Brief Information of the Compound and Protein
Compound Name
2-(6-methylpyridin-2-yl)-N-(pyridin-4-yl)quinolin-4-amine
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PubChem ID
CID: 10086873
SID: 15073649
Canonical SMILES
Cc1cccc(n1)-c1cc(Nc2ccncc2)c2ccccc2n1
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Compound Formula C20H16N4
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
IC50 = 58 nM
   TI
   LI
   LO
   TS
CL000013 Sf9 Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 22 nM
   TI
   LI
   LO
   TS