Brief Information of the Compound and Protein
Compound Name
4-(6-methylpyridin-2-yl)-5-(quinoxalin-6-yl)thiazol-2-amine
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PubChem ID
CID: 44571365
Canonical SMILES
Cc1cccc(n1)-c1nc(N)sc1-c1ccc2nccnc2c1
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Compound Formula C17H13N5S
Compound Structure
Protein Name
TGF-beta receptor type-1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TKL protein kinase group
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TKL protein kinase STKR family
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TKL protein kinase STKR Type 1 subfamily
Uniprot ID
P36897
Gene Name
TGFBR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000063 Hep-G2 Homo sapiens (Human)  1
1
EC50 = 80 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.33 nM