510544
|
5-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)thieno[2,3-d]pyrimidin-4-amine
Show/Hide
|
C18H15N5S
|
1
|
| 1 |
IC50 = 318 nM
|
|
|
|
CP0040672
|
2-(4-methylthiazol-2-yl)-N-(pyridin-4-yl)quinazolin-4-amine
Show/Hide
|
C17H13N5S
|
1
|
| 1 |
IC50 = 342 nM
|
|
|
|
CP0060328
|
4-(3-ethylphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C21H20N4O
|
1
|
| 1 |
IC50 = 390 nM
|
|
|
|
CP0179244
|
4-(pyridin-2-yl)-5-(quinolin-4-yl)thiazol-2-amine
Show/Hide
|
C17H12N4S
|
1
|
| 1 |
IC50 = 420 nM
|
|
|
|
CP0071413
|
3-(2-(6-methylpyridin-2-yl)quinazolin-4-ylamino)benzamide
Show/Hide
|
C21H17N5O
|
1
|
| 1 |
IC50 = 545 nM
|
|
|
|
CP0268900
|
1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-vinylphenyl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C21H18N4O
|
1
|
| 1 |
IC50 = 560 nM
|
|
|
|
CP0459182
|
6-methyl-2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)pyrimidin-4-amine
Show/Hide
|
C16H15N5
|
1
|
| 1 |
IC50 = 745 nM
|
|
|
|
CP0309222
|
N-(1-methylindazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine
Show/Hide
|
C22H18N6
|
1
|
| 1 |
IC50 = 794 nM
|
|
|
|
CP0309105
|
4-(3-fluorophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H15FN4O
|
1
|
| 1 |
IC50 = 990 nM
|
|
|
|
CP0308588
|
2-(6-methylpyridin-2-yl)-N-(2-methylpyridin-4-yl)quinazolin-4-amine
Show/Hide
|
C20H17N5
|
1
|
| 1 |
IC50 = 1017 nM
|
|
|
|
CP0255496
|
1,2-dimethyl-4-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H17N5O
|
1
|
| 1 |
IC50 = 1030 nM
|
|
|
|
CP0060325
|
1,2-dimethyl-5-(quinoxalin-6-yl)-4-(3-(trifluoromethyl)phenyl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C20H15F3N4O
|
1
|
| 1 |
IC50 = 1100 nM
|
|
|
|
CP0309103
|
4-(3-methoxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C20H18N4O2
|
1
|
| 1 |
IC50 = 1400 nM
|
|
|
|
CP0308587
|
2-(3-chlorophenyl)-N-(pyridin-4-yl)quinazolin-4-amine
Show/Hide
|
C19H13ClN4
|
1
|
| 1 |
IC50 = 1612 nM
|
|
|
|
CP0144243
|
1,2-dimethyl-4-(pyridin-2-yl)-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C18H15N5O
|
1
|
| 1 |
IC50 = 1700 nM
|
|
|
|
CP0345069
|
4-(3-chlorophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H15ClN4O
|
1
|
| 1 |
IC50 = 1900 nM
|
|
|
|
CP0167329
|
2-phenyl-N-(pyridin-4-yl)quinazolin-4-amine
Show/Hide
|
C19H14N4
|
1
|
| 1 |
IC50 = 2465 nM
|
|
|
|
CP0308546
|
1,2-dimethyl-5-(quinoxalin-6-yl)-4-m-tolyl-1H-pyrazol-3(2H)-one
Show/Hide
|
C20H18N4O
|
1
|
| 1 |
IC50 = 3050 nM
|
|
|
|
CP0309104
|
4-(3-(methoxymethyl)phenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C21H20N4O2
|
1
|
| 1 |
IC50 = 3690 nM
|
|
|
|
CP0095082
|
DABRAFENIB
Show/Hide
|
C23H20F3N5O2S2
|
1
|
| 1 |
IC50 = 3700 nM
|
|
|
|
CP0355251
|
2-(3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihydro-1H-pyrazol-4-yl)phenyl)acetonitrile
Show/Hide
|
C21H17N5O
|
1
|
| 1 |
IC50 = 4400 nM
|
|
|
|
CP0162102
|
5''-Quinolin-4-yl-[2,4'']bithiazolyl-2''-ylamine
Show/Hide
|
C15H10N4S2
|
1
|
| 1 |
IC50 = 6580 nM
|
|
|
|
CP0230882
|
4-(2-Fluoro-phenyl)-5-quinolin-4-yl-thiazol-2-ylamine
Show/Hide
|
C18H12FN3S
|
1
|
| 1 |
IC50 = 6670 nM
|
|
|
|
CP0137693
|
4-(5-Chloro-pyridin-2-yl)-5-quinolin-4-yl-thiazol-2-ylamine
Show/Hide
|
C17H11ClN4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0230883
|
4-(pyridin-3-yl)-5-(quinolin-4-yl)thiazol-2-amine
Show/Hide
|
C17H12N4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0254009
|
5-(naphthalen-1-yl)-4-(pyridin-2-yl)thiazol-2-amine
Show/Hide
|
C18H13N3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0256271
|
4-Pyridin-2-yl-5-quinolin-2-yl-thiazol-2-ylamine
Show/Hide
|
C17H12N4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0296559
|
4-(5-Methyl-pyridin-2-yl)-5-quinolin-4-yl-thiazol-2-ylamine
Show/Hide
|
C18H14N4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0296560
|
5-[1,8]Naphthyridin-4-yl-4-pyridin-2-yl-thiazol-2-ylamine
Show/Hide
|
C16H11N5S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0302814
|
5-(6-Ethoxy-[1,5]naphthyridin-2-yl)-4-pyridin-2-yl-thiazol-2-ylamine
Show/Hide
|
C18H15N5OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0316655
|
4-(4-Chloro-pyridin-2-yl)-5-quinolin-4-yl-thiazol-2-ylamine
Show/Hide
|
C17H11ClN4S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0509749
|
4-(2-Methoxy-phenyl)-5-quinolin-4-yl-thiazol-2-ylamine
Show/Hide
|
C19H15N3OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0151431
|
1,2-dimethyl-4-phenyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H16N4O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0192238
|
1,2-dimethyl-4-(3-(methylthio)phenyl)-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C20H18N4OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0192239
|
N-[3-(1,2-dimethyl-3-oxo-5-quinoxalin-6-ylpyrazol-4-yl)phenyl]methanesulfonamide
Show/Hide
|
C20H19N5O3S
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0194799
|
4-(3-aminophenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H17N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0226830
|
1,2-dimethyl-5-(quinoxalin-6-yl)-4-(thiophen-3-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C17H14N4OS
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0255500
|
4-(2-hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0255504
|
2-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihydro-1H-pyrazol-4-yl)benzonitrile
Show/Hide
|
C20H15N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0268898
|
4-(3-hydroxyphenyl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C19H16N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0285411
|
4-(furan-3-yl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C17H14N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0306823
|
3-(1,2-dimethyl-3-oxo-5-(quinoxalin-6-yl)-2,3-dihydro-1H-pyrazol-4-yl)benzonitrile
Show/Hide
|
C20H15N5O
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0345070
|
4-(furan-2-yl)-1,2-dimethyl-5-(quinoxalin-6-yl)-1H-pyrazol-3(2H)-one
Show/Hide
|
C17H14N4O2
|
1
|
| 1 |
IC50 > 10000 nM
|
|
|
|
CP0182028
|
N-[2-(6-methylpyridin-2-yl)quinazolin-4-yl]-1,3-benzothiazol-6-amine
Show/Hide
|
C21H15N5S
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
|
CP0278644
|
N-(2H-benzotriazol-5-yl)-2-(6-methylpyridin-2-yl)quinazolin-4-amine
Show/Hide
|
C20H15N7
|
1
|
| 1 |
IC50 > 5000 nM
|
|
|
