Brief Information of the Compound and Protein
Compound Name
4-(5-Chloro-pyridin-2-yl)-5-quinolin-4-yl-thiazol-2-ylamine
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PubChem ID
CID: 11772123
SID: 16881288
Canonical SMILES
Nc1nc(c(s1)-c1ccnc2ccccc12)-c1ccc(Cl)cn1
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Compound Formula C17H11ClN4S
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
>
TKL protein kinase STKR family
>
TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 > 10000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1770 nM